EGFR-targeting antitumor therapy: Neuregulins or antibodies?

MgO nanoparticles coated with polyethylene glycol as carrier for 2-Methoxyestradiol anticancer drug

(2019) Aline Alfaro et al.   PLoS One

A theranostic nanocomposite system based on iron oxide-drug nanocages for targeted magnetic field responsive chemotherapy

(2018) Mookkandi Palsamy Kesavan et al.   Nanomedicine-Nanotechnology Biology and Medicine

Magnetic Hyperthermia and Radiation Therapy: Radiobiological Principles and Current Practice †

(2018) Spiridon Spirou et al.   Nanomaterials

Recent advances and future prospects of iron oxide nanoparticles in biomedicine and diagnostics

(2018) N. V. Srikanth Vallabani et al.   3 Biotech

Recent advances and future prospects of iron oxide nanoparticles in biomedicine and diagnostics

(2018) N. V. Srikanth Vallabani et al.   3 Biotech

Nanoparticles and targeted drug delivery in cancer therapy

(2017) Behdokht Bahrami et al.   IMMUNOLOGY LETTERS

Development of an ErbB4 monoclonal antibody that blocks neuregulin-1-induced ErbB4 activation in cancer cells

(2016) Shogo Okazaki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Nanochemistry and Nanomedicine for Nanoparticle-based Diagnostics and Therapy

(2016) Guanying Chen et al.   CHEMICAL REVIEWS

The First-in-class Anti-EGFR Antibody Mixture Sym004 Overcomes Cetuximab Resistance Mediated by EGFR Extracellular Domain Mutations in Colorectal Cancer

(2016) F. J. Sanchez-Martin et al.   CLINICAL CANCER RESEARCH

Magnetite nanoparticles for cancer diagnosis, treatment, and treatment monitoring: recent advances

(2016) Richard A. Revia et al.   Materials Today

MM-151 overcomes acquired resistance to cetuximab and panitumumab in colorectal cancers harboring EGFR extracellular domain mutations

(2016) Sabrina Arena et al.   Science Translational Medicine

Functional nanoparticles for magnetic resonance imaging

(2016) Xinpei Mao et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Surface Functionalization of Nanoparticles with Polyethylene Glycol: Effects on Protein Adsorption and Cellular Uptake

(2015) Beatriz Pelaz et al.   ACS Nano

Characterizing the patterns of clonal selection in circulating tumor DNA from patients with colorectal cancer refractory to anti-EGFR treatment

(2015) M. P. Morelli et al.   ANNALS OF ONCOLOGY

Iron Oxide Based Nanoparticles for Multimodal Imaging and Magnetoresponsive Therapy

(2015) Nohyun Lee et al.   CHEMICAL REVIEWS

Emergence of Multiple EGFR Extracellular Mutations during Cetuximab Treatment in Colorectal Cancer

(2015) S. Arena et al.   CLINICAL CANCER RESEARCH

Safety and Pharmacokinetics/Pharmacodynamics of the First-in-Class Dual Action HER3/EGFR Antibody MEHD7945A in Locally Advanced or Metastatic Epithelial Tumors

(2015) D. Juric et al.   CLINICAL CANCER RESEARCH

Activated ErbB3 Translocates to the Nucleus via Clathrin-independent Endocytosis, Which Is Associated with Proliferating Cells

(2015) Raymond Reif et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antitumor Effects of MEHD7945A, a Dual-Specific Antibody against EGFR and HER3, in Combination with Radiation in Lung and Head and Neck Cancers

(2015) C. Li et al.   MOLECULAR CANCER THERAPEUTICS

ErbB polymorphisms: insights and implications for response to targeted cancer therapeutics

(2015) Moulay A. Alaoui-Jamali et al.   Frontiers in Genetics

The Soluble Heparin-Binding EGF-Like Growth Factor Stimulates EGF Receptor Trafficking to the Nucleus

(2015) Nataliia V. Korotkevych et al.   PLoS One

Antagonism of EGFR and HER3 Enhances the Response to Inhibitors of the PI3K-Akt Pathway in Triple-Negative Breast Cancer

(2014) J. J. Tao et al.   Science Signaling

PEGylated versus non-PEGylated magnetic nanoparticles as camptothecin delivery system

(2014) Paula M Castillo et al.   Beilstein Journal of Nanotechnology

Resistance to Anti-EGFR Therapy in Colorectal Cancer: From Heterogeneity to Convergent Evolution

(2014) S. Misale et al.   Cancer Discovery

Trial Watch

(2014) Erika Vacchelli et al.   OncoImmunology

Epidermal growth factor receptor targeting in cancer: A review of trends and strategies

(2013) Chetan Yewale et al.   BIOMATERIALS

Gene expression signature of human HepG2 cell line

(2013) S. Costantini et al.   GENE

The ErbB/HER family of protein-tyrosine kinases and cancer

(2013) Robert Roskoski   PHARMACOLOGICAL RESEARCH

Interaction between natural compounds and human topoisomerase I

(2012) Silvia Castelli et al.   BIOLOGICAL CHEMISTRY

Landscape of EGFR signaling network in human cancers: Biology and therapeutic response in relation to receptor subcellular locations

(2012) Woody Han et al.   CANCER LETTERS

Dual Targeting of EGFR and HER3 with MEHD7945A Overcomes Acquired Resistance to EGFR Inhibitors and Radiation

(2012) S. Huang et al.   CANCER RESEARCH

Surface functionalization of nanoparticles for nanomedicine

(2012) Rubul Mout et al.   CHEMICAL SOCIETY REVIEWS

PEG-chitosan-coated iron oxide nanoparticles with high saturated magnetization as carriers of 10-hydroxycamptothecin: Preparation, characterization and cytotoxicity studies

(2012) Jian-Bo Qu et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Challenges in design and characterization of ligand-targeted drug delivery systems

(2012) Silvia Muro   JOURNAL OF CONTROLLED RELEASE

Study of Interaction Between PEG Carrier and Three Relevant Drug Molecules: Piroxicam, Paclitaxel, and Hematoporphyrin

(2012) Yen-Chin Li et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Rational identification of an optimal antibody mixture for targeting the epidermal growth factor receptor

(2012) Klaus Koefoed et al.   mAbs

Identification of a mutation in the extracellular domain of the Epidermal Growth Factor Receptor conferring cetuximab resistance in colorectal cancer

(2012) Clara Montagut et al.   NATURE MEDICINE

Nuclear functions and subcellular trafficking mechanisms of the epidermal growth factor receptor family

(2012) Ying-Nai Wang et al.   Cell and Bioscience

Surface Engineering of Iron Oxide Nanoparticles for Targeted Cancer Therapy

(2011) Forrest M. Kievit et al.   ACCOUNTS OF CHEMICAL RESEARCH

Theranostic Magnetic Nanoparticles

(2011) Dongwon Yoo et al.   ACCOUNTS OF CHEMICAL RESEARCH

Engineered Bivalent Ligands to Bias ErbB Receptor-mediated Signaling and Phenotypes

(2011) Steven M. Jay et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Design of water-based ferrofluids as contrast agents for magnetic resonance imaging

(2011) Maria F. Casula et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Magnetite nanoparticles for medical MR imaging

(2011) Zachary R. Stephen et al.   Materials Today

PEG-templated mesoporous silica nanoparticles exclusively target cancer cells

(2011) Catia Morelli et al.   Nanoscale

Localisation of Neuregulin 1-β3 to different sub-nuclear structures alters gene expression

(2010) Ming Wang et al.   EXPERIMENTAL CELL RESEARCH

Drug release kinetics and transport mechanisms of non-degradable and degradable polymeric delivery systems

(2010) Yao Fu et al.   Expert Opinion on Drug Delivery

Solubility profiles of poly(ethylene glycol)/solvent systems. II. comparison of thermodynamic parameters from viscosity measurements

(2010) Cemile Özdemir Di̇nç et al.   JOURNAL OF APPLIED POLYMER SCIENCE

Chemical synthesis and characterization of silver-protected vasoactive intestinal peptide nanoparticles

(2009) Rafael Fernandez-Montesinos et al.   Nanomedicine

Novel and Existing Mutations in the Tyrosine Kinase Domain of the Epidermal Growth Factor Receptor are Predictors of Optimal Resectability in Malignant Peritoneal Mesothelioma

(2008) Jason M. Foster et al.   ANNALS OF SURGICAL ONCOLOGY

Neuregulins and Cancer

(2008) J. C. Montero et al.   CLINICAL CANCER RESEARCH

Trafficking of receptor tyrosine kinases to the nucleus

(2008) Graham Carpenter et al.   EXPERIMENTAL CELL RESEARCH