Exosomal miR-409-3p secreted from activated mast cells promotes microglial migration, activation and neuroinflammation by targeting Nr4a2 to activate the NF-κB pathway

A role for glia maturation factor dependent activation of mast cells and microglia in MPTP induced dopamine loss and behavioural deficits in mice

(2020) Govindhasamy Pushpavathi Selvakumar et al.   BRAIN BEHAVIOR AND IMMUNITY

Exosomal miR‐103‐3p from LPS‐activated THP‐1 macrophage contributes to the activation of hepatic stellate cells

(2020) Lisha Chen et al.   FASEB JOURNAL

Exosome‐mediated transfer of miR‐1260b promotes cell invasion through Wnt/β–catenin signaling pathway in lung adenocarcinoma

(2020) Yang Xia et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Anti-inflammatory IL-10 administration rescues depression-associated learning and memory deficits in mice

(2020) Ryan J. Worthen et al.   Journal of Neuroinflammation

Molecular Insights into NR4A2(Nurr1): an Emerging Target for Neuroprotective Therapy Against Neuroinflammation and Neuronal Cell Death

(2019) Md. Jakaria et al.   MOLECULAR NEUROBIOLOGY

TLR4 Receptor Induces 2-AG–Dependent Tolerance to Lipopolysaccharide and Trafficking of CB2 Receptor in Mast Cells

(2019) Zyanya P. Espinosa-Riquer et al.   JOURNAL OF IMMUNOLOGY

Stabilization of Brain Mast Cells Alleviates LPS-Induced Neuroinflammation by Inhibiting Microglia Activation

(2019) Hongquan Dong et al.   Frontiers in Cellular Neuroscience

In vivo evidence for the contribution of peripheral circulating inflammatory exosomes to neuroinflammation

(2018) Jing Jing Li et al.   Journal of Neuroinflammation

MiR-409-3p and MiR-1896 co-operatively participate in IL-17-induced inflammatory cytokine production in astrocytes and pathogenesis of EAE mice via targeting SOCS3/STAT3 signaling

(2018) Xiaomei Liu et al.   GLIA

Polysaccharides from Ganoderma lucidum attenuate microglia-mediated neuroinflammation and modulate microglial phagocytosis and behavioural response

(2017) Qing Cai et al.   Journal of Neuroinflammation

Matairesinol Suppresses Neuroinflammation and Migration Associated with Src and ERK1/2-NF-κB Pathway in Activating BV2 Microglia

(2017) Peng Xu et al.   NEUROCHEMICAL RESEARCH

Mast Cell Degranulation Is Accompanied by the Release of a Selective Subset of Extracellular Vesicles That Contain Mast Cell–Specific Proteases

(2016) Tom Groot Kormelink et al.   JOURNAL OF IMMUNOLOGY

Activated brain mast cells contribute to postoperative cognitive dysfunction by evoking microglia activation and neuronal apoptosis

(2016) Xiang Zhang et al.   Journal of Neuroinflammation

The pharmacological stimulation of Nurr1 improves cognitive functions via enhancement of adult hippocampal neurogenesis

(2016) Jin-il Kim et al.   Stem Cell Research

Preoperative Serum MicroRNA-155 Expression Independently Predicts Postoperative Cognitive Dysfunction After Laparoscopic Surgery for Colon Cancer

(2016) Chaoshuang Wu et al.   MEDICAL SCIENCE MONITOR

MiR-9 promotes microglial activation by targeting MCPIP1

(2014) Honghong Yao et al.   Nature Communications

Characterization of phenotype markers and neuronotoxic potential of polarised primary microglia in vitro

(2013) Vibol Chhor et al.   BRAIN BEHAVIOR AND IMMUNITY

Aging enhances classical activation but mitigates alternative activation in the central nervous system

(2013) Daniel C. Lee et al.   NEUROBIOLOGY OF AGING

Transformation from a neuroprotective to a neurotoxic microglial phenotype in a mouse model of ALS

(2012) Bing Liao et al.   EXPERIMENTAL NEUROLOGY

Characterisation of exosomes derived from human cells by nanoparticle tracking analysis and scanning electron microscopy

(2011) Viktoriya Sokolova et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Mast Cells as Sources and Targets of Membrane Vesicles

(2011) Irit Shefler et al.   CURRENT PHARMACEUTICAL DESIGN

A Nurr1 Pathway for Neuroprotection

(2009) Steven J. Bensinger et al.   CELL