Behavior and lineage progression of neural progenitors in the mammalian cortex

Cell stress in cortical organoids impairs molecular subtype specification

(2020) Aparna Bhaduri et al.   NATURE

Cell type composition and circuit organization of clonally related excitatory neurons in the juvenile mouse neocortex

(2020) Cathryn R Cadwell et al.   eLife

Centrosome anchoring regulates progenitor properties and cortical formation

(2020) Wei Shao et al.   NATURE

Astrocyte layers in the mammalian cerebral cortex revealed by a single-cell in situ transcriptomic map

(2020) Omer Ali Bayraktar et al.   NATURE NEUROSCIENCE

Cortical Neural Stem Cell Lineage Progression Is Regulated by Extrinsic Signaling Molecule Sonic Hedgehog

(2020) Yue Zhang et al.   Cell Reports

Transcriptome analysis and functional characterization of cerebral organoids in bipolar disorder

(2020) Annie Kathuria et al.   Genome Medicine

Modeling and Targeting Alzheimer’s Disease With Organoids

(2020) Angelos Papaspyropoulos et al.   Frontiers in Pharmacology

Origins and Proliferative States of Human Oligodendrocyte Precursor Cells

(2020) Wei Huang et al.   CELL

Deconstructing cortical folding: genetic, cellular and mechanical determinants

(2019) Cristina Llinares-Benadero et al.   NATURE REVIEWS NEUROSCIENCE

Single-cell transcriptomic analysis of mouse neocortical development

(2019) Lipin Loo et al.   Nature Communications

Single-Cell Analysis of Regional Differences in Adult V-SVZ Neural Stem Cell Lineages

(2019) Dogukan Mizrak et al.   Cell Reports

Adult Neural Stem Cells and Multiciliated Ependymal Cells Share a Common Lineage Regulated by the Geminin Family Members

(2019) Gonzalo Ortiz-Álvarez et al.   NEURON

Intermediate progenitors and Tbr2 in cortical development

(2019) Robert F. Hevner   JOURNAL OF ANATOMY

Neocortical Expansion Due to Increased Proliferation of Basal Progenitors Is Linked to Changes in Their Morphology

(2019) Nereo Kalebic et al.   Cell Stem Cell

Temporal patterning of apical progenitors and their daughter neurons in the developing neocortex

(2019) L. Telley et al.   SCIENCE

Principles of progenitor temporal patterning in the developing invertebrate and vertebrate nervous system

(2019) Polina Oberst et al.   CURRENT OPINION IN NEUROBIOLOGY

Shared and derived features of cellular diversity in the human cerebral cortex

(2019) Daniel J Miller et al.   CURRENT OPINION IN NEUROBIOLOGY

Individual brain organoids reproducibly form cell diversity of the human cerebral cortex

(2019) Silvia Velasco et al.   NATURE

Temporal plasticity of apical progenitors in the developing mouse neocortex

(2019) Polina Oberst et al.   NATURE

Modeling the Evolution of Human Brain Development Using Organoids

(2019) Sydney Keaton Muchnik et al.   CELL

TBR2 coordinates neurogenesis expansion and precise microcircuit organization via Protocadherin 19 in the mammalian cortex

(2019) Xiaohui Lv et al.   Nature Communications

Cortical astrocytes develop in a plastic manner at both clonal and cellular levels

(2019) Solène Clavreul et al.   Nature Communications

A stochastic framework of neurogenesis underlies the assembly of neocortical cytoarchitecture

(2019) Alfredo Llorca et al.   eLife

Evolution of Cortical Neurogenesis in Amniotes Controlled by Robo Signaling Levels

(2018) Adrián Cárdenas et al.   CELL

Human-Specific NOTCH2NL Genes Expand Cortical Neurogenesis through Delta/Notch Regulation

(2018) Ikuo K. Suzuki et al.   CELL

Human-Specific NOTCH2NL Genes Affect Notch Signaling and Cortical Neurogenesis

(2018) Ian T. Fiddes et al.   CELL

Spatial transcriptomic survey of human embryonic cerebral cortex by single-cell RNA-seq analysis

(2018) Xiaoying Fan et al.   CELL RESEARCH

Blood Development: Hematopoietic Stem Cell Dependence and Independence

(2018) Elaine Dzierzak et al.   Cell Stem Cell

Aspm knockout ferret reveals an evolutionary mechanism governing cerebral cortical size

(2018) Matthew B. Johnson et al.   NATURE

Genetically engineered cerebral organoids model brain tumor formation

(2018) Shan Bian et al.   NATURE METHODS

Generation of human brain region–specific organoids using a miniaturized spinning bioreactor

(2018) Xuyu Qian et al.   Nature Protocols

Evolution of pallium, hippocampus, and cortical cell types revealed by single-cell transcriptomics in reptiles

(2018) Maria Antonietta Tosches et al.   SCIENCE

Layer-specific morphological and molecular differences in neocortical astrocytes and their dependence on neuronal layers

(2018) Darin Lanjakornsiripan et al.   Nature Communications

Glioblastoma Model Using Human Cerebral Organoids

(2018) Junko Ogawa et al.   Cell Reports

Clonal analysis reveals laminar fate multipotency and daughter cell apoptosis of mouse cortical intermediate progenitors

(2018) Anca B. Mihalas et al.   DEVELOPMENT

Shared and distinct transcriptomic cell types across neocortical areas

(2018) Bosiljka Tasic et al.   NATURE

Building Models of Brain Disorders with Three-Dimensional Organoids

(2018) Neal D. Amin et al.   NEURON

Homology, neocortex, and the evolution of developmental mechanisms

(2018) Steven D. Briscoe et al.   SCIENCE

Transcriptome and epigenome landscape of human cortical development modeled in organoids

(2018) Anahita Amiri et al.   SCIENCE

MeCP2-regulated miRNAs control early human neurogenesis through differential effects on ERK and AKT signaling

(2017) N Mellios et al.   MOLECULAR PSYCHIATRY

Assembly of functionally integrated human forebrain spheroids

(2017) Fikri Birey et al.   NATURE

Guided self-organization and cortical plate formation in human brain organoids

(2017) Madeline A Lancaster et al.   NATURE BIOTECHNOLOGY

The use of brain organoids to investigate neural development and disease

(2017) Elizabeth Di Lullo et al.   NATURE REVIEWS NEUROSCIENCE

Neocortical Sox9+ radial glia generate glutamatergic neurons for all layers, but lack discernible evidence of early laminar fate restriction

(2017) E. S. Kaplan et al.   Neural Development

Spatiotemporal gene expression trajectories reveal developmental hierarchies of the human cortex

(2017) Tomasz J. Nowakowski et al.   SCIENCE

An Organoid-Based Model of Cortical Development Identifies Non-Cell-Autonomous Defects in Wnt Signaling Contributing to Miller-Dieker Syndrome

(2017) Vira Iefremova et al.   Cell Reports

Brain-Region-Specific Organoids Using Mini-bioreactors for Modeling ZIKV Exposure

(2016) Xuyu Qian et al.   CELL

2D and 3D Stem Cell Models of Primate Cortical Development Identify Species-Specific Differences in Progenitor Behavior Contributing to Brain Size

(2016) Tomoki Otani et al.   Cell Stem Cell

Modeling of Autism Using Organoid Technology

(2016) Hwan Choi et al.   MOLECULAR NEUROBIOLOGY

A comprehensive transcriptional map of primate brain development

(2016) Trygve E. Bakken et al.   NATURE

Hedgehog signaling promotes basal progenitor expansion and the growth and folding of the neocortex

(2016) Lei Wang et al.   NATURE NEUROSCIENCE

Oligodendrocyte heterogeneity in the mouse juvenile and adult central nervous system

(2016) S. Marques et al.   SCIENCE

Zika virus impairs growth in human neurospheres and brain organoids

(2016) P. P. Garcez et al.   SCIENCE

Cortical Folding: When, Where, How, and Why?

(2015) Georg F. Striedter et al.   Annual Review of Neuroscience

Cux2-Positive Radial Glial Cells Generate Diverse Subtypes of Neocortical Projection Neurons and Macroglia

(2015) Matthew J. Eckler et al.   NEURON

The Outer Subventricular Zone and Primate-Specific Cortical Complexification

(2015) Colette Dehay et al.   NEURON

Cortical folding scales universally with surface area and thickness, not number of neurons

(2015) B. Mota et al.   SCIENCE

Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion

(2015) M. Florio et al.   SCIENCE

Deterministic Progenitor Behavior and Unitary Production of Neurons in the Neocortex

(2014) Peng Gao et al.   CELL

Cortical and Clonal Contribution of Tbr2 Expressing Progenitors in the Developing Mouse Brain

(2014) Navneet A. Vasistha et al.   CEREBRAL CORTEX

Neural progenitors, neurogenesis and the evolution of the neocortex

(2014) M. Florio et al.   DEVELOPMENT

Trnp1 Regulates Expansion and Folding of the Mammalian Cerebral Cortex by Control of Radial Glial Fate

(2013) Ronny Stahl et al.   CELL

Regulation of cerebral cortex size and folding by expansion of basal progenitors

(2013) Miki Nonaka-Kinoshita et al.   EMBO JOURNAL

Cerebral organoids model human brain development and microcephaly

(2013) Madeline A. Lancaster et al.   NATURE

Fezf2 Expression Identifies a Multipotent Progenitor for Neocortical Projection Neurons, Astrocytes, and Oligodendrocytes

(2013) Chao Guo et al.   NEURON

Precursor Diversity and Complexity of Lineage Relationships in the Outer Subventricular Zone of the Primate

(2013) Marion Betizeau et al.   NEURON

Self-organization of axial polarity, inside-out layer pattern, and species-specific progenitor dynamics in human ES cell-derived neocortex

(2013) T. Kadoshima et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Complex invasion pattern of the cerebral cortex bymicroglial cells during development of the mouse embryo

(2012) Nina Swinnen et al.   GLIA

The neuron family tree remodelled

(2012) Oscar Marín   NATURE

Local generation of glia is a major astrocyte source in postnatal cortex

(2012) Woo-Ping Ge et al.   NATURE

Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses

(2012) Yichen Shi et al.   NATURE NEUROSCIENCE

Fate-Restricted Neural Progenitors in the Mammalian Cerebral Cortex

(2012) S. J. Franco et al.   SCIENCE

Modelling schizophrenia using human induced pluripotent stem cells

(2011) Kristen J. Brennand et al.   NATURE

A Role for Intermediate Radial Glia in the Tangential Expansion of the Mammalian Cerebral Cortex

(2010) Isabel Reillo et al.   CEREBRAL CORTEX

Heterogeneity in Ventricular Zone Neural Precursors Contributes to Neuronal Fate Diversity in the Postnatal Neocortex

(2010) E. K. Stancik et al.   JOURNAL OF NEUROSCIENCE

Neurogenic radial glia in the outer subventricular zone of human neocortex

(2010) David V. Hansen et al.   NATURE

OSVZ progenitors of human and ferret neocortex are epithelial-like and expand by integrin signaling

(2010) Simone A Fietz et al.   NATURE NEUROSCIENCE

Intermediate Neuronal Progenitors (Basal Progenitors) Produce Pyramidal–Projection Neurons for All Layers of Cerebral Cortex

(2009) Tom Kowalczyk et al.   CEREBRAL CORTEX

Self-Organized Formation of Polarized Cortical Tissues from ESCs and Its Active Manipulation by Extrinsic Signals

(2008) Mototsugu Eiraku et al.   Cell Stem Cell

An intrinsic mechanism of corticogenesis from embryonic stem cells

(2008) Nicolas Gaspard et al.   NATURE