Microplastics in the human digestive environment: a focus on the potential and challenges facing in vitro gut model development

Toxicity of Microplastics and Nanoplastics in Mammalian Systems

(2020) Cheryl Qian Ying Yong et al.   International Journal of Environmental Research and Public Health

A novel 3D intestine barrier model to study the immune response upon exposure to microplastics

(2020) Roman Lehner et al.   ARCHIVES OF TOXICOLOGY

Increased inheritance of structure and function of bacterial communities and pathogen propagation in plastisphere along a river with increasing antibiotics pollution gradient

(2020) Nana Xue et al.   ENVIRONMENTAL POLLUTION

Microplastics from consumer plastic food containers: Are we consuming it?

(2020) Oluniyi O. Fadare et al.   CHEMOSPHERE

Micro- and nano-plastics in edible fruit and vegetables. The first diet risks assessment for the general population

(2020) Gea Oliveri Conti et al.   ENVIRONMENTAL RESEARCH

Human organoids: model systems for human biology and medicine

(2020) Jihoon Kim et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Microplastic contamination of drinking water: A systematic review

(2020) Evangelos Danopoulos et al.   PLoS One

Microplastics in Honey, Beer, Milk and Refreshments in Ecuador as Emerging Contaminants

(2020) Milene F. Diaz-Basantes et al.   Sustainability

Bacillus subtilis HU58 and Bacillus coagulans SC208 Probiotics Reduced the Effects of Antibiotic-Induced Gut Microbiome Dysbiosis in an M-SHIME® Model

(2020) Massimo Marzorati et al.   Microorganisms

Comparative methods for fecal sample storage to preserve gut microbial structure and function in an in vitro model of the human colon

(2020) Charlotte Deschamps et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Spatial and temporal modulation of enterotoxigenic E. coli H10407 pathogenesis and interplay with microbiota in human gut models

(2020) Charlène Roussel et al.   BMC BIOLOGY

Influence of the digestive process on intestinal toxicity of polystyrene microplastics as determined by in vitro Caco-2 models

(2020) Su Liu et al.   CHEMOSPHERE

Microplastics release phthalate esters and cause aggravated adverse effects in the mouse gut

(2020) Yongfeng Deng et al.   ENVIRONMENT INTERNATIONAL

Strong influence of surfactants on virgin hydrophobic microplastics adsorbing ionic organic pollutants

(2020) Yan Xia et al.   ENVIRONMENTAL POLLUTION

Microplastics Reduce Lipid Digestion in Simulated Human Gastrointestinal System

(2020) Huiwen Tan et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Estimation of the mass of microplastics ingested – A pivotal first step towards human health risk assessment

(2020) Kala Senathirajah et al.   JOURNAL OF HAZARDOUS MATERIALS

Evidence of selective enrichment of bacterial assemblages and antibiotic resistant genes by microplastics in urban rivers

(2020) Jie Wang et al.   WATER RESEARCH

Adsorption behavior of the antibiotic levofloxacin on microplastics in the presence of different heavy metals in an aqueous solution

(2020) Fei Yu et al.   CHEMOSPHERE

Are We Speaking the Same Language? Recommendations for a Definition and Categorization Framework for Plastic Debris

(2019) Nanna B. Hartmann et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

The gut mycobiota: insights into analysis, environmental interactions and role in gastrointestinal diseases

(2019) Mathias L. Richard et al.   Nature Reviews Gastroenterology & Hepatology

Uptake and effects of orally ingested polystyrene microplastic particles in vitro and in vivo

(2019) Valerie Stock et al.   ARCHIVES OF TOXICOLOGY

Microplastic pollution in commercial salt for human consumption: A review

(2019) Diogo Peixoto et al.   ESTUARINE COASTAL AND SHELF SCIENCE

Review of micro- and nanoplastic contamination in the food chain

(2019) Brigitte Toussaint et al.   Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment

Chromosome doubling of Sedum alfredii Hance: A novel approach for improving phytoremediation efficiency

(2019) Ying Feng et al.   JOURNAL OF ENVIRONMENTAL SCIENCES

Microplastics in freshwaters and drinking water: Critical review and assessment of data quality

(2019) Albert A. Koelmans et al.   WATER RESEARCH

Microbial Ecotoxicology of Marine Plastic Debris: A Review on Colonization and Biodegradation by the “Plastisphere”

(2019) Justine Jacquin et al.   Frontiers in Microbiology

Human Consumption of Microplastics

(2019) Kieran D. Cox et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Microplastics and the gut microbiome: How chronically exposed species may suffer from gut dysbiosis

(2019) Gloria Fackelmann et al.   MARINE POLLUTION BULLETIN

Adsorption behavior of organic pollutants and metals on micro/nanoplastics in the aquatic environment

(2019) Fei Yu et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Interaction between microplastics and microorganism as well as gut microbiota: A consideration on environmental animal and human health

(2019) Liang Lu et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Multi-endpoint toxicological assessment of polystyrene nano- and microparticles in different biological models in vitro

(2019) Michelle Hesler et al.   TOXICOLOGY IN VITRO

Simulating human exposure to indoor airborne microplastics using a Breathing Thermal Manikin

(2019) Alvise Vianello et al.   Scientific Reports

Propionate-Producing Consortium Restores Antibiotic-Induced Dysbiosis in a Dynamic in vitro Model of the Human Intestinal Microbial Ecosystem

(2019) Racha El Hage et al.   Frontiers in Microbiology

Detection of Various Microplastics in Human Stool

(2019) Philipp Schwabl et al.   ANNALS OF INTERNAL MEDICINE

Effects of microplastic particles and leaching additive on the life history and morphology of Daphnia magna

(2019) Isabella Schrank et al.   ENVIRONMENTAL POLLUTION

Plastic Teabags Release Billions of Microparticles and Nanoparticles into Tea

(2019) Laura M. Hernandez et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Sorption of sulfamethazine onto different types of microplastics: A combined experimental and molecular dynamics simulation study

(2019) Xuan Guo et al.   MARINE POLLUTION BULLETIN

Environmental occurrences, fate, and impacts of microplastics

(2019) Panfeng Wu et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Adsorbed Sulfamethoxazole Exacerbates the Effects of Polystyrene (∼2 μm) on Gut Microbiota and the Antibiotic Resistome of a Soil Collembolan

(2019) Qian Xiang et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Microplastics in the environment: A DPSIR analysis with focus on the responses

(2019) Mariana N. Miranda et al.   SCIENCE OF THE TOTAL ENVIRONMENT

2′-Fucosyllactose alters the composition and activity of gut microbiota from formula-fed infants receiving complementary feeding in a validated intestinal model

(2019) P. Van den Abbeele et al.   Journal of Functional Foods

Chlorine Dioxide Degradation Issues on Metal and Plastic Water Pipes Tested in Parallel in a Semi-Closed System

(2019) Alberto Vertova et al.   International Journal of Environmental Research and Public Health

Effect of weathering on environmental behavior of microplastics: Properties, sorption and potential risks

(2019) Peng Liu et al.   CHEMOSPHERE

Microplastics in house dust from 12 countries and associated human exposure

(2019) Junjie Zhang et al.   ENVIRONMENT INTERNATIONAL

The potential of microplastics as carriers of metals

(2019) V. Godoy et al.   ENVIRONMENTAL POLLUTION

Commensal E. coli rapidly transfer antibiotic resistance genes to human intestinal microbiota in the Mucosal Simulator of the Human Intestinal Microbial Ecosystem (M-SHIME)

(2019) Ellen Lambrecht et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

Microplastic serves as a potential vector for Cr in an in-vitro human digestive model

(2019) Yu-liang Liao et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Polyethylene microplastics affect the distribution of gut microbiota and inflammation development in mice

(2019) Boqing Li et al.   CHEMOSPHERE

Considerations on the use of equilibrium models for the characterisation of HOC-microplastic interactions in vector studies

(2018) Jorge F.M. Velez et al.   CHEMOSPHERE

Adsorption of antibiotics on microplastics

(2018) Jia Li et al.   ENVIRONMENTAL POLLUTION

Low levels of microplastics (MP) in wild mussels indicate that MP ingestion by humans is minimal compared to exposure via household fibres fallout during a meal

(2018) Ana I. Catarino et al.   ENVIRONMENTAL POLLUTION

Microplastic pollution increases gene exchange in aquatic ecosystems

(2018) Maria Arias-Andres et al.   ENVIRONMENTAL POLLUTION

An overview of chemical additives present in plastics: Migration, release, fate and environmental impact during their use, disposal and recycling

(2018) John N. Hahladakis et al.   JOURNAL OF HAZARDOUS MATERIALS

Spatial variability in the concentrations of metals in beached microplastics

(2018) M.C. Vedolin et al.   MARINE POLLUTION BULLETIN

Anthropogenic contamination of tap water, beer, and sea salt

(2018) Mary Kosuth et al.   PLoS One

Polystyrene microplastics induce gut microbiota dysbiosis and hepatic lipid metabolism disorder in mice

(2018) Liang Lu et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Microplastic and mesoplastic contamination in canned sardines and sprats

(2018) Ali Karami et al.   SCIENCE OF THE TOTAL ENVIRONMENT

A critical perspective on early communications concerning human health aspects of microplastics

(2018) Sinja Rist et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Decay of low-density polyethylene by bacteria extracted from earthworm's guts: A potential for soil restoration

(2018) Esperanza Huerta Lwanga et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Interaction of toxic chemicals with microplastics: A critical review

(2018) Fen Wang et al.   WATER RESEARCH

Protection from chemotherapy- and antibiotic-mediated dysbiosis of the gut microbiota by a probiotic with digestive enzymes supplement

(2018) Thomas E. Ichim et al.   Oncotarget

Microplastics Reduce Short-Term Effects of Environmental Contaminants. Part II: Polyethylene Particles Decrease the Effect of Polycyclic Aromatic Hydrocarbons on Microorganisms

(2018) Julia Kleinteich et al.   International Journal of Environmental Research and Public Health

MSPminer: abundance-based reconstitution of microbial pan-genomes from shotgun metagenomic data

(2018) Florian Plaza Oñate et al.   BIOINFORMATICS

Paradigms of Lung Microbiota Functions in Health and Disease, Particularly, in Asthma

(2018) Elliot Mathieu et al.   Frontiers in Physiology

Synthetic Polymer Contamination in Bottled Water

(2018) Sherri A. Mason et al.   Frontiers in Chemistry

Uptake of microplastics and related health effects: a critical discussion of Deng et al., Scientific reports 7:46687, 2017

(2018) Albert Braeuning   ARCHIVES OF TOXICOLOGY

Salivary and Gut Microbiomes Play a Significant Role in in Vitro Oral Bioaccessibility, Biotransformation, and Intestinal Absorption of Arsenic from Food

(2018) Marta Calatayud et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Sorption and desorption of selected pharmaceuticals by polyethylene microplastics

(2018) Roger Mamitiana Razanajatovo et al.   MARINE POLLUTION BULLETIN

Profiles of bacterial assemblages from microplastics of tropical coastal environments

(2018) Emily Curren et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Impacts of polystyrene microplastic on the gut barrier, microbiota and metabolism of mice

(2018) Yuanxiang Jin et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Plastics in the marine environment are reservoirs for antibiotic and metal resistance genes

(2018) Yuyi Yang et al.   ENVIRONMENT INTERNATIONAL

A first overview of textile fibers, including microplastics, in indoor and outdoor environments

(2017) Rachid Dris et al.   ENVIRONMENTAL POLLUTION

Temporal Dynamics of Bacterial and Fungal Colonization on Plastic Debris in the North Sea

(2017) Caroline De Tender et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Plastic and Human Health: A Micro Issue?

(2017) Stephanie L. Wright et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Tissue accumulation of microplastics in mice and biomarker responses suggest widespread health risks of exposure

(2017) Yongfeng Deng et al.   Scientific Reports

From macroplastic to microplastic: Degradation of high-density polyethylene, polypropylene, and polystyrene in a salt marsh habitat

(2016) John E. Weinstein et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Dangerous hitchhikers? Evidence for potentially pathogenic Vibrio spp. on microplastic particles

(2016) Inga V. Kirstein et al.   MARINE ENVIRONMENTAL RESEARCH

Increased EHEC survival and virulence gene expression indicate an enhanced pathogenicity upon simulated pediatric gastrointestinal conditions

(2016) Charlène Roussel et al.   PEDIATRIC RESEARCH

A microfluidics-based in vitro model of the gastrointestinal human–microbe interface

(2016) Pranjul Shah et al.   Nature Communications

Changes in Composition and Function of Human Intestinal Microbiota Exposed to Chlorpyrifos in Oil as Assessed by the SHIME® Model

(2016) Julie Reygner et al.   International Journal of Environmental Research and Public Health

Diversity and Activity of Communities Inhabiting Plastic Debris in the North Pacific Gyre

(2016) Jessica A. Bryant et al.   mSystems

Potential Health Impact of Environmentally Released Micro- and Nanoplastics in the Human Food Production Chain: Experiences from Nanotoxicology

(2015) Hans Bouwmeester et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Microplastics: addressing ecological risk through lessons learned

(2015) Kristian Syberg et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Contributions of microbiome and mechanical deformation to intestinal bacterial overgrowth and inflammation in a human gut-on-a-chip

(2015) Hyun Jung Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nano-plastics in the aquatic environment

(2015) K. Mattsson et al.   Environmental Science-Processes & Impacts

Micromanagement in the gut: microenvironmental factors govern colon mucosal biofilm structure and functionality

(2015) Rosemarie De Weirdt et al.   npj Biofilms and Microbiomes

The HMI™ module: a new tool to study the Host-Microbiota Interaction in the human gastrointestinal tract in vitro

(2014) Massimo Marzorati et al.   BMC MICROBIOLOGY

Evidence of Polyethylene Biodegradation by Bacterial Strains from the Guts of Plastic-Eating Waxworms

(2014) Jun Yang et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Microplastic is an Abundant and Distinct Microbial Habitat in an Urban River

(2014) Amanda McCormick et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Synthetic particles as contaminants in German beers

(2014) Gerd Liebezeit et al.   Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment

A standardised static in vitro digestion method suitable for food – an international consensus

(2014) M. Minekus et al.   Food & Function

Life in the “Plastisphere”: Microbial Communities on Plastic Marine Debris

(2013) Erik R. Zettler et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Survival of Escherichia coli O26:H11 exceeds that of Escherichia coli O157:H7 as assessed by simulated human digestion of contaminated raw milk cheeses

(2013) Stéphane D. Miszczycha et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

Biomolecular coronas provide the biological identity of nanosized materials

(2012) Marco P. Monopoli et al.   Nature Nanotechnology

Morphological aspects of interactions between microparticles and mammalian cells: intestinal uptake and onward movement

(2012) Katharine E. Carr et al.   PROGRESS IN HISTOCHEMISTRY AND CYTOCHEMISTRY

Oral drug delivery with polymeric nanoparticles: The gastrointestinal mucus barriers

(2011) Laura M. Ensign et al.   ADVANCED DRUG DELIVERY REVIEWS

Studying the host-microbiota interaction in the human gastrointestinal tract: basic concepts and in vitro approaches

(2011) Massimo Marzorati et al.   ANNALS OF MICROBIOLOGY

Adsorption of trace metals to plastic resin pellets in the marine environment

(2011) Luke A. Holmes et al.   ENVIRONMENTAL POLLUTION

Microplastics in the marine environment

(2011) Anthony L. Andrady   MARINE POLLUTION BULLETIN

Origin and fate of dietary nanoparticles and microparticles in the gastrointestinal tract

(2010) Jonathan J. Powell et al.   JOURNAL OF AUTOIMMUNITY

Early microbial biofilm formation on marine plastic debris

(2010) Delphine Lobelle et al.   MARINE POLLUTION BULLETIN

Comparison of a static and a dynamic in vitro model to estimate the bioaccessibility of As, Cd, Pb and Hg from food reference materials Fucus sp. (IAEA-140/TM) and Lobster hepatopancreas (TORT-2)

(2010) Silvia Torres-Escribano et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Biofilms

(2010) D. Lopez et al.   Cold Spring Harbor Perspectives in Biology

Transport and release of chemicals from plastics to the environment and to wildlife

(2009) E. L. Teuten et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES