Involvement of the NLRC4 inflammasome in promoting retinal ganglion cell death in an acute glaucoma mouse model

AIM2 inflammasome surveillance of DNA damage shapes neurodevelopment

(2020) Catherine R. Lammert et al.   NATURE

Adeno Associated Virus (AAV) as a Tool for Clinical and Experimental Delivery of Target Genes into the Mammalian Retina

(2019) Tesshu Hori et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

NLRC4 inflammasome activation regulated by TNF-α promotes inflammatory responses in nonalcoholic fatty liver disease

(2019) Yihe Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

NOD‐like receptor C4 Inflammasome Regulates the Growth of Colon Cancer Liver Metastasis in NAFLD

(2019) Koichiro Ohashi et al.   HEPATOLOGY

IL-1α and IL-1β promote NOD2-induced immune responses by enhancing MAPK signaling

(2019) Sushan Li et al.   LABORATORY INVESTIGATION

Vascular protection of salicin on IL-1β-induced endothelial inflammatory response and damages in retinal endothelial cells

(2019) Yu Song et al.   Artificial Cells Nanomedicine and Biotechnology

Variants in NLRP3 and NLRC4 inflammasome associate with susceptibility and severity of multiple sclerosis

(2019) Jaine LS Soares et al.   Multiple Sclerosis and Related Disorders

NLRP3 inflammasome as a potential treatment in ischemic stroke concomitant with diabetes

(2019) Pu Hong et al.   Journal of Neuroinflammation

Astrocytic p38α MAPK drives NMDA receptor-dependent long-term depression and modulates long-term memory

(2019) Marta Navarrete et al.   Nature Communications

The BRCC3 regulated by Cdk5 promotes the activation of neuronal NLRP3 inflammasome in Parkinson’s disease models

(2019) Xinyu Cheng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Nepetin inhibits IL-1β induced inflammation via NF-κB and MAPKs signaling pathways in ARPE-19 cells

(2018) Xi Chen et al.   BIOMEDICINE & PHARMACOTHERAPY

Microglia in the Retina: Roles in Development, Maturity, and Disease

(2018) Sean M. Silverman et al.   Annual Review of Vision Science

Evidence that NLRC4 Inflammasome Mediates Apoptotic and Pyroptotic Microglial Death Following Ischemic Stroke

(2018) Luting Poh et al.   BRAIN BEHAVIOR AND IMMUNITY

Neuroprotection of retinal ganglion cells by a novel gene therapy construct that achieves sustained enhancement of brain-derived neurotrophic factor/tropomyosin-related kinase receptor-B signaling

(2018) Andrew Osborne et al.   Cell Death & Disease

Interaction between microglia and retinal pigment epithelial cells determines the integrity of outer blood-retinal barrier in diabetic retinopathy

(2018) Dong Hyun Jo et al.   GLIA

Neuroprotective effects of overexpressed microRNA-200a on activation of glaucoma-related retinal glial cells and apoptosis of ganglion cells via downregulating FGF7-mediated MAPK signaling pathway

(2018) Hui Peng et al.   CELLULAR SIGNALLING

Adeno-Associated Viral Vector 2 and 9 Transduction Is Enhanced in Streptozotocin-Induced Diabetic Mouse Retina

(2018) Si Hyung Lee et al.   Molecular Therapy-Methods & Clinical Development

Gene therapy for inherited retinal and optic nerve degenerations

(2017) Nicholas A. Moore et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

The NLRC4 Inflammasome

(2017) Joseph A. Duncan et al.   IMMUNOLOGICAL REVIEWS

Role of microglia in ischemic focal stroke and recovery: focus on Toll-like receptors

(2017) Jenni E. Anttila et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

P16INK4a upregulation mediated by TBK1 induces retinal ganglion cell senescence in ischemic injury

(2017) L u Li et al.   Cell Death & Disease

JNK inhibitor alleviates apoptosis of fetal neural stem cells induced by emulsified isoflurane

(2017) Lei Zhou et al.   Oncotarget

Cdk5-Dependent Activation of Neuronal Inflammasomes in Parkinson's Disease

(2016) Pei Zhang et al.   MOVEMENT DISORDERS

AIM2 and NLRC4 inflammasomes contribute with ASC to acute brain injury independently of NLRP3

(2015) Adam Denes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Preference for concentric orientations in the mouse superior colliculus

(2015) Mehran Ahmadlou et al.   Nature Communications

The Pathophysiology and Treatment of Glaucoma

(2014) Robert N. Weinreb et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Factors Influencing the Retrograde Labeling of Retinal Ganglion Cells with Fluorogold in an Animal Optic Nerve Crush Model

(2014) Tzu-Lun Huang et al.   OPHTHALMIC RESEARCH

Global Prevalence of Glaucoma and Projections of Glaucoma Burden through 2040

(2014) Yih-Chung Tham et al.   OPHTHALMOLOGY

Caspase-8 promotes NLRP1/NLRP3 inflammasome activation and IL-1  production in acute glaucoma

(2014) W. Chi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TLR activation regulates damage-associated molecular pattern isoforms released during pyroptosis

(2012) Sanna Nyström et al.   EMBO JOURNAL

Role of Inflammasomes in Host Defense againstCitrobacter rodentiumInfection

(2012) Zhiping Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation of NLRC4 is critical for inflammasome activation

(2012) Yan Qu et al.   NATURE

Protection of Retinal Ganglion Cells and Retinal Vasculature by Lycium Barbarum Polysaccharides in a Mouse Model of Acute Ocular Hypertension

(2012) Xue-Song Mi et al.   PLoS One

The NLR Adaptor ASC/PYCARD Regulates DUSP10, Mitogen-activated Protein Kinase (MAPK), and Chemokine Induction Independent of the Inflammasome

(2011) Debra J. Taxman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inflammation-induced tumorigenesis in the colon is regulated by caspase-1 and NLRC4

(2010) B. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome

(2010) E. A. Miao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Assessing optic nerve pathology with diffusion MRI: from mouse to human

(2008) Junqian Xu et al.   NMR IN BIOMEDICINE