Phosphoglycerate dehydrogenase (PHGDH) inhibitors: a comprehensive review 2015-2020

Unravelling the Allosteric Targeting of PHGDH at the ACT-Binding Domain with a Photoactivatable Diazirine Probe and Mass Spectrometry Experiments

(2021) Quentin Spillier et al.   MOLECULES

Presymptomatic Increase of an Extracellular RNA in Blood Plasma Associates with the Development of Alzheimer’s Disease

(2020) Zhangming Yan et al.   CURRENT BIOLOGY

PHGDH is an independent prognosis marker and contributes cell proliferation, migration and invasion in human pancreatic cancer

(2018) Zhiwang Song et al.   GENE

Overcoming erlotinib resistance in EGFR mutation-positive lung adenocarcinomas through repression of phosphoglycerate dehydrogenase

(2018) Jiang-Kai Dong et al.   Theranostics

Structural insights into the enzymatic activity and potential substrate promiscuity of human 3-phosphoglycerate dehydrogenase (PHGDH)

(2017) Judith E. Unterlass et al.   Oncotarget

The Emerging Hallmarks of Cancer Metabolism

(2016) Natalya N. Pavlova et al.   Cell Metabolism

The importance of serine metabolism in cancer

(2016) Katherine R. Mattaini et al.   JOURNAL OF CELL BIOLOGY

Expression of serine/glycine metabolism-related proteins is different according to the thyroid cancer subtype

(2016) Woo Young Sun et al.   Journal of Translational Medicine

p73 regulates serine biosynthesis in cancer

(2013) I Amelio et al.   ONCOGENE

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Functional genomics reveal that the serine synthesis pathway is essential in breast cancer

(2011) Richard Possemato et al.   NATURE

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE