Arsenic suppresses GDF1 expression via ROS-dependent downregulation of specificity protein 1

Estrogen-regulated expression of SK3 channel in rat colonic smooth muscle contraction

(2020) Wenjie Xiong et al.   LIFE SCIENCES

Association of functional variant in GDF1 promoter with risk of congenital heart disease and its regulation by Nkx2.5

(2019) Xiaobo Gao et al.   CLINICAL SCIENCE

P66Shc expression in diabetic rat retina

(2018) Ming-Hui Zhao et al.   BMC Ophthalmology

Sumoylation-deficient Prdx6 repairs aberrant Sumoylation-mediated Sp1 dysregulation-dependent Prdx6 repression and cell injury in aging and oxidative stress

(2018) Bhavana Chhunchha et al.   Aging-US

Probucol ameliorates renal injury in diabetic nephropathy by inhibiting the expression of the redox enzyme p66Shc

(2017) Shikun Yang et al.   Redox Biology

Specificity protein 1-modulated superoxide dismutase 2 enhances temozolomide resistance in glioblastoma, which is independent of O 6 -methylguanine-DNA methyltransferase

(2017) Kwang-Yu Chang et al.   Redox Biology

Benzyl Isothiocyanate (BITC) Induces Reactive Oxygen Species-dependent Repression of STAT3 Protein by Down-regulation of Specificity Proteins in Pancreatic Cancer

(2016) Ravi Kasiappan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SIRT1 deacetylates and stabilizes hypoxia-inducible factor-1α (HIF-1α) via direct interactions during hypoxia

(2015) Hyun-Yoo Joo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Sp1 transcription factor: A long-standing target in cancer chemotherapy

(2015) Carolina Vizcaíno et al.   PHARMACOLOGY & THERAPEUTICS

Folic acid protects against arsenic-mediated embryo toxicity by up-regulating the expression of Dvr1

(2015) Yan Ma et al.   Scientific Reports

Setdb2 controls convergence and extension movements during zebrafish gastrulation by transcriptional regulation of dvr1

(2014) Ting-Ting Du et al.   DEVELOPMENTAL BIOLOGY

Arsenic in drinking water and congenital heart anomalies in Hungary

(2014) Tamás Rudnai et al.   INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH

Mechanism of Action of Phenethylisothiocyanate and Other Reactive Oxygen Species-Inducing Anticancer Agents

(2014) I. Jutooru et al.   MOLECULAR AND CELLULAR BIOLOGY

The transcription factor Pitx2 positions the embryonic axis and regulates twinning

(2014) Angela Torlopp et al.   eLife

PIASy mediates hypoxia-induced SIRT1 transcriptional repression and epithelial-to-mesenchymal transition in ovarian cancer cells

(2013) L. Sun et al.   JOURNAL OF CELL SCIENCE

TNFα Signals via p66Shc to Induce E-Selectin, Promote Leukocyte Transmigration and Enhance Permeability in Human Endothelial Cells

(2013) Luigi Laviola et al.   PLoS One

Knockdown of p66Shc by siRNA injection rescues arsenite-induced developmental retardation in mouse preimplantation embryos

(2013) Kai Ren et al.   REPRODUCTIVE TOXICOLOGY

Salvianolic acid A preconditioning confers protection against concanavalin A-induced liver injury through SIRT1-mediated repression of p66shc in mice

(2013) Xiaomei Xu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Folate and fetal programming: a play in epigenomics?

(2013) Jean-Louis Guéant et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Nutrigenetics and Modulation of Oxidative Stress

(2012) Laura A. Da Costa et al.   ANNALS OF NUTRITION AND METABOLISM

Acetylated Sp1 inhibits PTEN expression through binding to PTEN core promoter and recruitment of HDAC1 and promotes cancer cell migration and invasion

(2012) X.-X. Kou et al.   CARCINOGENESIS

Arsenic impairs embryo development via down-regulating Dvr1 expression in zebrafish

(2012) Xiaoqiao Li et al.   TOXICOLOGY LETTERS

Repression of P66Shc Expression by SIRT1 Contributes to the Prevention of Hyperglycemia-Induced Endothelial Dysfunction

(2011) Shuang Zhou et al.   CIRCULATION RESEARCH

Concerted functions of HDAC1 and microRNA-574-5p repress alternatively splicedceramide synthase 1expression in human cancer cells

(2011) Marisa Meyers-Needham et al.   EMBO Molecular Medicine

Fetal alcohol syndrome: cardiac birth defects in mice and prevention with folate

(2010) Maria Serrano et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

PPARβ/δ regulates the human SIRT1 gene transcription via Sp1

(2010) Mizuho Okazaki et al.   ENDOCRINE JOURNAL

Arsenic trioxide downregulates specificity protein (Sp) transcription factors and inhibits bladder cancer cell and tumor growth

(2010) Indira Jutooru et al.   EXPERIMENTAL CELL RESEARCH

GT-094, a NO-NSAID, Inhibits Colon Cancer Cell Growth by Activation of a Reactive Oxygen Species-MicroRNA-27a: ZBTB10-Specificity Protein Pathway

(2010) S. S. Pathi et al.   MOLECULAR CANCER RESEARCH

Protective effect of periconceptional folic acid supplements on the risk of congenital heart defects: a registry-based case-control study in the northern Netherlands

(2009) I. M. van Beynum et al.   EUROPEAN HEART JOURNAL

Intracellular redox imbalance and extracellular amino acid metabolic abnormality contribute to arsenic-induced developmental retardation in mouse preimplantation embryos

(2009) Chuanling Zhang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Developmental mechanisms of arsenite toxicity in zebrafish (Danio rerio) embryos

(2008) Dan Li et al.   AQUATIC TOXICOLOGY