Inhibition of miR-494-3p alleviates oxidative stress-induced cell senescence and inflammation in the primary epithelial cells of COPD patients

MiR-494 acts as a tumor promoter by targeting CASP2 in non-small cell lung cancer

(2019) Qiao Zhang et al.   Scientific Reports

Systemic Markers of Inflammation in Smokers With Symptoms Despite Preserved Spirometry in SPIROMICS

(2019) Suresh Garudadri et al.   CHEST

miR-145-5p is associated with smoke-related chronic obstructive pulmonary disease via targeting KLF5

(2019) Xiaomin Dang et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Cellular Senescence as a Mechanism and Target in Chronic Lung Diseases

(2019) Peter J Barnes et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

ROS-Dependent Calpain Activation Contributes to Airway and Pulmonary Vascular Remodeling in COPD

(2019) Jing Zhu et al.   ANTIOXIDANTS & REDOX SIGNALING

MicroRNAs in COPD: small molecules with big potential

(2019) Brian D. Hobbs et al.   EUROPEAN RESPIRATORY JOURNAL

Dysregulated autophagy in COPD: A pathogenic process to be deciphered

(2019) W.S. Daniel Tan et al.   PHARMACOLOGICAL RESEARCH

Role of miRNA-181a-2-3p in cadmium-induced inflammatory responses of human bronchial epithelial cells

(2019) Jeeyoung Kim et al.   Journal of Thoracic Disease

Chronic Obstructive Pulmonary Disease and Smoking Status — United States, 2017

(2019) Anne G. Wheaton et al.   MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

MicroRNA miR-31 targets SIRT3 to disrupt mitochondrial activity and increase oxidative stress in oral carcinoma

(2019) Yu-Yu Kao et al.   CANCER LETTERS

MicroRNA-206 promotes lipopolysaccharide-induced inflammation injury via regulation of IRAK1 in MRC-5 cells

(2019) Heying Chu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Small airway fibrosis in COPD

(2019) Peter J. Barnes   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Experimental model of temporomandibular joint arthritis: evaluation of contralateral joint and masticatory muscles

(2018) George Azevedo Lemos et al.   ARCHIVES OF ORAL BIOLOGY

The Role of Computed Tomography for the Evaluation of Lung Disease in Alpha-1 Antitrypsin Deficiency

(2018) Michael A. Campos et al.   CHEST

NLRP3 inflammasome mediates chronic intermittent hypoxia-induced renal injury implication of the microRNA-155/FOXO3a signaling pathway

(2018) Xu Wu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

miR-494-3p modulates the progression of in vitro and in vivo Parkinson’s disease models by targeting SIRT3

(2018) Lijiao Geng et al.   NEUROSCIENCE LETTERS

Sirtuin3 protects aged human mesenchymal stem cells against oxidative stress and enhances efficacy of cell therapy for ischaemic heart diseases

(2018) Dong-Yang Zhang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Serum from patients with chronic obstructive pulmonary disease induces senescence-related phenotype in bronchial epithelial cells

(2018) Barbara Kuźnar-Kamińska et al.   Scientific Reports

Sirtuin3 Protected Against Neuronal Damage and Cycled into Nucleus in Status Epilepticus Model

(2018) Inja Cho et al.   MOLECULAR NEUROBIOLOGY

Protective effects of metformin against osteoarthritis through upregulation of SIRT3-mediated PINK1/Parkin-dependent mitophagy in primary chondrocytes

(2018) Chenzhong Wang et al.   BioScience Trends

The roles of microRNAs in the pathogenesis of chronic obstructive pulmonary disease

(2018) Xinwei Huang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

AMP-activated protein kinase reduces inflammatory responses and cellular senescence in pulmonary emphysema

(2017) Xiao-Yu Cheng et al.   Oncotarget

A Novel Role for SIRT3 in Regulating Mediators Involved in the Terminal Pathways of Human Labor and Delivery

(2016) R. Lim et al.   BIOLOGY OF REPRODUCTION

Liraglutide ameliorates non-alcoholic fatty liver disease by enhancing mitochondrial architecture and promoting autophagy through the SIRT1/SIRT3-FOXO3a pathway

(2016) Wenxin Tong et al.   HEPATOLOGY RESEARCH

MicroRNA-340 promotes the tumor growth of human gastric cancer by inhibiting cyclin G2

(2016) Guozhi Yin et al.   ONCOLOGY REPORTS

Oxidative stress dependent microRNA-34a activation via PI3Kα reduces the expression of sirtuin-1 and sirtuin-6 in epithelial cells

(2016) J. R. Baker et al.   Scientific Reports

The daily rhythms of mitochondrial gene expression and oxidative stress regulation are altered by aging in the mouse liver

(2015) Changxia Gong et al.   CHRONOBIOLOGY INTERNATIONAL

Risk factors and early origins of chronic obstructive pulmonary disease

(2015) Dirkje S Postma et al.   LANCET

Senescence-Associated Secretory Phenotype and Its Possible Role in Chronic Obstructive Pulmonary Disease

(2014) Manish Kumar et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

SIRT3 overexpression antagonizes high glucose accelerated cellular senescence in human diploid fibroblasts via the SIRT3–FOXO1 signaling pathway

(2013) Bin Zhang et al.   AGE

c-Myc Regulates Proliferation and Fgf10 Expression in Airway Smooth Muscle after Airway Epithelial Injury in Mouse

(2013) Thomas Volckaert et al.   PLoS One

Activity of sputum p38 MAPK is correlated with airway inflammation and reduced FEV1 in COPD patients

(2013) Hui Gao   MEDICAL SCIENCE MONITOR

Oxidative Stress and Chromatin Remodeling in Chronic Obstructive Pulmonary Disease and Smoking-Related Diseases

(2012) Isaac K. Sundar et al.   ANTIOXIDANTS & REDOX SIGNALING