Brahma‐Related Gene‐1 (BRG1) promotes the malignant phenotype of glioblastoma cells

Immune and genomic correlates of response to anti-PD-1 immunotherapy in glioblastoma

(2019) Junfei Zhao et al.   NATURE MEDICINE

MicroRNA-1 suppresses glioblastoma in preclinical models by targeting fibronectin

(2019) Chuan He Yang et al.   CANCER LETTERS

CXCL9, CXCL10, CXCL11/CXCR3 axis for immune activation – A target for novel cancer therapy

(2018) Ryuma Tokunaga et al.   CANCER TREATMENT REVIEWS

Identification of thioredoxin-interacting protein (TXNIP) as a downstream target for IGF1 action

(2018) Karthik Nagaraj et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The critical role that STAT3 plays in glioma-initiating cells: STAT3 addiction in glioma

(2018) Debolina Ganguly et al.   Oncotarget

High expression of SMARCA4 or SMARCA2 is frequently associated with an opposite prognosis in cancer

(2018) Jose A. Guerrero-Martínez et al.   Scientific Reports

Chromatin remodeling factor BRG1 regulates stemness and chemosensitivity of glioma initiating cells

(2018) Debolina Ganguly et al.   STEM CELLS

BRG1 promotes VEGF-A expression and angiogenesis in human colorectal cancer cells

(2017) Jingqin Lan et al.   EXPERIMENTAL CELL RESEARCH

Dominant-negative SMARCA4 mutants alter the accessibility landscape of tissue-unrestricted enhancers

(2017) H. Courtney Hodges et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

TXNIP overexpression suppresses proliferation and induces apoptosis in SMMC7221 cells through ROS generation and MAPK pathway activation

(2017) Jian Li et al.   ONCOLOGY REPORTS

mTOR and HDAC Inhibitors Converge on the TXNIP/Thioredoxin Pathway to Cause Catastrophic Oxidative Stress and Regression of RAS-Driven Tumors

(2017) Clare F. Malone et al.   Cancer Discovery

Dominant-negative SMARCA4 mutants alter the accessibility landscape of tissue-unrestricted enhancers

(2017) H. Courtney Hodges et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

MicroRNA203a suppresses glioma tumorigenesis through an ATM-dependent interferon response pathway

(2017) Chuan He Yang et al.   Oncotarget

The role of the SWI/SNF chromatin remodeling complex in maintaining the stemness of glioma initiating cells

(2017) Hiroaki Hiramatsu et al.   Scientific Reports

Cancer stem cell metabolism: a potential target for cancer therapy

(2016) Abhijeet Deshmukh et al.   Molecular Cancer

GlioVis data portal for visualization and analysis of brain tumor expression datasets

(2016) Robert L. Bowman et al.   NEURO-ONCOLOGY

MiRNA203 suppresses the expression of protumorigenic STAT1 in glioblastoma to inhibit tumorigenesis

(2016) Chuan He Yang et al.   Oncotarget

Brg1 promotes both tumor-suppressive and oncogenic activities at distinct stages of pancreatic cancer formation

(2015) Nilotpal Roy et al.   GENES & DEVELOPMENT

SMARCA4 inactivation defines a group of undifferentiated thoracic malignancies transcriptionally related to BAF-deficient sarcomas

(2015) Francois Le Loarer et al.   NATURE GENETICS

Metabolic reprogramming in triple-negative breast cancer through Myc suppression of TXNIP

(2015) Liangliang Shen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mammalian SWI/SNF chromatin remodeling complexes and cancer: Mechanistic insights gained from human genomics

(2015) C. Kadoch et al.   Science Advances

Essential role of BRG, the ATPase subunit of BAF chromatin remodeling complexes, in leukemia maintenance

(2014) M. Buscarlet et al.   BLOOD

BRG1 promotes chemoresistance of pancreatic cancer cells through crosstalking with Akt signalling

(2014) Xiaoran Liu et al.   EUROPEAN JOURNAL OF CANCER

MicroRNA-21 Promotes Glioblastoma Tumorigenesis by Down-regulating Insulin-like Growth Factor-binding Protein-3 (IGFBP3)

(2014) Chuan He Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

BRG1 promotes the repair of DNA double-strand breaks by facilitating the replacement of RPA with RAD51

(2014) W. Qi et al.   JOURNAL OF CELL SCIENCE

Transcriptional Repression by the BRG1-SWI/SNF Complex Affects the Pluripotency of Human Embryonic Stem Cells

(2014) Xiaoli Zhang et al.   Stem Cell Reports

The Somatic Genomic Landscape of Glioblastoma

(2013) Cameron W. Brennan et al.   CELL

Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation

(2013) J. Shi et al.   GENES & DEVELOPMENT

Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy

(2013) Cigall Kadoch et al.   NATURE GENETICS

The Spectrum of SWI/SNF Mutations, Ubiquitous in Human Cancers

(2013) A. Hunter Shain et al.   PLoS One

Swi/Snf chromatin remodeling/tumor suppressor complex establishes nucleosome occupancy at target promoters

(2013) M. Y. Tolstorukov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mapping the Hallmarks of Lung Adenocarcinoma with Massively Parallel Sequencing

(2012) Marcin Imielinski et al.   CELL

Downregulation of SWI/SNF chromatin remodeling factor subunits modulates cisplatin cytotoxicity

(2012) Anbarasi Kothandapani et al.   EXPERIMENTAL CELL RESEARCH

Silencing of Irf7 pathways in breast cancer cells promotes bone metastasis through immune escape

(2012) Bradley N Bidwell et al.   NATURE MEDICINE

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

A miR-21 hairpin structure-based gene knockdown vector

(2010) Junming Yue et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

SWI/SNF Deficiency Results in Aberrant Chromatin Organization, Mitotic Failure, and Diminished Proliferative Capacity

(2009) Ryan J. Bourgo et al.   MOLECULAR BIOLOGY OF THE CELL

An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency

(2009) L. Ho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting Interleukin 6 Signaling Suppresses Glioma Stem Cell Survival and Tumor Growth

(2009) Hui Wang et al.   STEM CELLS

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE

SWI/SNF-Brg1 Regulates Self-Renewal and Occupies Core Pluripotency-Related Genes in Embryonic Stem Cells

(2008) Benjamin L. Kidder et al.   STEM CELLS