Review
Plant Sciences
Zhicheng Jiao, Huan Du, Shu Chen, Wei Huang, Liangfa Ge
Summary: Adapting to the gravitational field is crucial for terrestrial plants to thrive on Earth. The LAZY gene family has been identified as a key player in the early stages of gravity signaling, ensuring proper auxin redistribution for both roots and shoots upon gravistimulation. Research on LAZY genes has significantly advanced our understanding of plant gravitropism and revealed new molecular details of early gravitropism events.
FRONTIERS IN PLANT SCIENCE
(2021)
Article
Plant Sciences
Despina Samakovli, Loukia Roka, Anastasia Dimopoulou, Panagiota Konstantinia Plitsi, Asta Zukauskaite, Paraskevi Georgopoulou, Ondrej Novak, Dimitra Milioni, Polydefkis Hatzopoulos
Summary: HSP90 plays a crucial role in regulating auxin distribution and signaling in plants, affecting root growth, gravity response, and lateral root formation. The depletion of HSP90 results in distorted polar distribution of auxin and impaired root gravitropism, highlighting the essential role of HSP90 in auxin homeostasis during plant development.
Review
Plant Sciences
Huibin Han, Maciek Adamowski, Linlin Qi, Saqer S. Alotaibi, Jiri Friml
Summary: Plants exhibit differential growth responses through the coordination of auxin hormone and PIN auxin exporters during tropisms, which are regulated by environmental stimuli. Auxin gradients promote cell elongation and bending, with auxin feedback playing a crucial role in PIN polarity during bending termination. Interactions between different tropisms are reviewed to enhance understanding of plant adaptive growth in the natural environment.
Article
Biochemistry & Molecular Biology
Jing Xia, Mengjuan Kong, Zhisen Yang, Lianghanxiao Sun, Yakun Peng, Yanbo Mao, Hong Wei, Wei Ying, Yongxiang Gao, Jiri Friml, Jianping Weng, Xin Liu, Linfeng Sun, Shutang Tan
Summary: This study reveals that naproxen, an anti-inflammatory drug, acts as an auxin transport inhibitor in plants. It suppresses auxin transport by targeting PIN-mediated auxin efflux. This discovery provides insights into the molecular mechanisms of PIN-mediated auxin transport and has potential applications in plant biology and agriculture.
PLANT COMMUNICATIONS
(2023)
Article
Genetics & Heredity
An-Pei Zhou, Yuan-Yuan Zhong, Si-Qi Li, Xuan Fei, Pei-Hua Gan, Dan Zong, Cheng-Zhong He
Summary: The polar auxin transport system plays a crucial role in the response to inversion in Populus species, with different expression patterns among the PIN, AUX/LAX and ABCB gene families in different species.
Article
Biochemistry & Molecular Biology
Shiv Mani Dubey, Soeun Han, Nathan Stutzman, Michael J. Prigge, Eva Medvecka, Matthieu Pierre Platre, Wolfgang Busch, Matyas Fendrych, Mark Estelle
Summary: The phytohormone auxin triggers root growth inhibition within seconds via a non-transcriptional pathway. The AFB1 protein plays a crucial role in this rapid response, and its N-terminal region, including the F-box domain and residues contributing to auxin binding, is essential for its specific function. A substitution of the N-terminal region of AFB1 disrupts its cytoplasmic localization and activity in rapid root growth inhibition. Moreover, AFB1 is involved in calcium influx triggered by auxin and negatively regulates lateral root formation and transcription of auxin-induced genes.
Article
Plant Sciences
Tom J. Fisher, Eduardo Flores-Sandoval, John P. Alvarez, John L. Bowman
Summary: This study provides the first characterization of PIN proteins in the liverwort Marchantia polymorpha. The MpPIN1 protein is localized in the plasma membrane and plays essential roles in plant growth and development, including the regulation of leaf and flower development. These findings contribute to our understanding of signal transduction and directional growth in plant development.
Article
Multidisciplinary Sciences
Lindy Abas, Martina Kolb, Johannes Stadlmann, Dorina P. Janacek, Kristina Lukic, Claus Schwechheimer, Leonid A. Sazanov, Lukas Mach, Jiri Friml, Ulrich Z. Hammes
Summary: NPA is a key inhibitor of directional auxin transport in plants, acting by directly inhibiting PINs. Research also shows an effect of NPA on PIN dimerization, offering insights into structural aspects of PINs related to their transport mechanism.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Plant Sciences
Narender Kumar, Chloe Caldwell, Anjali S. Iyer-Pascuzzi
Summary: The root cap plays critical roles in root growth, protecting the root meristem and influencing soil penetration, as well as perceiving and transmitting environmental signals for root branching patterns. However, the mechanism by which the root cap integrates endogenous developmental pathways with environmental signals remains unclear. This study demonstrates that the transcription factor NLP7 links nitrate signaling with auxin pathways to regulate root cap development in Arabidopsis. NLP7 is involved in the release of root cap cells under low nitrate conditions and impacts auxin pathways in the last layer of the root cap. Mutations in NLP7 affect the expression of auxin carriers and transcription factors that regulate auxin transport. Overall, NLP7 acts as a key regulator in integrating nitrate signaling and endogenous auxin pathways for root cap development.
JOURNAL OF EXPERIMENTAL BOTANY
(2023)
Article
Biochemistry & Molecular Biology
Shunkai Hu, Xinqiu Liu, Wei Xuan, Huiling Mei, Jianjie Li, Xuan Chen, Zhen Zhao, Yuxin Zhao, Anburaj Jeyaraj, Rajiv Periakaruppan, Xing -Hui Li
Summary: Auxin affects various aspects of plant growth and development. This study identified 8 CslPIN and 10 CslPILS genes in tea plants and analyzed their properties and expressions. The role of CslPIN3 in root growth and auxin accumulation was studied through overexpression in Arabidopsis and hybridization in tea plants, confirming its involvement in root development regulation. This study provides valuable insights into the regulatory mechanisms of CslPIN and CslPILS genes in the formation of adventitious roots in tea plants.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Multidisciplinary Sciences
Qingqing Wang, Marco Marconi, Chunmei Guan, Krzysztof Wabnik, Yuling Jiao
Summary: The flattened leaf form is crucial for efficient photosynthesis, and recent studies have shown that communication between the shoot apical meristem (SAM) and leaf primordia, mediated by polar auxin transport (PAT), plays a role in leaf blade formation. This research combines experimental observations and computer model simulations to demonstrate that microsurgical incisions and local inhibition of PAT in tomato can interfere with auxin transport, resulting in altered leaf blade shape. The study also reveals the role of auxin patterning and gene expression in leaf formation.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Biochemistry & Molecular Biology
Tingting Shen, Ning Jia, Shanshan Wei, Wenyan Xu, Tingting Lv, Jiaoteng Bai, Bing Li
Summary: The mitochondria-localized heat shock protein mtHSC70-1 in Arabidopsis plays a crucial role in regulating root development and growth through the modulation of reactive oxygen species homeostasis and polar auxin transport.
Article
Biochemistry & Molecular Biology
Krisztina Otvos, Marco Marconi, Andrea Vega, Jose O'Brien, Alexander Johnson, Rashed Abualia, Livio Antonielli, Juan Carlos Montesinos, Yuzhou Zhang, Shutang Tan, Candela Cuesta, Christina Artner, Eleonore Bouguyon, Alain Gojon, Jiri Friml, Rodrigo A. Gutierrez, Krzysztof Wabnik, Eva Benkova
Summary: The availability of nitrogen in soil is crucial for plant growth, where plants have evolved different strategies to sense and respond to heterogeneous nitrogen distribution. The coordination of root growth in response to different nitrogen sources involves modulation of root system architecture and auxin flux between tissue layers. This study provides mechanistic insights into the dynamic mechanisms of root growth in response to nitrogen sources, with implications for agricultural productivity.
Article
Plant Sciences
Deok Hyun Seo, Haewon Jeong, Yang Do Choi, Geupil Jang
Summary: The root endodermis forms a selective barrier to prevent solute diffusion into the vasculature by depositing hydrophobic compounds in cell walls to form the Casparian strip. Auxin plays a key role in regulating the division of root endodermal cells, while PGP1 and PGP19 are involved in this regulation by mediating auxin flow.
Article
Biochemistry & Molecular Biology
Fabrizio Araniti, Emanuela Talarico, Maria Letizia Madeo, Eleonora Greco, Marco Minervino, Sara Alvarez-Rodriguez, Antonella Muto, Michele Ferrari, Adriana Chiappetta, Leonardo Bruno
Summary: This study investigates the mechanisms underlying the phytotoxicity of Cadmium (Cd) on Arabidopsis thaliana. The results reveal that Cd inhibits primary root elongation by affecting cell expansion in the meristem zone. Cd also alters Auxin accumulation and affects the polar transporters PINs, particularly PIN2. Additionally, high Cd concentration induces accumulation of reactive oxygen species (ROS) in roots, resulting in altered microtubules organization, starch and sucrose metabolism, and gravitropic root response.
Article
Plant Sciences
Christian Loefke, David Scheuring, Kai Duenser, Maria Schoeller, Christian Luschnig, Juergen Kleine-Vehn
JOURNAL OF EXPERIMENTAL BOTANY
(2015)
Article
Multidisciplinary Sciences
Rene Benjamins, Elke Barbez, Martina Ortbauer, Inez Terpstra, Doris Lucyshyn, Jeanette Moulinier-Anzola, Muhammad Asaf Khan, Johannes Leitner, Nenad Malenica, Haroon Butt, Barbara Korbei, Ben Scheres, Juergen Kleine-Vehn, Christian Luschnig
SCIENTIFIC REPORTS
(2016)
Article
Biochemistry & Molecular Biology
Katarzyna Retzer, Jozef Lacek, Roman Skokan, Charo I. del Genio, Stanislav Vosolsobe, Martina Lankova, Katerina Malinska, Nataliia Konstantinova, Eva Zazimalova, Richard M. Napier, Jan Petrasek, Christian Luschnig
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2017)
Review
Plant Sciences
Michelle Gallei, Christian Luschnig, Jiri Friml
CURRENT OPINION IN PLANT BIOLOGY
(2020)
Article
Biochemistry & Molecular Biology
Jeanette Moulinier-Anzola, Maximilian Schwihla, Lucinda De-Araujo, Christina Artner, Lisa Joerg, Nataliia Konstantinova, Christian Luschnig, Barbara Korbei
Article
Multidisciplinary Sciences
Katarzyna Retzer, Maria Akhmanova, Nataliia Konstantinova, Katerina Malinska, Johannes Leitner, Jan Petrasek, Christian Luschnig
NATURE COMMUNICATIONS
(2019)
Article
Biochemistry & Molecular Biology
Katarzyna Retzer, Jeanette Moulinier-Anzola, Rebecca Lugsteiner, Nataliia Konstantinova, Maximilian Schwihla, Barbara Korbei, Christian Luschnig
Summary: Intracellular sorting and abundance of plasma membrane proteins are crucial for plants to sense and respond to environmental inputs. The reversible covalent modification by ubiquitin plays a key role in inducing adjustments in protein localization and functionality. The RING DOMAIN LIGASE family, including RGLG1, has been implicated in endocytic vacuolar cargo sorting, and this study provides evidence for their role in cargo trafficking between plasma membrane and endosomal compartments.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Multidisciplinary Sciences
Nataliia Konstantinova, Lukas Hoermayer, Matous Glanc, Rabab Keshkeih, Shutang Tan, Martin Di Donato, Katarzyna Retzer, Jeanette Moulinier-Anzola, Max Schwihla, Barbara Korbei, Markus Geisler, Jiri Friml, Christian Luschnig
Summary: The authors of this study reveal the involvement of WAV3 E3 ubiquitin ligases in determining the polarity of PIN proteins in Arabidopsis. They show that WAV3 E3 ligases selectively antagonize the ectopic deposition of newly synthesized PIN proteins, maintaining the polar localization of PIN proteins.
NATURE COMMUNICATIONS
(2022)