A Developmental Toxicology Assay Platform for Screening Teratogenic Liability of Pharmaceutical Compounds

New Zealand white rabbit progeny exposed in utero to methanol are resistant to skeletal anomalies reported for rodents, but exhibit a novel vertebral defect

(2015) J. Nicole Sweeting et al.   REPRODUCTIVE TOXICOLOGY

Optimization and Performance Assessment of the Chorion-Off [Dechorinated] Zebrafish Developmental Toxicity Assay

(2015) Julieta M. Panzica-Kelly et al.   TOXICOLOGICAL SCIENCES

Exposure-Based Validation List for Developmental Toxicity Screening Assays

(2014) George P. Daston et al.   BIRTH DEFECTS RESEARCH PART B-DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY

Fishing for Teratogens: A Consortium Effort for a Harmonized Zebrafish Developmental Toxicology Assay

(2014) Jonathan S. Ball et al.   TOXICOLOGICAL SCIENCES

An integrated approach for detecting embryotoxicity and developmental toxicity of environmental contaminants using in vitro alternative methods

(2014) Miguel A. Sogorb et al.   TOXICOLOGY LETTERS

Development of a Streamlined Rat Whole Embryo Culture Assay for Classifying Teratogenic Potential of Pharmaceutical Compounds

(2012) Cindy Zhang et al.   TOXICOLOGICAL SCIENCES

Establishment of a Molecular Embryonic Stem Cell Developmental Toxicity Assay

(2012) Julieta M. Panzica-Kelly et al.   TOXICOLOGICAL SCIENCES

Mouse embryonic stem cell adherent cell differentiation and cytotoxicity (ACDC) assay

(2011) Marianne Barrier et al.   REPRODUCTIVE TOXICOLOGY

Inter-laboratory assessment of a harmonized zebrafish developmental toxicology assay – Progress report on phase I

(2011) A.-L. Gustafson et al.   REPRODUCTIVE TOXICOLOGY

Evaluation of Novel High-Throughput Embryonic Stem Cell Tests with New Molecular Markers for Screening Embryotoxic Chemicals In Vitro

(2011) Noriyuki Suzuki et al.   TOXICOLOGICAL SCIENCES

A dysmorphology score system for assessing embryo abnormalities in rat whole embryo culture

(2010) Cindy X. Zhang et al.   BIRTH DEFECTS RESEARCH PART B-DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY

Morphological score assignment guidelines for the dechorionated zebrafish teratogenicity assay

(2010) Julieta M. Panzica-Kelly et al.   BIRTH DEFECTS RESEARCH PART B-DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY

Development of a zebrafish embryo teratogenicity assay and quantitative prediction model

(2010) Kimberly C. Brannen et al.   BIRTH DEFECTS RESEARCH PART B-DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY

In vitro developmental toxicology assays: A review of the state of the science of rodent and zebrafish whole embryo culture and embryonic stem cell assays

(2010) Karen Augustine-Rauch et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

Evaluation of Developmental Toxicant Identification Using Gene Expression Profiling in Embryonic Stem Cell Differentiation Cultures

(2010) Dorien A. M. van Dartel et al.   TOXICOLOGICAL SCIENCES

Monitoring Developmental Toxicity in the Embryonic Stem Cell Test Using Differential Gene Expression of Differentiation-Related Genes

(2010) Dorien A. M. van Dartel et al.   TOXICOLOGICAL SCIENCES

Chemical regulators have overreached

(2009) Thomas Hartung et al.   NATURE

Early gene expression changes during embryonic stem cell differentiation into cardiomyocytes and their modulation by monobutyl phthalate

(2009) Dorien A.M. van Dartel et al.   REPRODUCTIVE TOXICOLOGY

Embryonic Stem Cell Test Remastered: Comparison between the Validated EST and the New Molecular FACS-EST for Assessing Developmental Toxicity In Vitro

(2009) Roland Buesen et al.   TOXICOLOGICAL SCIENCES

Transcriptomics-based identification of developmental toxicants through their interference with cardiomyocyte differentiation of embryonic stem cells

(2009) Dorien A.M. van Dartel et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

State of the art in developmental toxicity screening methods and a way forward: a meeting report addressing embryonic stem cells, whole embryo culture, and zebrafish

(2008) Robert Chapin et al.   BIRTH DEFECTS RESEARCH PART B-DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY

Predictive Teratology: Teratogenic Risk-Hazard Identification Partnered in the Discovery Process

(2008) K. Augustine-Rauch   CURRENT DRUG METABOLISM

PPARγ and Early Human Placental Development

(2008) Thierry Fournier et al.   CURRENT MEDICINAL CHEMISTRY

Review of the expression of peroxisome proliferator-activated receptors alpha (PPARα), beta (PPARβ), and gamma (PPARγ) in rodent and human development

(2008) Barbara D. Abbott   REPRODUCTIVE TOXICOLOGY

Fetal and Neonatal Effects of Maternal Drug Treatment for Depression

(2008) Jaques Belik   SEMINARS IN PERINATOLOGY

Development of a New Screening Assay to Identify Proteratogenic Substances using Zebrafish Danio rerio Embryo Combined with an Exogenous Mammalian Metabolic Activation System (mDarT)

(2008) François Busquet et al.   TOXICOLOGICAL SCIENCES