Are mitochondria the main contributor of reactive oxygen species in cells?

Testing the shared‐pathway hypothesis in the carotenoid‐based coloration of red crossbills

(2020) Alejandro Cantarero et al.   EVOLUTION

Mitochondrial protein interaction landscape of SS-31

(2020) Juan D. Chavez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Small molecules as therapeutic drugs for Alzheimer's disease

(2019) Darryll M.A. Oliver et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Plumage redness signals mitochondrial function in the house finch

(2019) Geoffrey E. Hill et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Cytosolic ROS production by NADPH oxidase 2 regulates muscle glucose uptake during exercise

(2019) Carlos Henríquez-Olguin et al.   Nature Communications

The use of site-specific suppressors to measure the relative contributions of different mitochondrial sites to skeletal muscle superoxide and hydrogen peroxide production

(2019) Renata L.S. Goncalves et al.   Redox Biology

Migratory flight imposes oxidative stress in bats

(2018) David Costantini et al.   Current Zoology

Life History Trade-offs within the Context of Mitochondrial Hormesis

(2018) W R Hood et al.   INTEGRATIVE AND COMPARATIVE BIOLOGY

The mitochondrially targeted antioxidant MitoQ protects the intestinal barrier by ameliorating mitochondrial DNA damage via the Nrf2/ARE signaling pathway

(2018) Qiongyuan Hu et al.   Cell Death & Disease

Migratory flight imposes oxidative stress in bats

(2018) David Costantini et al.   Current Zoology

Mitochondrial and cytosolic sources of hydrogen peroxide in resting C2C12 myoblasts

(2018) Hoi-Shan Wong et al.   FREE RADICAL BIOLOGY AND MEDICINE

A comparative and evolutionary approach to oxidative stress in fish: A review

(2017) Kim Birnie-Gauvin et al.   FISH AND FISHERIES

The Physiology of Exercise in Free-Living Vertebrates: What Can We Learn from Current Model Systems?

(2017) Kang Nian Yap et al.   INTEGRATIVE AND COMPARATIVE BIOLOGY

Production of superoxide and hydrogen peroxide from specific mitochondrial sites under different bioenergetic conditions

(2017) Hoi-Shan Wong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A radical shift in perspective: mitochondria as regulators of reactive oxygen species

(2017) Daniel Munro et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Hydrogen peroxide as a central redox signaling molecule in physiological oxidative stress: Oxidative eustress

(2017) Helmut Sies   Redox Biology

Using the MitoB method to assess levels of reactive oxygen species in ecological studies of oxidative stress

(2017) Karine Salin et al.   Scientific Reports

Nitroxides catalytically inhibit nitrite oxidation and heme inactivation induced by H 2 O 2 , nitrite and metmyoglobin or methemoglobin

(2016) Amram Samuni et al.   FREE RADICAL BIOLOGY AND MEDICINE

Therapeutic inhibition of mitochondrial reactive oxygen species with mito-TEMPO reduces diabetic cardiomyopathy

(2016) Rui Ni et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondrial generation of superoxide and hydrogen peroxide as the source of mitochondrial redox signaling

(2016) Martin D. Brand   FREE RADICAL BIOLOGY AND MEDICINE

Current versus future reproduction and longevity: a re-evaluation of predictions and mechanisms

(2016) Yufeng Zhang et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Xanthine Oxidoreductase-Derived Reactive Species: Physiological and Pathological Effects

(2016) Maria Giulia Battelli et al.   Oxidative Medicine and Cellular Longevity

Role of ROS and RNS Sources in Physiological and Pathological Conditions

(2016) Sergio Di Meo et al.   Oxidative Medicine and Cellular Longevity

Neuroprotective properties of mitochondria-targeted antioxidants of the SkQ-type

(2016) Nickolay K. Isaev et al.   REVIEWS IN THE NEUROSCIENCES

Oxidative stress and life histories: unresolved issues and current needs

(2015) John R. Speakman et al.   Ecology and Evolution

Scavenging of H2O2 by mouse brain mitochondria

(2014) Anatoly A. Starkov et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS

(2014) Edward T. Chouchani et al.   NATURE

Oxidative stress as a cost of reproduction: Beyond the simplistic trade-off model

(2013) John R. Speakman et al.   BIOESSAYS

Recent advances in reactive oxygen species measurement in biological systems

(2013) J.F. Woolley et al.   TRENDS IN BIOCHEMICAL SCIENCES

Studies of Mitochondrial and Nonmitochondrial Sources Implicate Nicotinamide Adenine Dinucleotide Phosphate Oxidase(s) in the Increased Skeletal Muscle Superoxide Generation That Occurs During Contractile Activity

(2012) Giorgos Konstantinos Sakellariou et al.   ANTIOXIDANTS & REDOX SIGNALING

Native rates of superoxide production from multiple sites in isolated mitochondria measured using endogenous reporters

(2012) Casey L. Quinlan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Oxidative damage, ageing, and life-history evolution: where now?

(2012) Colin Selman et al.   TRENDS IN ECOLOGY & EVOLUTION

The free-radical damage theory: Accumulating evidence against a simple link of oxidative stress to ageing and lifespan

(2011) John R. Speakman et al.   BIOESSAYS

Measurement of H2O2 within Living Drosophila during Aging Using a Ratiometric Mass Spectrometry Probe Targeted to the Mitochondrial Matrix

(2011) Helena M. Cochemé et al.   Cell Metabolism

Measuring reactive oxygen and nitrogen species with fluorescent probes: challenges and limitations

(2011) Balaraman Kalyanaraman et al.   FREE RADICAL BIOLOGY AND MEDICINE

The Mitochondria-Targeted Antioxidant MitoQ Prevents Loss of Spatial Memory Retention and Early Neuropathology in a Transgenic Mouse Model of Alzheimer's Disease

(2011) M. J. McManus et al.   JOURNAL OF NEUROSCIENCE

There is no evidence that mitochondria are the main source of reactive oxygen species in mammalian cells

(2011) Guy C. Brown et al.   MITOCHONDRION

Regulation of reactive oxygen species generation in cell signaling

(2011) Yun Soo Bae et al.   MOLECULES AND CELLS

The Role of Mitochondria in Reactive Oxygen Species Metabolism and Signaling

(2010) Anatoly A. Starkov   Annals of the New York Academy of Sciences

Animal and human studies with the mitochondria-targeted antioxidant MitoQ

(2010) Robin A.J. Smith et al.   Annals of the New York Academy of Sciences

Hydrogen peroxide efflux from muscle mitochondria underestimates matrix superoxide production - a correction using glutathione depletion

(2010) Jason R. Treberg et al.   FEBS Journal

Tissue-, substrate-, and site-specific characteristics of mitochondrial reactive oxygen species generation

(2009) Erich B. Tahara et al.   FREE RADICAL BIOLOGY AND MEDICINE

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

Oxidative stress as a mediator of life history trade-offs: mechanisms, measurements and interpretation

(2008) Pat Monaghan et al.   ECOLOGY LETTERS

The mitochondria-targeted antioxidant MitoQ protects against organ damage in a lipopolysaccharide–peptidoglycan model of sepsis

(2008) Damon A. Lowes et al.   FREE RADICAL BIOLOGY AND MEDICINE

A mitochondria-targeted nitroxide is reduced to its hydroxylamine by ubiquinol in mitochondria

(2008) Jan Trnka et al.   FREE RADICAL BIOLOGY AND MEDICINE

Exercise-Induced Oxidative Stress: Cellular Mechanisms and Impact on Muscle Force Production

(2008) Scott K. Powers et al.   PHYSIOLOGICAL REVIEWS