Discovery of novel indole‐1,2,4‐triazole derivatives as tubulin polymerization inhibitors

Molecular Dynamics Analysis of Binding Sites of Epidermal Growth Factor Receptor Kinase Inhibitors

(2020) Dong-Dong Li et al.   ACS Omega

Molecular insights into catalytic specificity of α-L-rhamnosidase from Bacteroides thetaiotaomicron by molecular docking and dynamics

(2020) Dong-Dong Li et al.   CHEMICAL PHYSICS LETTERS

Synthesis, and biological evaluation of 3,6-diaryl-[1,2,4]triazolo[4,3-a]pyridine analogues as new potent tubulin polymerization inhibitors

(2020) Fang Yang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Novel [1,2,4]triazolo[1,5-a]pyrimidine derivatives as potent antitubulin agents: Design, multicomponent synthesis and antiproliferative activities

(2019) Fang Yang et al.   BIOORGANIC CHEMISTRY

Discovery of a potent microtubule-targeting agent: Synthesis and biological evaluation of water-soluble amino acid prodrug of combretastatin A-4 derivatives

(2015) Kun Yu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Design and Synthesis of Aminostilbene-Arylpropenones as Tubulin Polymerization Inhibitors

(2014) Ahmed Kamal et al.   ChemMedChem

Synthesis and biological evaluations of new analogs of 2-methoxyestradiol: Inhibitors of tubulin and angiogenesis

(2014) Eirik Johansson Solum et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, Synthesis, and Biological Evaluation of Novel Pyridine-Bridged Analogues of Combretastatin-A4 as Anticancer Agents

(2014) Shilong Zheng et al.   JOURNAL OF MEDICINAL CHEMISTRY

The Novel Microtubule-Destabilizing Drug BAL27862 Binds to the Colchicine Site of Tubulin with Distinct Effects on Microtubule Organization

(2014) Andrea E. Prota et al.   JOURNAL OF MOLECULAR BIOLOGY

Synthesis of imidazo[2,1-b][1,3,4]thiadiazole–chalcones as apoptosis inducing anticancer agents

(2014) Ahmed Kamal et al.   MedChemComm

The Somatic Genomic Landscape of Glioblastoma

(2013) Cameron W. Brennan et al.   CELL

The epidermal growth factor receptor variant III (EGFRvIII): where wild things are altered

(2013) Hui K. Gan et al.   FEBS Journal

cis-Restricted 3-Aminopyrazole Analogues of Combretastatins: Synthesis from Plant Polyalkoxybenzenes and Biological Evaluation in the Cytotoxicity and Phenotypic Sea Urchin Embryo Assays

(2013) Dmitry V. Tsyganov et al.   JOURNAL OF NATURAL PRODUCTS

Phase II trial of combretastatin A4 phosphate, carboplatin, and paclitaxel in patients with platinum-resistant ovarian cancer

(2011) M. Zweifel et al.   ANNALS OF ONCOLOGY

Discovery of vinylogous carbamates as a novel class of β-ketoacyl-acyl carrier protein synthase III (FabH) inhibitors

(2011) Huan-Qiu Li et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Design, synthesis and biological evaluation of urea derivatives from o-hydroxybenzylamines and phenylisocyanate as potential FabH inhibitors

(2011) Zi-Lin Li et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Antitumor Agents. 284. New Desmosdumotin B Analogues with Bicyclic B-Ring as Cytotoxic and Antitubulin Agents

(2011) Kyoko Nakagawa-Goto et al.   JOURNAL OF MEDICINAL CHEMISTRY

Discovery of 7-Hydroxy-6-methoxy-2-methyl-3-(3,4,5-trimethoxybenzoyl)benzo[b]furan (BNC105), a Tubulin Polymerization Inhibitor with Potent Antiproliferative and Tumor Vascular Disrupting Properties

(2011) Bernard L. Flynn et al.   JOURNAL OF MEDICINAL CHEMISTRY

Characterization of the Colchicine Binding Site on Avian Tubulin Isotype βVI

(2010) Shubhada Sharma et al.   BIOCHEMISTRY

A Phase Ib trial of CA4P (combretastatin A-4 phosphate), carboplatin and paclitaxel in patients with advanced cancer

(2010) G J Rustin et al.   BRITISH JOURNAL OF CANCER

Microtubule-binding agents: a dynamic field of cancer therapeutics

(2010) Charles Dumontet et al.   NATURE REVIEWS DRUG DISCOVERY

Microtubule dynamics as a target in oncology

(2008) April L. Risinger et al.   CANCER TREATMENT REVIEWS

Newer Cytotoxic Agents: Attacking Cancer Broadly

(2008) B. A. Teicher   CLINICAL CANCER RESEARCH