Buxuhuayu Decoction Accelerates Angiogenesis by Activating the PI3K-Akt-eNOS Signalling Pathway in a Streptozotocin-Induced Diabetic Ulcer Rat Model

A network pharmacology approach to explore the potential targets underlying the effect of sinomenine on rheumatoid arthritis

(2020) Xiang Guo et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

An In situ Collagen‐HA Hydrogel System Promotes Survival and Preserves the Proangiogenic Secretion of hiPSC‐derived Vascular Smooth Muscle Cells

(2020) Biraja C. Dash et al.   BIOTECHNOLOGY AND BIOENGINEERING

A multi-scale systems pharmacology approach uncovers the anti-cancer molecular mechanism of Ixabepilone

(2020) Dong-Sheng Cao et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Metabolic syndrome and peripheral neuropathy

(2020) Mohamed Kazamel et al.   MUSCLE & NERVE

Multipotent adult progenitor cells grown under xenobiotic-free conditions support vascularization during wound healing

(2020) Bart Vaes et al.   Stem Cell Research & Therapy

Dissecting the mechanism of Yuzhi Zhixue granule on ovulatory dysfunctional uterine bleeding by network pharmacology and molecular docking

(2020) Jialin Li et al.   Chinese Medicine

Prevalence and Risk Factors for Diabetic Peripheral Neuropathy in Type 2 Diabetic Patients From 14 Countries: Estimates of the INTERPRET-DD Study

(2020) Yanhui Lu et al.   Frontiers in Public Health

Improving Chronic Diabetic Wound Healing through an Injectable and Self-Healing Hydrogel with Platelet-Rich Plasma Release

(2020) Zhiyong Qian et al.   ACS Applied Materials & Interfaces

Phytotherapy for wound healing: The most important herbal plants in wound healing based on Iranian etnobotanical documents

(2020) Kamal Solati et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Mechanisms of Compound Kushen Injection for the Treatment of Lung Cancer Based on Network Pharmacology

(2019) Ziqi Meng et al.   Evidence-based Complementary and Alternative Medicine

SwissTargetPrediction: updated data and new features for efficient prediction of protein targets of small molecules

(2019) Antoine Daina et al.   NUCLEIC ACIDS RESEARCH

Uncovering the pharmacological mechanism of Carthamus tinctorius L. on cardiovascular disease by a systems pharmacology approach

(2019) Guohua Yu et al.   BIOMEDICINE & PHARMACOTHERAPY

Lespedeza cuneata protects the endothelial dysfunction via eNOS phosphorylation of PI3K/Akt signaling pathway in HUVECs

(2018) Jae Hyuk Lee et al.   PHYTOMEDICINE

Exploring the Mechanism of Dangguiliuhuang Decoction Against Hepatic Fibrosis by Network Pharmacology and Experimental Validation

(2018) Hui Cao et al.   Frontiers in Pharmacology

Netrin-1 restores cell injury and impaired angiogenesis in vascular endothelial cells upon high glucose by PI3K/AKT-eNOS

(2017) Ying Xing et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

OUP accepted manuscript

(2017)   NUCLEIC ACIDS RESEARCH

Diabetic foot ulcer management in clinical practice in the UK: costs and outcomes

(2017) Julian F Guest et al.   International Wound Journal

Androgen receptor regulated microRNA miR-182-5p promotes prostate cancer progression by targeting the ARRDC3/ITGB4 pathway

(2016) Jingjing Yao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

DisGeNET: a comprehensive platform integrating information on human disease-associated genes and variants

(2016) Janet Piñero et al.   NUCLEIC ACIDS RESEARCH

Increased expression of endosomal members of toll-like receptor family abrogates wound healing in patients with type 2 diabetes mellitus

(2015) Kanhaiya Singh et al.   International Wound Journal

AMP-activated protein kinase activators in diabetic ulcers: from animal studies to Phase II drugs under investigation

(2014) Jiun-Tsai Lin et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Effect of low-intensity direct current on expression of vascular endothelial growth factor and nitric oxide in diabetic foot ulcers

(2014) Mohammad Reza Mohajeri-Tehrani et al.   JOURNAL OF REHABILITATION RESEARCH AND DEVELOPMENT

Human symptoms–disease network

(2014) XueZhong Zhou et al.   Nature Communications

TCMSP: a database of systems pharmacology for drug discovery from herbal medicines

(2014) Jinlong Ru et al.   Journal of Cheminformatics

Topological analysis and interactive visualization of biological networks and protein structures

(2012) Nadezhda T Doncheva et al.   Nature Protocols

Akt signalling in health and disease

(2011) Ingeborg Hers et al.   CELLULAR SIGNALLING

Cytoscape Web: an interactive web-based network browser

(2010) Christian T. Lopes et al.   BIOINFORMATICS

Is Oral Administration of Chinese Herbal Medicine Effective and Safe as an Adjunctive Therapy for Managing Diabetic Foot Ulcers? A Systematic Review and Meta-Analysis

(2010) Min Chen et al.   JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE

An Ezrin/Calpain/PI3K/AMPK/eNOS s1179 Signaling Cascade Mediating VEGF-Dependent Endothelial Nitric Oxide Production

(2008) Ji-Youn Youn et al.   CIRCULATION RESEARCH

Age-dependent impairment of HIF-1α expression in diabetic mice: Correction with electroporation-facilitated gene therapy increases wound healing, angiogenesis, and circulating angiogenic cells

(2008) Lixin Liu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

In vitroantidiabetic activities of five medicinal herbs used in Chinese medicinal formulae

(2008) C. H. Lau et al.   PHYTOTHERAPY RESEARCH