Carbamazepine at environmentally relevant concentrations caused DNA damage and apoptosis in the liver of Chinese rare minnows (Gobiocypris rarus) by the Ras/Raf/ERK/p53 signaling pathway

Organophosphate flame retardants (OPFRs) induce genotoxicity in vivo: A survey on apoptosis, DNA methylation, DNA oxidative damage, liver metabolites, and transcriptomics

(2019) Rui Chen et al.   ENVIRONMENT INTERNATIONAL

Genotoxicity assessment of antiepileptic drugs (AEDs) in human embryonic stem cells

(2019) Masumeh Kardoost et al.   EPILEPSY RESEARCH

Environmentally Relevant Concentrations of Carbamazepine Caused Endocrine-Disrupting Effects on Nontarget Organisms, Chinese Rare Minnows (Gobiocypris rarus)

(2018) Saihong Yan et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Carbamazepine as a Possible Anthropogenic Marker in Water: Occurrences, Toxicological Effects, Regulations and Removal by Wastewater Treatment Technologies

(2018) Faisal Hai et al.   Water

Environmentally relevant concentrations of carbamazepine induce liver histopathological changes and a gender-specific response in hepatic proteome of Chinese rare minnows (Gobiocypris rarus)

(2018) Saihong Yan et al.   ENVIRONMENTAL POLLUTION

Oridonin-induced mitochondria-dependent apoptosis in esophageal cancer cells by inhibiting PI3K/AKT/mTOR and Ras/Raf pathways

(2018) Jin-Huan Jiang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The first-line antiepileptic drug carbamazepine: Reaction with biologically relevant free radicals

(2018) Inês L. Martins et al.   FREE RADICAL BIOLOGY AND MEDICINE

Short-term exposure to carbamazepine causes oxidative stress on common carp (Cyprinus carpio)

(2018) Eloy Gasca-Pérez et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Effects of low concentrations of psychiatric drugs (carbamazepine and fluoxetine) on the freshwater planarian, Schmidtea mediterranea

(2018) Pearl U. Ofoegbu et al.   CHEMOSPHERE

Investigation of 8-OHdG, CYP1A, HSP70 and transcriptional analyses of antioxidant defence system in liver tissues of rainbow trout exposed to eprinomectin

(2017) Gonca Alak et al.   FISH & SHELLFISH IMMUNOLOGY

Comparison of the toxicological impacts of carbamazepine and a mixture of its photodegradation products in Scrobicularia plana

(2017) Ângela Almeida et al.   JOURNAL OF HAZARDOUS MATERIALS

Effects of the pharmaceutical contaminants ibuprofen, diclofenac, and carbamazepine alone, and in combination, on oxidative stress parameters in early life stages of tench (Tinca tinca)

(2017) V. Stancova et al.   VETERINARNI MEDICINA

Tributylphosphate (TBP) and tris (2-butoxyethyl) phosphate (TBEP) induced apoptosis and cell cycle arrest in HepG2 cells

(2017) Guofa Ren et al.   Toxicology Research

Negative feedback regulation of the ERK1/2 MAPK pathway

(2016) David Lake et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Long-term exposure to caffeine and carbamazepine: Impacts on the regenerative capacity of the polychaete Diopatra neapolitana

(2016) Adília Pires et al.   CHEMOSPHERE

Bioaccumulation, oxidative stress and genotoxicity in fish (Channa punctatus) exposed to a thermal power plant effluent

(2016) Mehjbeen Javed et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

In Silico Identification of Bioremediation Potential: Carbamazepine and Other Recalcitrant Personal Care Products

(2016) Kelly G. Aukema et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Benzo[a]pyrene induced p53-mediated cell cycle arrest, DNA repair, and apoptosis pathways in Chinese rare minnow (Gobiocypris rarus )

(2016) Lilai Yuan et al.   ENVIRONMENTAL TOXICOLOGY

Biocatalytic degradation of carbamazepine with immobilized laccase-mediator membrane hybrid reactor

(2016) Chao Ji et al.   JOURNAL OF MEMBRANE SCIENCE

Bioaccumulation and analytics of pharmaceutical residues in the environment: A review

(2016) Alan Puckowski et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Effects of carbamazepine on cortisol levels and behavioral responses to stress in the fish Jenynsia multidentata

(2016) Emilia Calcagno et al.   PHYSIOLOGY & BEHAVIOR

The impacts of pharmaceutical drugs under ocean acidification: New data on single and combined long-term effects of carbamazepine on Scrobicularia plana

(2016) Rosa Freitas et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Oxidative Stress and DNA Damage Induced by Imidacloprid in Zebrafish (Danio rerio)

(2015) Weili Ge et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Pharmaceuticals in the environment: Biodegradation and effects on natural microbial communities. A review

(2015) Anna Barra Caracciolo et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Ras and autophagy in cancer development and therapy.

(2015) Eran Schmukler et al.   Oncotarget

Effects of the human antiepileptic drug carbamazepine on the behavior, biomarkers, and heat shock proteins in the Asian clam Corbicula fluminea

(2014) Huihui Chen et al.   AQUATIC TOXICOLOGY

Loss of p53 induces cell proliferation via Ras-independent activation of the Raf/Mek/Erk signaling pathway

(2014) Matthias Drosten et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biodegradation of tributyl phosphate using Klebsiella pneumoniae sp. S3

(2013) S. V. Kulkarni et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Short-term effects of neuroactive pharmaceutical drugs on a fish species: Biochemical and behavioural effects

(2013) F.P. Brandão et al.   AQUATIC TOXICOLOGY

DNA damage and oxidative stress modulatory effects of glyphosate-based herbicide in freshwater fish, Channa punctatus

(2013) C.D. Nwani et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Disseminated neoplasia causes changes in ploidy and apoptosis frequency in cockles Cerastoderma edule

(2013) S. Díaz et al.   JOURNAL OF INVERTEBRATE PATHOLOGY

Associations of neonatal lead, cadmium, chromium and nickel co-exposure with DNA oxidative damage in an electronic waste recycling town

(2013) Wenqing Ni et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Tetramethylpyrazine induces G0/G1 cell cycle arrest and stimulates mitochondrial-mediated and caspase-dependent apoptosis through modulating ERK/p53 signaling in hepatic stellate cells in vitro

(2012) Feng Zhang et al.   APOPTOSIS

Immunoassays as high-throughput tools: Monitoring spatial and temporal variations of carbamazepine, caffeine and cetirizine in surface and wastewaters

(2012) Arnold Bahlmann et al.   CHEMOSPHERE

ATM mediates interdependent activation of p53 and ERK through formation of a ternary complex with p-p53 and p-ERK in response to DNA damage

(2012) Jee-In Heo et al.   MOLECULAR BIOLOGY REPORTS

FLIPLinduces caspase 8 activity in the absence of interdomain caspase 8 cleavage and alters substrate specificity

(2011) Cristina Pop et al.   BIOCHEMICAL JOURNAL

Carbamazepine inhibits distinct chemoconvulsant-induced seizure-like activity in Dugesia tigrina

(2011) Latha Ramakrishnan et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Effect of human pharmaceutical Carbamazepine on the quality parameters and oxidative stress in common carp (Cyprinus carpio L.) spermatozoa

(2010) Zhi-Hua Li et al.   CHEMOSPHERE

Acute toxicity of carbamazepine to juvenile rainbow trout (Oncorhynchus mykiss): Effects on antioxidant responses, hematological parameters and hepatic EROD

(2010) Zhi-Hua Li et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

ERK mediates anti-apoptotic effect through phosphorylation and cytoplasmic localization of p21Waf1/Cip1/Sdi in response to DNA damage in normal human embryonic fibroblast (HEF) cells

(2010) Jee-In Heo et al.   MOLECULAR BIOLOGY REPORTS

Evaluation of chromosome aberrations, sister chromatid exchange and micronuclei in cultured cord-blood lymphocytes of newborns of women treated for epilepsy during pregnancy

(2010) Monika Witczak et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

ERKs/p53 signal transduction pathway is involved in doxorubicin-induced apoptosis in H9c2 cells and cardiomyocytes

(2008) Jiahao Liu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Carbamazepine and diclofenac: Removal in wastewater treatment plants and occurrence in water bodies

(2008) Yongjun Zhang et al.   CHEMOSPHERE

EU-wide survey of polar organic persistent pollutants in European river waters

(2008) Robert Loos et al.   ENVIRONMENTAL POLLUTION