Astragaloside IV inhibits protein tyrosine phosphatase 1B and improves insulin resistance in insulin-resistant HepG2 cells and triglyceride accumulation in oleic acid (OA)-treated HepG2 cells

Docking- and pharmacophore-based virtual screening for the identification of novel Mycobacterium tuberculosis protein tyrosine phosphatase B (MptpB) inhibitor with a thiobarbiturate scaffold

(2019) Dongfeng Zhang et al.   BIOORGANIC CHEMISTRY

Pharmacophore-based drug design for potential AChE inhibitors from Traditional Chinese Medicine Database

(2018) Yingying Jiang et al.   BIOORGANIC CHEMISTRY

Camellia euphlebia flower extract inhibits oleic acid-induced lipid accumulation via reduction of lipogenesis in HepG2 cells

(2018) Dongye He et al.   European Journal of Integrative Medicine

A novel PTP1B inhibitor extracted from Ganoderma lucidum ameliorates insulin resistance by regulating IRS1-GLUT4 cascades in the insulin signaling pathway

(2018) Zhou Yang et al.   Food & Function

EGCG evokes Nrf2 nuclear translocation and dampens PTP1B expression to ameliorate metabolic misalignment under insulin resistance condition

(2018) Yashi Mi et al.   Food & Function

Research review on the pharmacological effects of astragaloside IV

(2016) Lei Li et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Astragaloside IV facilitates glucose transport in C2C12 myotubes through the IRS1/AKT pathway and suppresses the palmitate-induced activation of the IKK/IκBα pathway

(2016) RONGFENG ZHU et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Effect of Astragalus membranaceus (Fisch) Bunge extract on streptozocin-induced diabetic in rats

(2016) Mei-ling Huo et al.   TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH

Sasa quelpaertensisandp-Coumaric Acid Attenuate Oleic Acid-Induced Lipid Accumulation in HepG2 Cells

(2013) Jeong-Hwan KIM et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Dock/Nck facilitates PTP61F/PTP1B regulation of insulin signalling

(2011) Chia-Lun Wu et al.   BIOCHEMICAL JOURNAL

PTP1B inhibitor improves both insulin resistance and lipid abnormalities in vivo and in vitro

(2011) Yi-ming Ma et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Astragaloside IV Improves Metabolic Syndrome and Endothelium Dysfunction in Fructose-Fed Rats

(2011) Ning Zhang et al.   MOLECULES

PTP1B: a double agent in metabolism and oncogenesis

(2010) Shu-Chin Yip et al.   TRENDS IN BIOCHEMICAL SCIENCES

Effect of astragaloside IV on hepatic glucose-regulating enzymes in diabetic mice induced by a high-fat diet and streptozotocin

(2009) Lin Lv et al.   PHYTOTHERAPY RESEARCH

Tannins present in Cichorium intybus enhance glucose uptake and inhibit adipogenesis in 3T3-L1 adipocytes through PTP1B inhibition

(2008) V.S. Muthusamy et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Astragaloside IV attenuates lipolysis and improves insulin resistance induced by TNFαin 3T3-L1 adipocytes

(2008) Boren Jiang et al.   PHYTOTHERAPY RESEARCH