Binding Dynamics of Disordered Linker Histone H1 with a Nucleosomal Particle

Chromatosome Structure and Dynamics from Molecular Simulations

(2020) Mehmet Ali Öztürk et al.   Annual Review of Physical Chemistry

Elucidating the influence of linker histone variants on chromatosome dynamics and energetics

(2020) Dustin C Woods et al.   NUCLEIC ACIDS RESEARCH

Emergence of chromatin hierarchical loops from protein disorder and nucleosome asymmetry

(2020) Akshay Sridhar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct Structures and Dynamics of Chromatosomes with Different Human Linker Histone Isoforms

(2020) Bing-Rui Zhou et al.   MOLECULAR CELL

Nano-Surveillance: Tracking Individual Molecules in a Sea of Chromatin

(2020) Daniël P. Melters et al.   JOURNAL OF MOLECULAR BIOLOGY

Gene-Specific H1 Eviction through a Transcriptional Activator→p300→NAP1→H1 Pathway

(2019) Miho Shimada et al.   MOLECULAR CELL

The Oligomerization Landscape of Histones

(2019) Haiqing Zhao et al.   BIOPHYSICAL JOURNAL

Sensitive effect of linker histone binding mode and subtype on chromatin condensation

(2019) Ognjen Perišić et al.   NUCLEIC ACIDS RESEARCH

Multiple Binding Configurations of Fis Protein Pairs on DNA: Facilitated Dissociation versus Cooperative Dissociation

(2019) Min-Yeh Tsai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Bridging chromatin structure and function over a range of experimental spatial and temporal scales by molecular modeling

(2019) Stephanie Portillo‐Ledesma et al.   Wiley Interdisciplinary Reviews-Computational Molecular Science

Dependence of Chromatosome Structure on Linker Histone Sequence and Posttranslational Modification

(2018) Mehmet Ali Öztürk et al.   BIOPHYSICAL JOURNAL

PAGE4 and Conformational Switching: Insights from Molecular Dynamics Simulations and Implications for Prostate Cancer

(2018) Xingcheng Lin et al.   JOURNAL OF MOLECULAR BIOLOGY

Toward an Ensemble View of Chromatosome Structure: A Paradigm Shift from One to Many

(2018) Mehmet Ali Öztürk et al.   STRUCTURE

AWSEM-IDP: A Coarse-Grained Force Field for Intrinsically Disordered Proteins

(2018) Hao Wu et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Extreme disorder in an ultrahigh-affinity protein complex

(2018) Alessandro Borgia et al.   NATURE

Structure of an H1-Bound 6-Nucleosome Array Reveals an Untwisted Two-Start Chromatin Fiber Conformation

(2018) Isabel Garcia-Saez et al.   MOLECULAR CELL

Linker histones as liquid-like glue for chromatin

(2018) Eric B. Gibbs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Highly disordered histone H1−DNA model complexes and their condensates

(2018) Abigail L. Turner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dependence of the Linker Histone and Chromatin Condensation on the Nucleosome Environment

(2017) Ognjen Perišić et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Resolving the NFκB Heterodimer Binding Paradox: Strain and Frustration Guide the Binding of Dimeric Transcription Factors

(2017) Davit A. Potoyan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structure and Dynamics of a 197 bp Nucleosome in Complex with Linker Histone H1

(2017) Jan Bednar et al.   MOLECULAR CELL

Emerging roles of linker histones in regulating chromatin structure and function

(2017) Dmitry V. Fyodorov et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Nanoscale dynamics of centromere nucleosomes and the critical roles of CENP-A

(2017) Micah P Stumme-Diers et al.   NUCLEIC ACIDS RESEARCH

Interplay between histone H1 structure and function

(2016) Alicia Roque et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Molecular dynamics of histone H1

(2016) Thomas W. Flanagan et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

H1–nucleosome interactions and their functional implications

(2016) Jan Bednar et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Coarse-Grained Protein Models and Their Applications

(2016) Sebastian Kmiecik et al.   CHEMICAL REVIEWS

Coupling between Histone Conformations and DNA Geometry in Nucleosomes on a Microsecond Timescale: Atomistic Insights into Nucleosome Functions

(2016) Alexey K. Shaytan et al.   JOURNAL OF MOLECULAR BIOLOGY

A Small Number of Residues Can Determine if Linker Histones Are Bound On or Off Dyad in the Chromatosome

(2016) Bing-Rui Zhou et al.   JOURNAL OF MOLECULAR BIOLOGY

Promiscuous Histone Mis-Assembly Is Actively Prevented by Chaperones

(2016) Haiqing Zhao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Molecular Mechanism of Facilitated Dissociation of Fis Protein from DNA

(2016) Min-Yeh Tsai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Exploring the Free Energy Landscape of Nucleosomes

(2016) Bin Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Conformational selection and dynamic adaptation upon linker histone binding to the nucleosome

(2016) Mehmet Ali Öztürk et al.   NUCLEIC ACIDS RESEARCH

The linker histone H1.0 generates epigenetic and functional intratumor heterogeneity

(2016) C. M. Torres et al.   SCIENCE

As Simple As Possible, but Not Simpler: Exploring the Fidelity of Coarse-Grained Protein Models for Simulated Force Spectroscopy

(2016) Mona Habibi et al.   PLoS Computational Biology

The H1 linker histones: multifunctional proteins beyond the nucleosomal core particle

(2015) S. P. Hergeth et al.   EMBO REPORTS

The Acetylation Landscape of the H4 Histone Tail: Disentangling the Interplay between the Specific and Cumulative Effects

(2015) David Winogradoff et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural Mechanisms of Nucleosome Recognition by Linker Histones

(2015) Bing-Rui Zhou et al.   MOLECULAR CELL

Linker histone partial phosphorylation: effects on secondary structure and chromatin condensation

(2015) Rita Lopez et al.   NUCLEIC ACIDS RESEARCH

Molecular stripping in theNF-κB/IκB/DNAgenetic regulatory network

(2015) Davit A. Potoyan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nucleosome Assembly Dynamics Involve Spontaneous Fluctuations in the Handedness of Tetrasomes

(2015) Rifka Vlijm et al.   Cell Reports

Citrullination regulates pluripotency and histone H1 binding to chromatin

(2014) Maria A. Christophorou et al.   NATURE

Predictive energy landscapes for folding  -helical transmembrane proteins

(2014) B. L. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cryo-EM Study of the Chromatin Fiber Reveals a Double Helix Twisted by Tetranucleosomal Units

(2014) F. Song et al.   SCIENCE

An experimentally-informed coarse-grained 3-site-per-nucleotide model of DNA: Structure, thermodynamics, and dynamics of hybridization

(2013) Daniel M. Hinckley et al.   JOURNAL OF CHEMICAL PHYSICS

Chromatin Compaction Protects Genomic DNA from Radiation Damage

(2013) Hideaki Takata et al.   PLoS One

Frustration in the energy landscapes of multidomain protein misfolding

(2013) W. Zheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural insights into the histone H1-nucleosome complex

(2013) B.-R. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The N-terminal domain determines the affinity and specificity of H1 binding to chromatin

(2012) Christine Öberg et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

AWSEM-MD: Protein Structure Prediction Using Coarse-Grained Physical Potentials and Bioinformatically Based Local Structure Biasing

(2012) Aram Davtyan et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Functional interplay between p53 acetylation and H1.2 phosphorylation in p53-regulated transcription

(2012) K Kim et al.   ONCOGENE

Regulation of the H4 tail binding and folding landscapes via Lys-16 acetylation

(2012) D. A. Potoyan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Predictive energy landscapes for protein-protein association

(2012) W. Zheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A unified phylogeny-based nomenclature for histone variants

(2012) Paul B Talbert et al.   Epigenetics & Chromatin

Dynamics of Nucleosomes Assessed with Time-Lapse High-Speed Atomic Force Microscopy

(2011) Atsushi Miyagi et al.   BIOCHEMISTRY

Energy Landscape Analyses of Disordered Histone Tails Reveal Special Organization of Their Conformational Dynamics

(2011) Davit A. Potoyan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

All-Atom and Coarse-Grained Molecular Dynamics Simulations of a Membrane Protein Stabilizing Polymer

(2011) Jason D. Perlmutter et al.   LANGMUIR

On the structure and dynamics of the complex of the nucleosome and the linker histone

(2011) Georgi V. Pachov et al.   NUCLEIC ACIDS RESEARCH

DNA and nucleosomes direct distinct folding of a linker histone H1 C-terminal domain

(2011) He Fang et al.   NUCLEIC ACIDS RESEARCH

Single-base resolution mapping of H1-nucleosome interactions and 3D organization of the nucleosome

(2010) S. H. Syed et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chromatin Higher-order Structure and Dynamics

(2010) C. L. Woodcock et al.   Cold Spring Harbor Perspectives in Biology

Site-specifically phosphorylated forms of H1.5 and H1.2 localized at distinct regions of the nucleus are related to different processes during the cell cycle

(2009) Heribert Talasz et al.   CHROMOSOMA

Counterion Atmosphere and Hydration Patterns near a Nucleosome Core Particle

(2009) Christopher K. Materese et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The histone H1 family: specific members, specific functions?

(2008) Annalisa Izzo et al.   BIOLOGICAL CHEMISTRY

Phosphorylation of the carboxy-terminal domain of histone H1: effects on secondary structure and DNA condensation

(2008) Alicia Roque et al.   NUCLEIC ACIDS RESEARCH

Nucleosome repeat length and linker histone stoichiometry determine chromatin fiber structure

(2008) Andrew Routh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA