Melatonin derivatives combat with inflammation-related cancer by targeting the Main Culprit STAT3

Design, synthesis and bioactivity study of N-salicyloyl tryptamine derivatives as multifunctional agents for the treatment of neuroinflammation

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Searching for new agents active against Candida albicans biofilm: A series of indole derivatives, design, synthesis and biological evaluation

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The emergence of melatonin in oncology: Focus on colorectal cancer

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Melatonin modulates airway smooth muscle cell phenotype by targeting the STAT3/Akt/GSK-3β pathway in experimental asthma

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Quinolone and indole alkaloids from the fruits of Euodia rutaecarpa and their cytotoxicity against two human cancer cell lines

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The IL-6 feed-forward loop: A driver of tumorigenesis

(2014) Qing Chang et al.   SEMINARS IN IMMUNOLOGY

Optimization of Rutaecarpine as ABCA1 Up-Regulator for Treating Atherosclerosis

(2014) Yongzhen Li et al.   ACS Medicinal Chemistry Letters

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Antagonism of the Stat3-Stat3 Protein Dimer with Salicylic Acid Based Small Molecules

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A novel small-molecule disrupts Stat3 SH2 domain–phosphotyrosine interactions and Stat3-dependent tumor processes

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Tobacco Smoke Promotes Lung Tumorigenesis by Triggering IKKβ- and JNK1-Dependent Inflammation

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Dietary and Genetic Obesity Promote Liver Inflammation and Tumorigenesis by Enhancing IL-6 and TNF Expression

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Immunity, Inflammation, and Cancer

(2010) Sergei I. Grivennikov et al.   CELL

Targeting Inflammatory Pathways for Prevention and Therapy of Cancer: Short-Term Friend, Long-Term Foe

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Tolfenamic acid decreases c-Met expression through Sp proteins degradation and inhibits lung cancer cells growth and tumor formation in orthotopic mice

(2009) Jimmie Colon et al.   INVESTIGATIONAL NEW DRUGS

Tolfenamic acid enhances pancreatic cancer cell and tumor response to radiation therapy by inhibiting survivin protein expression

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(2008) Alberto Mantovani et al.   NATURE

A chemical method for fast and sensitive detection of DNA synthesis in vivo

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