Article
Biochemistry & Molecular Biology
Galina N. Chelomina, Sergey P. Kukla, Viktor P. Chelomin, Pham N. Doanh
Summary: Parasite infection can lead to DNA damage, potentially involving oxidative stress and cancer development; these research findings are important for understanding the pathogenesis mechanisms of parasitic diseases.
Article
Environmental Sciences
Mariana Martinez-Perez, Francisco Arenas-Huertero, Josefina Cortes-Eslava, Ofelia Morton-Bermea, Sandra Gomez-Arroyo
Summary: The study evaluated the toxic effects of heavy metals on the plant Robinsonecio gerberifolius exposed in different sites in Mexico City, showing an increase in genotoxicity and induction of oxidative stress. The presence of toxic HM in the atmosphere of Mexico City and its metropolitan area was confirmed through the analysis of alpha- and ss-carotenoids and miR398 levels in the exposed plants.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Environmental Sciences
Sabrine Hattab, Iteb Boughattas, Tiziana Cappello, Nesrine Zitouni, Ghada Touil, Ilef Romdhani, Alexandre Livet, Nourreddine Bousserrhine, Mohamed Banni
Summary: Heavy metal pollution has harmful consequences on soil fertility, and earthworms are used as test organisms to evaluate the ecotoxicity of polluted soils. This study exposed Eisenia andrei to polymetallic contaminated soils for 7 and 14 days in southeastern Tunisia. The results showed increased heavy metal accumulation, genotoxicity, and cytotoxicity in earthworms after 14 days of exposure, as well as changes in biochemical and transcriptional responses. These findings support the use of earthworms as bioindicator species for pollution monitoring and provide valuable information about the harmful impact of biota exposure to contaminated soils.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Pharmacology & Pharmacy
Hossam El Din H. Abdelhafez, Amr A. Abdallah, Asmaa A. El-Dahshan, Yasser A. Abd El-Baset, Osama M. Morsy, Mohamed Bedair M. Ahmed
Summary: The study found that fipronil induces various health risks in vivo, while date extract can alleviate the toxic effects of fipronil but failed to reduce genotoxicity.
Article
Environmental Sciences
Nojood Altwaijry, Mohd Shahnawaz Khan, Gouse M. Shaik, Mohammad Tarique, Mehjbeen Javed
Summary: In this study, various parameters of oxidative stress, immune response, and abnormalities in the erythrocyte nucleus of Labeo rohita inhabiting the polluted Kshipra River, India, were measured. The heavy metal concentrations in the river water were in the order of Ni > Fe > Cd > Cr > Mn > Zn > Cu. The fish showed increased levels of antioxidant enzymes in gills, liver, and gut compared to the reference fish, but decreased levels of GST and GSH. Heavy metals also caused immunosuppression and histopathological changes in the fish. These findings highlight the potential impact of heavy metal-induced stress on fish inhabiting polluted river water and the importance of pollution control.
ARCHIVES OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Zhangjian Chen, Jiaqi Shi, Yi Zhang, Shuo Han, Jiahe Zhang, Guang Jia
Summary: The genotoxic effects and underlying mechanisms of titanium dioxide nanoparticles (TiO2 NPs) on human bronchial epithelial cells (BEAS-2B) were investigated in this study. TiO2 NPs were found to induce cytotoxicity, oxidative stress, and DNA oxidative damage, with DNA oxidative damage being a more sensitive indicator for detecting the genotoxicity of TiO2 NPs.
Article
Environmental Sciences
Komal Sharma, Priya Saxena, Alka Kumari
Summary: Chromium occurs in different oxidation states, with hexavalent forms being more toxic and primarily resulting from human activities. A hydroponic experiment was conducted to compare the remediation abilities of Marsilea minuta and Pistia stratiotes towards chromium. Both plants accumulated the highest amounts of chromium at a concentration of 1.5 mM. Increasing concentrations of chromium led to decreased plant dry weights and increased levels of malondialdehyde (MDA). The results suggest that both macrophytes are suitable for chromium phytoremediation, and the antioxidant enzyme activity is vital for understanding plant physiology under metal stress.
BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Kantha DeiviArunachalam, Jaya Krishna Kuruva, Kumara Perumal Pradhoshini, Mohamed Saiyad Musthafa, Caterina Faggio
Summary: The study demonstrated that the methanolic leaf extract of Morinda tinctoria has a protective effect against cadmium toxicity in fish by enhancing antioxidant and antigenotoxic status, reducing oxidative stress and genotoxic effects.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2021)
Article
Environmental Sciences
Wenjie Zhang, Xiaoming Xia, Jinhua Wang, Lusheng Zhu, Jun Wang, Guangchi Wang, Yangyang Chen, Young Mo Kim
Summary: The study utilized artificial soil poisoning method to investigate the antioxidative stress mechanism and gene changes of earthworms (Eisenia foetida) after exposure to nitenpyram. The toxic effects were analyzed comprehensively using the IBRv2 method, showing significant impact on the physiological and genetic levels of earthworms.
Article
Environmental Sciences
Chunmei Ran, Chunguang Liu, Chu Peng, Xinxin Li, Yu Liu, Ye Li, Wenjun Zhang, Hongming Cai, Lei Wang
Summary: The oxidative stress on terrestrial animals caused by heavy metal-contaminated soil was evaluated using oxidative potential (OP), which was found to be influenced mostly by water extractable Cu, Pb, Zn, and Cd in the soil. The study also showed that oxidative stress in earthworms can be reflected through biomarkers and is negatively correlated with the OP of soils. Metabolomic analysis further confirmed the correlation between four ROS-related metabolites in earthworms and OP values, suggesting that OP can serve as an indicator for ecological risk assessment of heavy metal-contaminated soil.
ENVIRONMENTAL POLLUTION
(2023)
Article
Plant Sciences
Fatemeh Soltani, Omid Fakharzadeh Moghadam, Niloofar Nadalizadeh, Seyed Ahmad Emami, Behjat Javadi
Summary: The study demonstrated that different fractions of Absinth Tablet (AT) do not exhibit cytotoxic effects in HepG2 cells, show hepatoprotective activities, and exhibit antigenotoxic activity against H2O2-induced DNA damage. The results suggest that AT may be useful in preventing and treating oxidative stress-induced hepatic problems.
SOUTH AFRICAN JOURNAL OF BOTANY
(2021)
Article
Environmental Sciences
Laura Passatore, Fabrizio Pietrini, Serena Carloni, Lorenzo Massimi, Chiara Giusto, Massimo Zacchini, Valentina Iannilli
Summary: This study investigated the toxicity effects of bismuth (Bi) on garden cress plants. The results showed that low concentrations of Bi had no significant effects, but higher concentrations caused toxicity in terms of germination index and root length reduction. Bi exposure also induced genotoxicity and metal accumulation in the plants.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Biochemistry & Molecular Biology
Dessislava Staneva, Neli Dimitrova, Borislav Popov, Albena Alexandrova, Milena Georgieva, George Miloshev
Summary: This study investigates the early response of cancer cells to gamma radiation and oxidative stress, and explores the protective mechanisms offered by natural extracts from the resurrection plant Haberlea rhodopensis. The findings suggest that these extracts can effectively modulate the cellular response to genotoxic and oxidative stress, reducing their severity.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Multidisciplinary Sciences
Arnaud Fondjo Kouam, Micheline Masso, Ferdinand Elombo Kouoh, Rodrigue Fifen, Ibrahim Njingou, Angele Nkouatchoua Tchana, Frederic Nico Njayou, Paul Fewou Moundipa
Summary: The extract of Khaya grandifoliola has a protective effect on hepato-renal injuries induced by heavy metals, reducing oxidative stress and metal bioaccumulation.
Article
Environmental Sciences
Andrea C. Crupkin, Ariana B. Fulvi, Fernando G. Iturburu, Sandra Medici, Julieta Mendieta, Ana M. Panzeri, Mirta L. Menone
Summary: Azoxystrobin is a widely used systemic fungicide that inhibits mitochondrial respiration in target fungi, but its effects on non-target organisms are not well studied. This research evaluated biomarkers of oxidative stress, hematological, physiological, and genotoxicity in cichlid fish exposed to environmentally relevant concentrations of AZX, showing negative effects at realistic concentrations and highlighting the importance of considering developmental stage on biomarker evaluation.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
