Review
Food Science & Technology
Behnaz Pourrajab, Elham Sharifi-Zahabi, Sepideh Soltani, Hossein Shahinfar, Farzad Shidfar
Summary: This study compared the effects of canola oil and olive oil consumption on serum lipid profiles in adults. The results showed that canola oil consumption significantly reduced LDL-c, TC, and LDL-c/HDL-c ratio levels compared to olive oil, with no significant changes in other blood lipid components. Therefore, replacing olive oil with canola oil may have cardioprotective impacts.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Article
Nutrition & Dietetics
Guohua Li, Wenlu Yu, Hexiang Yang, Xinyue Wang, Tianyou Ma, Xiaoqin Luo
Summary: This study investigated the association between serum ferritin (SF) levels and dyslipidemia in American adults, and found a significant correlation, especially in females. Furthermore, the study revealed a relationship between dietary iron intake and dyslipidemia, specifically High-TG dyslipidemia in females.
Review
Cardiac & Cardiovascular Systems
Sajjad Moradi, Hamed Mohammadi, Aftab Javaheri, Abed Ghavami, Mohammad Hossein Rouhani
Summary: In men, higher neck circumference was positively correlated with total cholesterol, low-density lipoprotein cholesterol, and triglycerides, but inversely correlated with high-density lipoprotein cholesterol. In unhealthy women, higher neck circumference was inversely associated with high-density lipoprotein cholesterol and directly related to low-density lipoprotein cholesterol.
EUROPEAN JOURNAL OF CARDIOVASCULAR NURSING
(2021)
Article
Psychiatry
Jieqiong Hu, Yunxin Ji, Xiao E. Lang, Xiang-Yang Zhang
Summary: This study aimed to investigate the prevalence of abnormal lipid metabolism and its correlates in Chinese first-episode and drug-naive MDD patients. The prevalence of abnormal lipid metabolism in these patients was found to be quite high, and the severity of psychiatric symptoms may be closely associated with the presence of abnormal lipid metabolism in MDD patients.
JOURNAL OF PSYCHIATRIC RESEARCH
(2023)
Article
Orthopedics
Si-ming Xu, Ke Lu, Xu-feng Yang, Yao-wei Ye, Min-zhe Xu, Qin Shi, Ya-qin Gong, Chong Li
Summary: This retrospective cross-sectional study investigated the association between serum 25(OH)D levels and lipid profiles in osteoporosis patients. The results showed an inverse relationship between 25(OH)D levels and blood triglyceride concentration, and a positive association with high-density lipoprotein, apolipoprotein-A, and lipoprotein A levels. Nonlinear relationships and a threshold effect were also observed between 25(OH)D levels and total cholesterol and low-density lipoprotein cholesterol. These findings provide insight for appropriate vitamin D supplementation and potential reduction in cardiovascular disease incidence in osteoporosis patients.
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
(2023)
Review
Pharmacology & Pharmacy
Parisa Rahmani, Ebru Melekoglu, Sogand Tavakoli, Nasser Malekpour Alamdari, Pejman Rohani, Mohammad Hassan Sohouli
Summary: This study evaluated the effects of Red Yeast Rice on serum lipid levels in adults, and the results showed that it significantly decreased total cholesterol, LDL cholesterol, and triglyceride concentrations, while increasing HDL cholesterol concentration.
EXPERT REVIEW OF CLINICAL PHARMACOLOGY
(2023)
Article
Clinical Neurology
Xiaohong Wang, Liying Yang, Jiacheng Liu, Chuanyi Kang, Yue Zheng, Siyu Qiu, Ying Zhao, Colin B. Goodman, Hanjing Emily Wu, Na Zhao, Xiangyang Zhang
Summary: This study found differences in depression severity, anxiety severity, and lipid levels between patients with psychotic major depressive disorder (PMD) and those with non-psychotic major depressive disorder (NPMD) in first-episode and drug-naive (FEDN) MDD patients.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Review
Cardiac & Cardiovascular Systems
Fengdie Ma, Peiqiang Li, Shasha Zhang, Wenjing Shi, Jing Wang, Qinglong Ma, Meie Zhao, Ziyan Nie, Handan Xiao, Xinyi Chen, Xiaodong Xie
Summary: Lipid levels in adult congenital heart disease patients were significantly lower than those in the control group, while hemoglobin A1c levels were higher.
BMC CARDIOVASCULAR DISORDERS
(2023)
Article
Nutrition & Dietetics
Xin Yan, Yujuan Gao, Qi Zhao, Xiaohua Qiu, Mi Tian, Jinghong Dai, Yi Zhuang
Summary: The lipid ratios, including TC-HDL-C and non-HDL-C, were found to be independent risk factors for the severity of PAP. TC/HDL-C showed promise as a biomarker for the severity of PAP.
FRONTIERS IN NUTRITION
(2021)
Review
Pharmacology & Pharmacy
Osama Alomar, Kehinde S. Okunade, Hamed Kord Varkaneh, Ghada Ghourab, Jouri Ahmed Alsourani, Kamar Allayl Alras, Mohd Diya Masmoum, Aya Alfardous Alazm, Ismail A. Al-Badawi, Hany Salem, Ahmed Abu-Zaid
Summary: This study found that anastrozole administration in humans can effectively reduce total cholesterol and high-density lipoprotein cholesterol levels, but has no impact on triglycerides and low-density lipoprotein cholesterol levels.
CLINICAL THERAPEUTICS
(2022)
Review
Nutrition & Dietetics
Agnieszka Baranska, Agata Blaszczuk, Malgorzata Polz-Dacewicz, Wieslaw Kanadys, Maria Malm, Mariola Janiszewska, Marian Jedrych
Summary: The study found that soy protein and isoflavones have significant effects in reducing total cholesterol and LDL-C concentrations, but their impact on HDL-C and triglyceride levels is not significant. However, the effects on glucose and insulin metabolism are not significant. Therefore, larger and longer studies are still needed to determine their benefits in glucose and lipid metabolism.
Review
Pharmacology & Pharmacy
Fang Yang, Nana Li, Mihnea-Alexandru Gaman, Ning Wang
Summary: The study found that raloxifene can significantly increase high-density lipoprotein cholesterol levels in women, while significantly reducing total cholesterol and low-density lipoprotein cholesterol levels. Additionally, a significant decrease in serum triglycerides levels can be observed with raloxifene treatment duration of <= 26 weeks and baseline TG concentrations of <= 130 mg/dL.
PHARMACOLOGICAL RESEARCH
(2021)
Review
Pharmacology & Pharmacy
Changyu Lv, Wencui Zhang, Xia Tan, Xianping Shang, Mihnea-Alexandru Gaman, Hany Salem, Ahmed Abu-Zaid, Xiaohong Wang
Summary: Tibolone treatment decreases total cholesterol, high-density lipoprotein cholesterol, and triglyceride levels, with a significant reduction in low-density lipoprotein cholesterol observed when administered for <= 26 weeks. The decrease in triglyceride and total cholesterol concentrations is more pronounced in patients with a BMI >= 25 kg/m(2).
PHARMACOLOGICAL RESEARCH
(2021)
Review
Obstetrics & Gynecology
Zhen Wang, Lanlan Fang, Ze Wu, Yuxi Li, Qiongqiong Jia, Jung-Chien Cheng, Ying-Pu Sun
Summary: The meta-analysis findings suggest that patients with premature ovarian insufficiency (POI) have significantly higher levels of serum total cholesterol, low-density lipoprotein cholesterol (LDL-C), and triglyceride, but no significant difference in high-density lipoprotein cholesterol (HDL-C) levels compared to controls. These results indicate that elevations in unfavorable lipids may contribute to the increased risk of cardiovascular diseases observed in patients with POI.
REPRODUCTIVE BIOMEDICINE ONLINE
(2022)
Review
Medicine, General & Internal
Fatemeh Alsadat Rahnemaei, Reza Pakzad, Azam Amirian, Iraj Pakzad, Fatemeh Abdi
Summary: This meta-analysis study on the effect of GDM on lipid profile found that GDM patients had significantly higher levels of total cholesterol, triglycerides, very low-density lipoproteins, and TG/HDL ratio compared to normal pregnant women, with lower levels of high-density lipoprotein. Elevated serum triglyceride had the strongest impact on GDM, suggesting it could be a reliable marker for diagnosis.
Review
Neurosciences
Fereshteh Dehghani, Shima Abdollahi, Farzad Shidfar, Cain C. T. Clark, Sepideh Soltani
Summary: This systematic review and meta-analysis found that probiotics supplementation may be effective in elevating brain-derived neurotrophic factor (BDNF) levels in patients with depression and neurological disorders. A mixture of Lactobacillus and Bifidobacterium genera appeared to show greater efficacy than single genus supplements. However, the low quality of evidence suggests the need for more large-scale, high-quality randomized controlled trials for reliable conclusions.
NUTRITIONAL NEUROSCIENCE
(2023)
Article
Biochemistry & Molecular Biology
Masoumeh Khalighi Sikaroudi, Meghdad Sedaghat, Farzad Shidfar, Sepide Talebi, Fatemeh Sadat Hosseini-Baharanchi, Mohsen Masoodi, Safoura Vasheghani Farahani
Summary: Oral administration of l-arginine can heal chronic anal fissures by reducing internal anal sphincter pressure and improving clinical symptoms and quality of life.
Review
Medicine, General & Internal
Yong-Feng Chen, Jing Li, Ling-Long Xu, Mihnea-Alexandru Gaman, Zhen-You Zou
Summary: As an important treatment for acute myeloid leukemia, allogeneic hematopoietic stem cell transplantation (allo-HSCT) has broadened the indications for HSCT and improved long-term survival. However, there are still high risks associated with allo-HSCT, such as hematopoietic reconstitution failure and graft-versus-host disease, which are bottlenecks for further improvements in allo-HSCT efficacy. This paper reviews the progress of relevant research regarding these aspects.
WORLD JOURNAL OF CLINICAL CASES
(2023)
Review
Biochemistry & Molecular Biology
Mihnea-Alexandru Gaman, Vincent Kipkorir, Bahadar S. Srichawla, Arkadeep Dhali, Amelia Maria Gaman, Camelia Cristina Diaconu
Summary: This study systematically reviewed the literature on the impact of primary arterial hypertension (HTN) in myeloproliferative neoplasms (MPNs). The results showed that HTN is the most common comorbidity encountered in MPNs, with effects on thrombosis occurrence and patient survival. Drug-induced HTN also poses challenges in MPNs management. Further research is needed to investigate the characteristics of MPNs patients with HTN, and the contribution of HTN to thrombotic complications, survival, and management in MPNs.
Review
Food Science & Technology
Zhao Yang, Zhuo Shao, Weiyi Ouyang, Lu Ying, Rui Guo, Mingxuan Hao, Youfeng Liang, Wenjing Zhang, Xiaoyang Chen, Ruolan Chen, Changyuan Yu, Kousalya Prabahar, Mihnea-Alexandru Gaman, Hamed Kord-Varkaneh, Hao Li, Binbin Zhao
Summary: A meta-analysis of multiple studies found that green coffee extract can reduce waist circumference, body mass index, and body weight. The results confirm the beneficial effects of green coffee extract in obesity management.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Review
Chemistry, Medicinal
Elham Sharifi-Zahabi, Fatemeh Hajizadeh-Sharafabad, Seyed Mostafa Nachvak, Soheila Mirzaian, Sahar Darbandi, Farzad Shidfar
Summary: This study aimed to assess the molecular effects of theobromine on cardiovascular risk factors through a comprehensive evaluation of in vitro and in vivo studies. The results showed that theobromine may have beneficial effects on inflammatory factors, lipid profile, and vascular function markers. However, further studies with longer duration and lower doses are needed for confirmation.
PHYTOTHERAPY RESEARCH
(2023)
Article
Food Science & Technology
Reyhaneh Darvish Damavandi, Farzad Shidfar, Mohammad Najafi, Leila Janani, Mohsen Masoodi, Javad Heshmati, Somayeh Ziaei
Summary: Non-alcoholic fatty liver disease (NAFLD) affects nearly one-quarter of the worldwide adult population and is a serious liver disease. Recent studies have shown beneficial effects of purslane intake on oxidative stress and inflammation in NAFLD patients. This randomized double-blinded clinical trial investigated the efficacy and safety of purslane intake in NAFLD patients. The results showed a significant decrease in NF-kB p65 nuclear activity in the purslane group compared to the placebo group, suggesting that purslane intake may be a useful therapy for managing hyper inflammation in NAFLD patients.
JOURNAL OF FUNCTIONAL FOODS
(2023)
Article
Medicine, General & Internal
Taraka Krishna Nulukurthi, L. V. Simhachalam Kutikuppala, Sai Kiran Kuchana, Mihnea-Alexandru Gaman, Samrat Babu Koirala, Sri Harsha Boppana
Summary: Feeding jejunostomy (FJ) is a common surgical procedure for enteral nutrition, but intussusception is a rare and challenging complication. Prompt diagnosis and surgical intervention are required. FJ can lead to potentially fatal consequences, such as infection, tube dislocation, electrolyte imbalances, and gastrointestinal symptoms. A case of intussusception caused by FJ in a patient with esophageal carcinoma was successfully managed. Fatal complications like intussusception in FJ can be prevented by paying attention to technical considerations.
CLINICAL CASE REPORTS
(2023)
Review
Oncology
Mihnea-Alexandru Gaman, Matei-Alexandru Cozma, Muhammad Romail Manan, Bahadar S. Srichawla, Arkadeep Dhali, Sajjad Ali, Ahmed Nahian, Andrew C. Elton, L. V. Simhachalam Kutikuppala, Richard Christian Suteja, Sebastian Diebel, Amelia Maria Gaman, Camelia Cristina Diaconu
Summary: Myeloproliferative neoplasms (MPNs) are clonal disorders characterized by excessive production of mature myeloid cells. Classical MPNs, such as polycythemia vera, essential thrombocythemia, and primary myelofibrosis, have a tendency to develop thrombotic complications at unusual sites. The pathogenesis of thrombotic events in MPNs is complex and involves endothelial injury, leukocyte adhesion, genetic mutations, and other factors. In this review, we discuss the epidemiology, pathogenesis, histopathology, risk factors, classification, clinical presentation, diagnosis, and management of Budd-Chiari syndrome in Philadelphia-negative MPNs.
WORLD JOURNAL OF CLINICAL ONCOLOGY
(2023)
Editorial Material
Hematology
Tarec Christoffer El-Galaly, Verena I. Gaidzik, Mihnea-Alexandru Gaman, Darko Antic, Jessica Okosun, Mhairi Copland, Veronika Sexl, Adele K. Fielding, Robin Doeswijk, Helen Parker, Martin Dreyling, Konstanze Doehner, Antonio Medina Almeida, Elizabeth Macintyre, John G. Gribben, Kirsten Gronbaek
Article
Nutrition & Dietetics
Maryam Khazdouz, Naser Ebrahimi Daryani, Makan Cheraghpour, Foroogh Alborzi, Motahareh Hasani, Shaghayegh Baradaran Ghavami, Farzad Shidfar
Summary: The purpose of this study was to investigate the therapeutic effects of selenium supplementation in ulcerative colitis patients with mild-to-moderate disease activity. The study found that taking selenomethionine capsules significantly reduced disease activity and improved quality of life.
EUROPEAN JOURNAL OF NUTRITION
(2023)
Review
Chemistry, Medicinal
Yasaman Vahedi-Mazdabadi, Hossein Shahinfar, Mohammad Toushih, Farzad Shidfar
Summary: Based on a comprehensive meta-analysis of randomized controlled trials, berberine supplementation has been shown to have a dose-dependent beneficial effect on reducing inflammatory biomarkers such as IL-6, TNF-a, and CRP in adults. However, the findings are limited by low-quality studies and significant heterogeneity, indicating that more investigation and high-quality evidence are needed to obtain comprehensive and generalizable results.
PHYTOTHERAPY RESEARCH
(2023)
Review
Chemistry, Medicinal
Ghazal Baghdadi, Farzad Shidfar, Afsaneh Dehnad
Summary: Patients undergoing maintenance dialysis have a higher incidence of cardiovascular disease compared to the general population. Pomegranate has shown potential benefits in reducing hypertension, oxidative stress, inflammation, and improving lipid profile in these patients. However, more clinical trials are needed due to limited research.
PHYTOTHERAPY RESEARCH
(2023)
Article
Nutrition & Dietetics
Fereshteh Dehghani, Mohammadreza Vafa, Ali Ebrahimkhani, Mihnea-Alexandru Gaman, Seyed Hashem Sezavar Seyedi Jandaghi
Summary: The study aimed to investigate the effects of quercetin supplementation on ICAM-1 and VCAM-1 levels, as well as depression in post-MI subjects. The results showed that 8 weeks of quercetin supplementation did not significantly affect ICAM-1 and VCAM-1 levels or depression levels.
CLINICAL NUTRITION ESPEN
(2023)
Meeting Abstract
Oncology
Mihnea-Alexandru Gaman, Bogdan Ionescu, Adina Emilia Croitoru, Ioana Mihaela Dinu, Aurelia Tatic, Alexandra Ghiaur, Delia Codruta Popa, Didona Vasilache, Daniel Coriu
CLINICAL LYMPHOMA MYELOMA & LEUKEMIA
(2023)
