Carbon Nanotubes: Smart Drug/Gene Delivery Carriers

Endocytosis: The Nanoparticle and Submicron Nanocompounds Gateway into the Cell

(2020) Darío Manzanares et al.   Pharmaceutics

Natural halloysite nanotubes /chitosan based bio-nanocomposite for delivering norfloxacin, an anti-microbial agent in sustained release manner

(2020) Mrinmoy Barman et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Multi-walled carbon nanotube oxidation dependent keratinocyte cytotoxicity and skin inflammation

(2019) Brian C. Palmer et al.   Particle and Fibre Toxicology

Chloroplast-selective gene delivery and expression in planta using chitosan-complexed single-walled carbon nanotube carriers

(2019) Seon-Yeong Kwak et al.   Nature Nanotechnology

Enhanced Lysosomal Escape of pH-Responsive Polyethylenimine–Betaine Functionalized Carbon Nanotube for the Codelivery of Survivin Small Interfering RNA and Doxorubicin

(2019) Yue Cao et al.   ACS Applied Materials & Interfaces

Facile synthesis of multiwalled carbon nanotube via folic acid grafted nanoparticle for precise delivery of doxorubicin

(2019) Sameer Lakade et al.   IET Nanobiotechnology

A Single-Crystal Open-Capsule Metal–Organic Framework

(2019) Yong-Sheng Wei et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A novel PEGylated carbon nanotube conjugated mangiferin: An explorative nanomedicine for brain cancer cells

(2019) P.J. Harsha et al.   JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY

αVβ3-Targeted delivery of camptothecin-encapsulated CNT-cyclic RGD in 2D and 3D cancer cell culture

(2019) Byumseok Koh et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Phototherapy using immunologically modified carbon nanotubes to potentiate checkpoint blockade for metastatic breast cancer

(2019) Yong Li et al.   Nanomedicine-Nanotechnology Biology and Medicine

Mannose‐Modified Multi‐Walled Carbon Nanotubes as a Delivery Nanovector Optimizing the Antigen Presentation of Dendritic Cells

(2019) Zhipeng Dong et al.   ChemistryOpen

Multi-Drug/Gene NASH Therapy Delivery and Selective Hyperspectral NIR Imaging Using Chirality-Sorted Single-Walled Carbon Nanotubes

(2019) Md. Tanvir Hasan et al.   Cancers

Carbon nanotube-based DNA vaccine against koi herpesvirus given by intramuscular injection

(2019) Feng Hu et al.   FISH & SHELLFISH IMMUNOLOGY

Metal-Organic Framework (MOF) Nanorods, Nanotubes, and Nanowires

(2018) Roberto C. Arbulu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Size-dependent cell uptake of carbon nanotubes by macrophages: A comparative and quantitative study

(2018) Minfang Zhang et al.   CARBON

Magnetofluorescent Fe 3 O 4 /carbon quantum dots coated single-walled carbon nanotubes as dual-modal targeted imaging and chemo/photodynamic/photothermal triple-modal therapeutic agents

(2018) Ming Zhang et al.   CHEMICAL ENGINEERING JOURNAL

Molecular dynamics simulation strategies for designing carbon-nanotube-based targeted drug delivery

(2018) Mohammed N. Al-Qattan et al.   DRUG DISCOVERY TODAY

Effective deactivation of A549 tumor cells in vitro and in vivo by RGD-decorated chitosan-functionalized single-walled carbon nanotube loading docetaxel

(2018) Bin Li et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Development of a promising drug delivery for formononetin: Cyclodextrin-modified single-walled carbon nanotubes

(2018) Xiaohong Liu et al.   JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY

Toxicity of Doxorubicin (Dox) to different experimental organ systems

(2018) Arivalagan Pugazhendhi et al.   LIFE SCIENCES

Ultrasonic-assisted fabrication of starch/MWCNT-glucose nanocomposites for drug delivery

(2018) Shadpour Mallakpour et al.   ULTRASONICS SONOCHEMISTRY

Surface modified halloysite nanotubes: A flexible interface for biological, environmental and catalytic applications

(2018) Maithri Tharmavaram et al.   ADVANCES IN COLLOID AND INTERFACE SCIENCE

The nano-bio interaction and biomedical applications of carbon nanomaterials

(2018) Xuejing Cui et al.   CARBON

Rho GTPases in A549 and Caco-2 cells dominating the endocytic pathways of nanocarbons with different morphologies

(2018) Siyang Song et al.   International Journal of Nanomedicine

Composite material based on hydroxyapatite and multi-walled carbon nanotubes filled by iron: Preparation, properties and drug release ability

(2018) L.B. Sukhodub et al.   Materials Science & Engineering C-Materials for Biological Applications

Influence of Carbon Nanotubes and Its Derivatives on Tumor Cells In Vitro and Biochemical Parameters, Cellular Blood Composition In Vivo

(2018) Olena M. Perepelytsina et al.   Nanoscale Research Letters

Conjugation of a GM3 lactone mimetic on carbon nanotubes enhances the related inhibition of melanoma-associated metastatic events

(2018) Paolo Arosio et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Different aggregation and shape characteristics of carbon materials affect biological responses in RAW264 cells

(2018) Chika Kuroda et al.   International Journal of Nanomedicine

Advances in Carbon Nanotubes for Malignant Melanoma: A Chance for Treatment

(2018) Elidamar Nunes de Carvalho Lima et al.   Molecular Diagnosis & Therapy

Photoactivatable RNAi for cancer gene therapy triggered by near-infrared-irradiated single-walled carbon nanotubes

(2017) Xueling Ren et al.   International Journal of Nanomedicine

Photothermal therapy of melanoma tumor using multiwalled carbon nanotubes

(2017) Zahra sobhani et al.   International Journal of Nanomedicine

Effects of major parameters of nanoparticles on their physical and chemical properties and recent application of nanodrug delivery system in targeted chemotherapy

(2017) Jing Zhang et al.   International Journal of Nanomedicine

Polyethylenimine-functionalized carbon nanotubes tagged with AS1411 aptamer for combination gene and drug delivery into human gastric cancer cells

(2017) Sahar Taghavi et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Multiwalled carbon nanotubes for drug delivery: Efficiency related to length and incubation time

(2017) Niccolò Sciortino et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Functionalized single-walled carbon nanotubes: cellular uptake, biodistribution and applications in drug delivery

(2017) Zixian Li et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Regeneration of arsenic spent adsorbents by Fe/MgO nanoparticles

(2017) Konstantinos Simeonidis et al.   JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY

Ex vivo and in vivo performance of anti-cancer drug loaded carbon nanotubes

(2017) Priyanka Sharma et al.   JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY

Chitosan-folate decorated carbon nanotubes for site specific lung cancer delivery

(2017) Rahul Pratap Singh et al.   Materials Science & Engineering C-Materials for Biological Applications

Encapsulation of methotrexate and cyclophosphamide in interpolymer complexes formed between poly acrylic acid and poly ethylene glycol on multi-walled carbon nanotubes as drug delivery systems

(2017) Mohammad Hossein Ahmadi Azqhandi et al.   Materials Science & Engineering C-Materials for Biological Applications

Carbon nanotube as a carrier in drug delivery system for carnosine dipeptide: A computer simulation study

(2017) Sepideh Ketabi et al.   Materials Science & Engineering C-Materials for Biological Applications

Carbon nanotubes in microfluidic lab-on-a-chip technology: current trends and future perspectives

(2017) Amir Ghasemi et al.   Microfluidics and Nanofluidics

Surface chemistry of carbon nanoparticles functionally select their uptake in various stages of cancer cells

(2017) Indrajit Srivastava et al.   Nano Research

Nanotubular topography enhances the bioactivity of titanium implants

(2017) Jingyan Huang et al.   Nanomedicine-Nanotechnology Biology and Medicine

Spatially-resolved profiling of carbon nanotube uptake across cell lines

(2017) H. D. Summers et al.   Nanoscale

PEGylated anticancer-carbon nanotubes complex targeting mitochondria of lung cancer cells

(2017) Sang-Woo Kim et al.   NANOTECHNOLOGY

Phosphatidylserine targeted single-walled carbon nanotubes for photothermal ablation of bladder cancer

(2017) Needa A Virani et al.   NANOTECHNOLOGY

Photothermal-triggered control of sub-cellular drug accumulation using doxorubicin-loaded single-walled carbon nanotubes for the effective killing of human breast cancer cells

(2017) Yunok Oh et al.   NANOTECHNOLOGY

Development and characterization of PLA-mPEG copolymer containing iron nanoparticle-coated carbon nanotubes for controlled delivery of Docetaxel

(2017) Farshid Hossein Panahi et al.   POLYMER

Effects of charge and surface defects of multi-walled carbon nanotubes on the disruption of model cell membranes

(2017) Wei Jiang et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Evaluation of multiwalled carbon nanotube cytotoxicity in cultures of human brain microvascular endothelial cells grown on plastic or basement membrane

(2017) Brittany N. Eldridge et al.   TOXICOLOGY IN VITRO

Evaluation of chemical modification effects on DNA plasmid transfection efficiency of single-walled carbon nanotube–succinate– polyethylenimine conjugates as non-viral gene carriers

(2017) Azadeh Hashem Nia et al.   MedChemComm

Efficacy and tolerability of nanoparticle albumin-bound paclitaxel in combination with carboplatin as a late-phase chemotherapy for recurrent and advanced non-small-cell lung cancer: A multi-center study of the Fukushima lung cancer association group of surgeons

(2017) Mitsunori Higuchi et al.   Oncology Letters

Length-dependent intracellular bundling of single-walled carbon nanotubes influences retention

(2017) Sumin Jin et al.   Journal of Materials Chemistry B

Polymer cloaking modulates the carbon nanotube protein corona and delivery into cancer cells

(2017) Januka Budhathoki-Uprety et al.   Journal of Materials Chemistry B

Nanomaterials modulate stem cell differentiation: biological interaction and underlying mechanisms

(2017) Min Wei et al.   JOURNAL OF NANOBIOTECHNOLOGY

The adverse vascular effects of multi-walled carbon nanotubes (MWCNTs) to human vein endothelial cells (HUVECs) in vitro: role of length of MWCNTs

(2017) Jimin Long et al.   JOURNAL OF NANOBIOTECHNOLOGY

Carbon nanotubes as nanovectors for intracellular delivery of laronidase in Mucopolysaccharidosis type I

(2017) T. Da Ros et al.   Nanoscale

Length effects on the dynamic process of cellular uptake and exocytosis of single-walled carbon nanotubes in murine macrophage cells

(2017) Xuejing Cui et al.   Scientific Reports

Carbon Nanomaterials and DNA: from Molecular Recognition to Applications

(2016) Hanjun Sun et al.   ACCOUNTS OF CHEMICAL RESEARCH

Lentinan-Modified Carbon Nanotubes as an Antigen Delivery System Modulate Immune Response in Vitro and in Vivo

(2016) Jie Xing et al.   ACS Applied Materials & Interfaces

Near-Infrared Light Activation of Proteins Inside Living Cells Enabled by Carbon Nanotube-Mediated Intracellular Delivery

(2016) He Li et al.   ACS Applied Materials & Interfaces

Translocation of Functionalized Multi-Walled Carbon Nanotubes across Human Pulmonary Alveolar Epithelium: Dominant Role of Epithelial Type 1 Cells

(2016) Pakatip Ruenraroengsak et al.   ACS Nano

Toward carbon nanotube-based imaging agents for the clinic

(2016) Mayra Hernández-Rivera et al.   BIOMATERIALS

Fibrin-targeting peptide CREKA-conjugated multi-walled carbon nanotubes for self-amplified photothermal therapy of tumor

(2016) Bo Zhang et al.   BIOMATERIALS

Functional long circulating single walled carbon nanotubes for fluorescent/photoacoustic imaging-guided enhanced phototherapy

(2016) Lisi Xie et al.   BIOMATERIALS

Diameter size and aspect ratio as critical determinants of uptake, stress response, global metabolomics and epigenetic alterations in multi-wall carbon nanotubes

(2016) Nivedita Chatterjee et al.   CARBON

Smart micro/nanoparticles in stimulus-responsive drug/gene delivery systems

(2016) Mahdi Karimi et al.   CHEMICAL SOCIETY REVIEWS

Biological effects of agglomerated multi-walled carbon nanotubes

(2016) Zheng-Mei Song et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Preparation and evaluation of polyethylenimine-functionalized carbon nanotubes tagged with 5TR1 aptamer for targeted delivery of Bcl-xL shRNA into breast cancer cells

(2016) Sahar Taghavi et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Stimuli-responsive lipid nanotubes in gel formulations for the delivery of doxorubicin

(2016) Sibel Ilbasmis-Tamer et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

A comparative study on the in vitro cytotoxic responses of two mammalian cell types to fullerenes, carbon nanotubes and iron oxide nanoparticles

(2016) Çiğdem Dönmez Güngüneş et al.   DRUG AND CHEMICAL TOXICOLOGY

Systemic distribution of single-walled carbon nanotubes in a novel model: alteration of biochemical parameters, metabolic functions, liver accumulation, and inflammation in vivo

(2016) Douglas M Noonan et al.   International Journal of Nanomedicine

Carbon nanotubes as cancer therapeutic carriers and mediators

(2016) Kuk Hui Son et al.   International Journal of Nanomedicine

Carbon nanotubes from synthesis to in vivo biomedical applications

(2016) Muhammad Imran Sajid et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Carbon nanotubes' surface chemistry determines their potency as vaccine nanocarriers in vitro and in vivo

(2016) Hatem A.F.M. Hassan et al.   JOURNAL OF CONTROLLED RELEASE

Functionalised carbon nanotubes: From intracellular uptake and cell-related toxicity to systemic brain delivery

(2016) Pedro M. Costa et al.   JOURNAL OF CONTROLLED RELEASE

Carbon Nanotubes in Biomedical Applications: Factors, Mechanisms, and Remedies of Toxicity

(2016) Reem Alshehri et al.   JOURNAL OF MEDICINAL CHEMISTRY

Effects of Multiwalled Carbon Nanotube Surface Modification and Purification on Bovine Serum Albumin Binding and Biological Responses

(2016) Wei Bai et al.   Journal of Nanomaterials

In vivo drug delivery of gemcitabine with PEGylated single-walled carbon nanotubes

(2016) Ali Razzazan et al.   Materials Science & Engineering C-Materials for Biological Applications

Targeted delivery and controlled release of Paclitaxel for the treatment of lung cancer using single-walled carbon nanotubes

(2016) Baodan Yu et al.   Materials Science & Engineering C-Materials for Biological Applications

Conjugation of Docetaxel with Multiwalled Carbon Nanotubes and Codelivery with Piperine: Implications on Pharmacokinetic Profile and Anticancer Activity

(2016) Kaisar Raza et al.   MOLECULAR PHARMACEUTICS

A Comparative Study on the Alterations of Endocytic Pathways in Multiple Lysosomal Storage Disorders

(2016) Jeff Rappaport et al.   MOLECULAR PHARMACEUTICS

Nanotechnology in diagnosis and treatment of coronary artery disease

(2016) Mahdi Karimi et al.   Nanomedicine

The impact of nanoparticle protein corona on cytotoxicity, immunotoxicity and target drug delivery

(2016) Claudia Corbo et al.   Nanomedicine

Regulation of angiogenesis through the efficient delivery of microRNAs into endothelial cells using polyamine-coated carbon nanotubes

(2016) Andrea Masotti et al.   Nanomedicine-Nanotechnology Biology and Medicine

Antimicrobial molecular nanocarrier–drug conjugates

(2016) Andrzej S. Skwarecki et al.   Nanomedicine-Nanotechnology Biology and Medicine

Interactions and effects of BSA-functionalized single-walled carbon nanotubes on different cell lines

(2016) Laura Muzi et al.   NANOTECHNOLOGY

Unraveling the architecture of caveolae

(2016) Robert G. Parton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-Efficiency Gene Transfection of Cells through Carbon Nanotube Arrays

(2016) Masoud Golshadi et al.   Small

Smart Carbon Nanotubes with Laser-Controlled Behavior in Gene Delivery and Therapy through a Non-Digestive Trafficking Pathway

(2016) Fenfen Kong et al.   Small

ROS-generating TiO2 nanoparticles for non-invasive sonodynamic therapy of cancer

(2016) Dong Gil You et al.   Scientific Reports

Multiwalled Carbon Nanotubes Inhibit Tumor Progression in a Mouse Model

(2016) Lorena García-Hevia et al.   Advanced Healthcare Materials

Highly Selective Photothermal Therapy by a Phenoxylated-Dextran-Functionalized Smart Carbon Nanotube Platform

(2016) Seungmin Han et al.   Advanced Healthcare Materials

α-Galactosidase-A Loaded-Nanoliposomes with Enhanced Enzymatic Activity and Intracellular Penetration

(2016) Ingrid Cabrera et al.   Advanced Healthcare Materials

Polyionic complex of single-walled carbon nanotubes and PEG-grafted-hyperbranched polyethyleneimine (PEG-PEI-SWNT) for an improved doxorubicin loading and delivery: development and in vitro characterization

(2016) Fakhrossadat Farvadi et al.   Artificial Cells Nanomedicine and Biotechnology

Different chemical strategies to aminate oxidised multi-walled carbon nanotubes for siRNA complexation and delivery

(2016) Cinzia Spinato et al.   Journal of Materials Chemistry B

The “click-on-tube” approach for the production of efficient drug carriers based on oxidized multi-walled carbon nanotubes

(2016) Stefano Fedeli et al.   Journal of Materials Chemistry B

Toxicity mechanism in fetal lung fibroblast cells for multi-walled carbon nanotubes defined by chemical impurities and dispersibility

(2016) Aparna Shinde et al.   Toxicology Research

Photothermal Therapy of Glioblastoma Multiforme Using Multiwalled Carbon Nanotubes Optimized for Diffusion in Extracellular Space

(2016) Brittany N. Eldridge et al.   ACS Biomaterials-Science & Engineering

Photothermal Therapy of Glioblastoma Multiforme Using Multiwalled Carbon Nanotubes Optimized for Diffusion in Extracellular Space

(2016) Brittany N. Eldridge et al.   ACS Biomaterials Science & Engineering

Efficient delivery of DNA into bovine preimplantation embryos by multiwall carbon nanotubes

(2016) Michele Munk et al.   Scientific Reports

Cell Membrane Proteins Modulate the Carbon Nanotube Optical Bandgap via Surface Charge Accumulation

(2015) Daniel Roxbury et al.   ACS Nano

The interaction of carbon nanotubes with an in vitro blood-brain barrier model and mouse brain in vivo

(2015) Houmam Kafa et al.   BIOMATERIALS

Carbon Nanomaterials for Biological Imaging and Nanomedicinal Therapy

(2015) Guosong Hong et al.   CHEMICAL REVIEWS

Carbon nanotubes part I: preparation of a novel and versatile drug-delivery vehicle

(2015) Mahdi Karimi et al.   Expert Opinion on Drug Delivery

Evaluation of uptake, cytotoxicity and inflammatory effects in respiratory cells exposed to pristine and -OH and -COOH functionalized multi-wall carbon nanotubes

(2015) Cinzia Lucia Ursini et al.   JOURNAL OF APPLIED TOXICOLOGY

Carbon nanotube biosensors

(2015) Carmen-Mihaela Tîlmaciu et al.   Frontiers in Chemistry

Carbon nanotubes in hyperthermia therapy

(2013) Ravi Singh et al.   ADVANCED DRUG DELIVERY REVIEWS

The safety and efficacy of peginesatide in patients with CKD

(2013) Kai-Uwe Eckardt   Nature Reviews Nephrology

Peginesatide for Anemia in Patients with Chronic Kidney Disease Not Receiving Dialysis

(2013) Iain C. Macdougall et al.   NEW ENGLAND JOURNAL OF MEDICINE

Culture medium type affects endocytosis of multi-walled carbon nanotubes in BEAS-2B cells and subsequent biological response

(2013) Hisao Haniu et al.   TOXICOLOGY IN VITRO

Long-term biopersistence of tangled oxidized carbon nanotubes inside and outside macrophages in rat subcutaneous tissue

(2013) Yoshinori Sato et al.   Scientific Reports

 v Integrins in Angiogenesis and Cancer

(2013) S. M. Weis et al.   Cold Spring Harbor Perspectives in Medicine

Carbon Nanotubes: Applications in Pharmacy and Medicine

(2013) Hua He et al.   Biomed Research International

Translocation mechanisms of chemically functionalised carbon nanotubes across plasma membranes

(2012) Lara Lacerda et al.   BIOMATERIALS

The targeted delivery of anticancer drugs to brain glioma by PEGylated oxidized multi-walled carbon nanotubes modified with angiopep-2

(2012) Jinfeng Ren et al.   BIOMATERIALS

Lipid Bilayers Covalently Anchored to Carbon Nanotubes

(2012) Yasaman Dayani et al.   LANGMUIR

Characterization of carbon nanotube protein corona by using quantitative proteomics

(2012) Xiaoning Cai et al.   Nanomedicine-Nanotechnology Biology and Medicine

Electrically controlled drug release from nanostructured polypyrrole coated on titanium

(2011) Sirinrath Sirivisoot et al.   NANOTECHNOLOGY

Binding of blood proteins to carbon nanotubes reduces cytotoxicity

(2011) C. Ge et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional motor recovery from brain ischemic insult by carbon nanotube-mediated siRNA silencing

(2011) K. T. Al-Jamal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Trafficking and Subcellular Localization of Multiwalled Carbon Nanotubes in Plant Cells

(2010) Maged F. Serag et al.   ACS Nano

New Insights of Transmembranal Mechanism and Subcellular Localization of Noncovalently Modified Single-Walled Carbon Nanotubes

(2010) Feifan Zhou et al.   NANO LETTERS

Repeated administrations of carbon nanotubes in male mice cause reversible testis damage without affecting fertility

(2010) Yuhong Bai et al.   Nature Nanotechnology

Cell Response to Carbon Nanotubes: Size-Dependent Intracellular Uptake Mechanism and Subcellular Fate

(2010) Bin Kang et al.   Small

Preparation and Cellular Uptake of pH-Dependent Fluorescent Single-Wall Carbon Nanotubes

(2009) Xiaoke Zhang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Cancer-Cell Targeting and Photoacoustic Therapy Using Carbon Nanotubes as “Bomb” Agents

(2009) Bin Kang et al.   Small

Lectins modulate multi-walled carbon nanotubes cellular uptake in human epidermal keratinocytes

(2009) Leshuai W. Zhang et al.   TOXICOLOGY IN VITRO

Intracellular uptake, trafficking and subcellular distribution of folate conjugated single walled carbon nanotubes within living cells

(2008) Bin Kang et al.   NANOTECHNOLOGY

A pilot toxicology study of single-walled carbon nanotubes in a small sample of mice

(2008) Meike L. Schipper et al.   Nature Nanotechnology