The History and Mystery of Alveolar Epithelial Type II Cells: Focus on Their Physiologic and Pathologic Role in Lung

Second-generation lung-on-a-chip with an array of stretchable alveoli made with a biological membrane

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The Three-Dimensional Ultrastructure of the Human Alveolar Epithelium Revealed by Focused Ion Beam Electron Microscopy

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Alveolar Epithelial Type II Cells as Drivers of Lung Fibrosis in Idiopathic Pulmonary Fibrosis

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Understanding Lineage Plasticity as a Path to Targeted Therapy Failure in EGFR-Mutant Non-small Cell Lung Cancer

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Thoughts on the alveolar phase of COVID-19

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Inflammatory Signals Induce AT2 Cell-Derived Damage-Associated Transient Progenitors that Mediate Alveolar Regeneration

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Persistence of a regeneration-associated, transitional alveolar epithelial cell state in pulmonary fibrosis

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Alveolar regeneration through a Krt8+ transitional stem cell state that persists in human lung fibrosis

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WNT1-inducible-signaling pathway protein 1 regulates the development of kidney fibrosis through the TGF-β1 pathway

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Contributions of alveolar epithelial cell quality control to pulmonary fibrosis

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Capillary cell-type specialization in the alveolus

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STAT3–BDNF–TrkB signalling promotes alveolar epithelial regeneration after lung injury

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Prolonged Low-Dose Methylprednisolone in Patients With Severe COVID-19 Pneumonia

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A molecular cell atlas of the human lung from single-cell RNA sequencing

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Study of the common activating mechanism of apoptosis and epithelial-to-mesenchymal transition in alveolar type II epithelial cells

(2020) Jiali Wang et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Generation of lung organoids from human pluripotent stem cells in vitro

(2019) Alyssa J. Miller et al.   Nature Protocols

Cellular Senescence as a Mechanism and Target in Chronic Lung Diseases

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On the Topological Complexity of Human Alveolar Epithelial Type 1 Cells

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Correlation between circulating fibrocytes and dermal thickness in limited cutaneous systemic sclerosis patients: a pilot study

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Alveolar Type 2 Epithelial Cells as Potential Therapeutics for Acute Lung Injury/Acute Respiratory Distress Syndrome

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New Insights into the Immune Molecular Regulation of the Pathogenesis of Acute Respiratory Distress Syndrome

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Single-cell Wnt signaling niches maintain stemness of alveolar type 2 cells

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A review of inflammatory mechanism in airway diseases

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Muc5b overexpression causes mucociliary dysfunction and enhances lung fibrosis in mice

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The lung is a site of platelet biogenesis and a reservoir for haematopoietic progenitors

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Novel translational approaches to the search for precision therapies for acute respiratory distress syndrome

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Clinical trials in acute respiratory distress syndrome: challenges and opportunities

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Targeted Type 2 Alveolar Cell Depletion. A Dynamic Functional Model for Lung Injury Repair

(2016) Orquidea Garcia et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Developmental origin of lung macrophage diversity

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Epithelial sodium channel (ENaC) family: Phylogeny, structure–function, tissue distribution, and associated inherited diseases

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Epithelial to mesenchymal transition-related proteins ZEB1, β-catenin and β-tubulin-III in idiopathic pulmonary fibrosis

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MAPK-Mediated YAP Activation Controls Mechanical-Tension-Induced Pulmonary Alveolar Regeneration

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On the Tricks Alveolar Epithelial Cells Play to Make a Good Lung

(2015) Ewald R. Weibel   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The innate immune function of airway epithelial cells in inflammatory lung disease

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Mice with Pulmonary Fibrosis Driven by Telomere Dysfunction

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Alveolar type II cells maintain bioenergetic homeostasis in hypoxia through metabolic and molecular adaptation

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Revealing the Pathogenic and Aging-related Mechanisms of the Enigmatic Idiopathic Pulmonary Fibrosis. An Integral Model

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Type 2 alveolar cells are stem cells in adult lung

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Lung regeneration and translational implications of the postpneumonectomy model

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Genetic variants associated with idiopathic pulmonary fibrosis susceptibility and mortality: a genome-wide association study

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The Alveolar Epithelium Determines Susceptibility to Lung Fibrosis in Hermansky-Pudlak Syndrome

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Pathogenesis of chronic obstructive pulmonary disease

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Directed differentiation of human pluripotent stem cells into mature airway epithelia expressing functional CFTR protein

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Alveolar Type II Cells Possess the Capability of Initiating Lung Tumor Development

(2012) Chuwen Lin et al.   PLoS One

Innate Immunity in the Respiratory Epithelium

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The three R’s of lung health and disease: repair, remodeling, and regeneration

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Involvement of type II pneumocytes in the pathogenesis of chronic obstructive pulmonary disease

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Reconstituting Organ-Level Lung Functions on a Chip

(2010) D. Huh et al.   SCIENCE

Targeted Injury of Type II Alveolar Epithelial Cells Induces Pulmonary Fibrosis

(2009) Thomas H. Sisson et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE