NOD-like receptor signaling pathway activation: A potential mechanism underlying negative effects of benzo(α)pyrene on zebrafish

Embryo/larval toxicity and transcriptional effects in zebrafish (Danio rerio) exposed to endocrine active riverbed sediments

(2020) Luigi Viganò et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Histological, oxidative and immune changes in response to 9,10-phenanthrenequione, retene and phenanthrene in Takifugu obscurus liver

(2020) Shulun Jiang et al.   JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART A-TOXIC/HAZARDOUS SUBSTANCES & ENVIRONMENTAL ENGINEERING

Proteomics and lipidomics analyses reveal modulation of lipid metabolism by perfluoroalkyl substances in liver of Atlantic cod (Gadus morhua)

(2020) Karina Dale et al.   AQUATIC TOXICOLOGY

Contaminant accumulation and biological responses in Atlantic cod (Gadus morhua) caged at a capped waste disposal site in Kollevåg, Western Norway

(2019) Karina Dale et al.   MARINE ENVIRONMENTAL RESEARCH

Acting locally - affecting globally: RNA sequencing of gilthead sea bream with a mild Sparicotyle chrysophrii infection reveals effects on apoptosis, immune and hypoxia related genes

(2019) M. Carla Piazzon et al.   BMC GENOMICS

Adverse effects, expression of defense-related genes, and oxidative stress-induced MAPK pathway in the benzo[α]pyrene-exposed rotifer Brachionus rotundiformis

(2019) Jeonghoon Han et al.   AQUATIC TOXICOLOGY

Adverse effects of bisphenol A on Sertoli cell blood-testis barrier in rare minnow Gobiocypris rarus

(2019) Shiyu Tao et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

IL-1α and IL-1β promote NOD2-induced immune responses by enhancing MAPK signaling

(2019) Sushan Li et al.   LABORATORY INVESTIGATION

Chronic exposure to 6:2 chlorinated polyfluorinated ether sulfonate acid (F-53B) induced hepatotoxic effects in adult zebrafish and disrupted the PPAR signaling pathway in their offspring

(2019) Guohui Shi et al.   ENVIRONMENTAL POLLUTION

Metabolic disorder induces fatty liver in Japanese seabass, Lateolabrax japonicas fed a full plant protein diet and regulated by cAMP-JNK/NF-kB-caspase signal pathway

(2019) Y. Zhang et al.   FISH & SHELLFISH IMMUNOLOGY

iTRAQ-based quantitative proteomic analysis of Takifugu fasciatus liver in response to low-temperature stress

(2019) Xin Wen et al.   Journal of Proteomics

GM-CSF and CXCR4 define a T helper cell signature in multiple sclerosis

(2019) Edoardo Galli et al.   NATURE MEDICINE

Cardiovascular Disease-Related Serum Proteins in Workers Occupationally Exposed to Polycyclic Aromatic Hydrocarbons

(2019) Ayman Alhamdow et al.   TOXICOLOGICAL SCIENCES

Compounds of PAH mixtures dependent interaction between multiple signaling pathways in granulosa tumour cells

(2019) K. Zajda et al.   TOXICOLOGY LETTERS

Oxidative stress and biomarker responses in the Atlantic halibut after long term exposure to elevated CO2 and a range of temperatures

(2019) B. Carney Almroth et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY

Osteotoxicity of 3-methylcholanthrene in fish

(2018) Vincent Laizé et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Biotransformation of Benzo[a]pyrene by Three Rainbow Trout (Onchorhynchus mykiss) Cell Lines and Extrapolation To Derive a Fish Bioconcentration Factor

(2018) Julita Stadnicka-Michalak et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Functional and structural characterization of zebrafish ASC

(2018) Yajuan Li et al.   FEBS Journal

Serum biochemistry, histology and transcriptomic profile analysis reflect liver inflammation and damage following dietary histamine supplementation in yellow catfish ( Pelteobagrus fulvidraco )

(2018) Wei Li et al.   FISH & SHELLFISH IMMUNOLOGY

Intracellular TLR22 acts as an inflammation equalizer via suppression of NF-κB and selective activation of MAPK pathway in fish

(2018) Xu Ding et al.   FISH & SHELLFISH IMMUNOLOGY

Identification and Characterization of Novel Receptor-Interacting Serine/Threonine‐Protein Kinase 2 Inhibitors Using Structural Similarity Analysis

(2018) Mohamed Salla et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Assessing the impact of benzo[ a ]pyrene with the in vitro fish gut model: An integrated approach for eco-genotoxicological studies

(2018) Laura M. Langan et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Interleukin-6: designing specific therapeutics for a complex cytokine

(2018) Christoph Garbers et al.   NATURE REVIEWS DRUG DISCOVERY

Comparative transcriptome analysis of the swimbladder reveals expression signatures in response to low oxygen stress in channel catfish, Ictalurus punctatus.

(2018) Yujia Yang et al.   PHYSIOLOGICAL GENOMICS

Glutathione S-Transferase Protein Expression in Different Life Stages of Zebrafish (Danio rerio)

(2018) Alena Tierbach et al.   TOXICOLOGICAL SCIENCES

Co-exposure to environmental carcinogens in vivo induces neoplasia-related hallmarks in low-genotoxicity events, even after removal of insult

(2018) Marta Martins et al.   Scientific Reports

Recognition of Lipopolysaccharide and Activation of NF-κB by Cytosolic Sensor NOD1 in Teleost Fish

(2018) Dekun Bi et al.   Frontiers in Immunology

Growth, energy metabolism and transcriptomic responses in Chinese mitten crab (Eriocheir sinensis) to benzo[α]pyrene (BaP) toxicity

(2018) Na Yu et al.   AQUATIC TOXICOLOGY

Comparative transcriptome analysis between the short-term stress and long-term adaptation of the Ruditapes philippinarum in response to benzo[a]pyrene

(2018) Hongdan Wang et al.   AQUATIC TOXICOLOGY

Monitoring sublethal changes in fish physiology following exposure to a light, unweathered crude oil

(2018) Sharon E. Hook et al.   AQUATIC TOXICOLOGY

The NOD1 and NOD2 in mandarinfish (Siniperca chuatsi): molecular characterization, tissue distribution, and expression analysis

(2018) Tiantian Gu et al.   BMC GENETICS

TAK1 of black carp positively regulates IRF7-mediated antiviral signaling in innate immune activation

(2018) Chanyuan Wang et al.   FISH & SHELLFISH IMMUNOLOGY

Characterization of an NLRP1 Inflammasome from Zebrafish Reveals a Unique Sequential Activation Mechanism Underlying Inflammatory Caspases in Ancient Vertebrates

(2018) Jiang-yuan Li et al.   JOURNAL OF IMMUNOLOGY

Edwardsiella piscicida virulence effector trxlp promotes the NLRC4 inflammasome activation during infection

(2018) Wenting Xu et al.   MICROBIAL PATHOGENESIS

Development of a gill assay library for ecological proteomics of threespine sticklebacks (Gasterosteus aculeatus)

(2018) Johnathon Li et al.   MOLECULAR & CELLULAR PROTEOMICS

Transcriptomic analysis reveal an efficient osmoregulatory system in Siberian sturgeon Acipenser baeri in response to salinity stress

(2018) Baoying Guo et al.   Scientific Reports

Genome sequence of walking catfish (Clarias batrachus) provides insights into terrestrial adaptation

(2018) Ning Li et al.   BMC GENOMICS

Distribution pattern and health risk assessment of polycyclic aromatic hydrocarbons in the water and sediment of Algoa Bay, South Africa

(2018) A. O. Adeniji et al.   ENVIRONMENTAL GEOCHEMISTRY AND HEALTH

Molecular cloning and functional characterization of TRAF6 and TAK1 in rainbow trout, Oncorhynchus mykiss

(2018) Ju Hye Jang et al.   FISH & SHELLFISH IMMUNOLOGY

Adipose tissue contributes to hepatic pro-inflammatory response when dietary fish oil is replaced by vegetable oil in large yellow croaker (Larimichthys crocea): An ex vivo study

(2018) Peng Tan et al.   FISH & SHELLFISH IMMUNOLOGY

A CARD9 Founder Mutation Disrupts NF-κB Signaling by Inhibiting BCL10 and MALT1 Recruitment and Signalosome Formation

(2018) Marieke De Bruyne et al.   Frontiers in Immunology

Transcriptomic analysis reveals dose-dependent modes of action of benzo(a)pyrene in polar cod (Boreogadus saida)

(2018) You Song et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Identification of the full 26 cytochrome P450 (CYP) genes and analysis of their expression in response to benzo[α]pyrene in the marine rotifer Brachionus rotundiformis

(2018) Jeonghoon Han et al.   Comparative Biochemistry and Physiology D-Genomics & Proteomics

Benzo( a )pyrene-induced a mitochondria-independent apoptosis of liver in juvenile Chinese rare minnows ( Gobiocypris rarus )

(2017) Jinmiao Zha et al.   ENVIRONMENTAL POLLUTION

Transcriptional response in rainbow trout ( Oncorhynchus mykiss ) B cells and thrombocytes following in vivo exposure to benzo[a]pyrene

(2017) Laura J. Phalen et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Impact of molecular hydrogen treatments on the innate immune activity and survival of zebrafish ( Danio rerio ) challenged with Aeromonas hydrophila

(2017) Zhenyu Hu et al.   FISH & SHELLFISH IMMUNOLOGY

Physiological and immune response of juvenile rainbow trout to dietary bovine lactoferrin

(2017) Trinh Dinh Khuyen et al.   FISH & SHELLFISH IMMUNOLOGY

Transcriptome analysis of immune response against Vibrio harveyi infection in orange-spotted grouper ( Epinephelus coioides )

(2017) Shun Maekawa et al.   FISH & SHELLFISH IMMUNOLOGY

Ras oncogene and Hypoxia-inducible factor-1 alpha (hif-1α) expression in the Amazon fish Colossoma macropomum (Cuvier, 1818) exposed to benzo[a]pyrene.

(2017) Grazyelle Sebrenski da Silva et al.   GENETICS AND MOLECULAR BIOLOGY

Developing a Black Carbon-Substituted Multimedia Model for Simulating the PAH Distributions in Urban Environments

(2017) Chunhui Wang et al.   Scientific Reports

The H7N9 influenza A virus infection results in lethal inflammation in the mammalian host via the NLRP3-caspase-1 inflammasome

(2017) Rongrong Ren et al.   Scientific Reports

Dietary selenium disrupts hepatic triglyceride stores and transcriptional networks associated with growth and Notch signaling in juvenile rainbow trout

(2016) Rosalinda Knight et al.   AQUATIC TOXICOLOGY

Validation of research trajectory 1 of an Exposome framework: Exposure to benzo(a)pyrene confers enhanced susceptibility to bacterial infection

(2016) Ryan S. Clark et al.   ENVIRONMENTAL RESEARCH

Characterisation of transcriptional responses to dioxins and dioxin-like contaminants in roach ( Rutilus rutilus ) using whole transcriptome analysis

(2016) Markus Brinkmann et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Chronic Administration of Benzo(a)pyrene Induces Memory Impairment and Anxiety-Like Behavior and Increases of NR2B DNA Methylation

(2016) Wenping Zhang et al.   PLoS One

Effects of Anthropogenic Pollution on the Oxidative Phosphorylation Pathway of Hepatocytes from Natural Populations of Fundulus heteroclitus

(2015) Xiao Du et al.   AQUATIC TOXICOLOGY

Comparative transcriptomic analyses to scrutinize the assumption that genotoxic PAHs exert effects via a common mode of action

(2015) S. Labib et al.   ARCHIVES OF TOXICOLOGY

Relationship between biomarkers and endocrine-disrupting compounds in wild Girardnichthys viviparus from two lakes with different degrees of pollution

(2015) Hugo F. Olivares-Rubio et al.   ECOTOXICOLOGY

Polycyclic Aromatic Hydrocarbons: From Metabolism to Lung Cancer

(2015) Bhagavatula Moorthy et al.   TOXICOLOGICAL SCIENCES

Tyrosine glycosylation of Rho by Yersinia toxin impairs blastomere cell behaviour in zebrafish embryos

(2015) Thomas Jank et al.   Nature Communications

Multigenerational effects of benzo[a]pyrene exposure on survival and developmental deformities in zebrafish larvae

(2014) Jone Corrales et al.   AQUATIC TOXICOLOGY

EROD activity and antioxidant defenses of sea bass (Dicentrarchus labrax) after an in vivo chronic hydrocarbon pollution followed by a post-exposure period

(2014) Morgane Danion et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Pro-Inflammatory Cytokines in the Serum of Silver Catfish (Rhamdia quelen) Naturally Infected byClinostomum complanatum: A Preliminary Study

(2014) Horacio Luis de Lima et al.   JOURNAL OF PARASITOLOGY

Pollution biomonitoring in the Bizerte lagoon (Tunisia), using combined chemical and biomarker analyses in grass goby, Zosterisessor ophiocephalus (Teleostei, Gobiidae)

(2014) Badreddine Barhoumi et al.   MARINE ENVIRONMENTAL RESEARCH

In-situ partitioning and bioconcentration of polycyclic aromatic hydrocarbons among water, suspended particulate matter, and fish in the Dongjiang and Pearl Rivers and the Pearl River Estuary, China

(2014) Haiyan Li et al.   MARINE POLLUTION BULLETIN

AHR2-Mediated Transcriptomic Responses Underlying the Synergistic Cardiac Developmental Toxicity of PAHs

(2014) Nishad Jayasundara et al.   TOXICOLOGICAL SCIENCES

Analysis of immune gene expression modulated by benzo[a]pyrene in head kidney of olive flounder (Paralichthys olivaceus)

(2013) Deokhwe Hur et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY

NOD1 and NOD2 receptors in mrigal (Cirrhinus mrigala): Inductive expression and downstream signalling in ligand stimulation and bacterial infections

(2013) Banikalyan Swain et al.   JOURNAL OF BIOSCIENCES

The zebrafish reference genome sequence and its relationship to the human genome

(2013) Kerstin Howe et al.   NATURE

Soybean β-Conglycinin Induces Inflammation and Oxidation and Causes Dysfunction of Intestinal Digestion and Absorption in Fish

(2013) Jin-Xiu Zhang et al.   PLoS One

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

Sweeten PAMPs: role of sugar complexed PAMPs in innate immunity and vaccine biology

(2013) Ranjeet Singh Mahla   Frontiers in Immunology

Exposure of primary porcine urothelial cells to benzo(a)pyrene: in vitro uptake, intracellular concentration, and biological response

(2012) Nisha Verma et al.   ARCHIVES OF TOXICOLOGY

Evaluation of biomarker potential of cytochrome P450 1A (CYP1A) gene in the marine medaka, Oryzias melastigma exposed to water-accommodated fractions (WAFs) of Iranian crude oil

(2012) Ryeo-Ok Kim et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

(2012) Cole Trapnell et al.   Nature Protocols

Effect of cadmium on glutathione S-transferase and metallothionein gene expression in coho salmon liver, gill and olfactory tissues

(2011) Herbert M. Espinoza et al.   AQUATIC TOXICOLOGY

RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

(2011) Bo Li et al.   BMC BIOINFORMATICS

Gene expression analysis of ABC efflux transporters, CYP1A and GSTα in Nile tilapia after exposure to benzo(a)pyrene

(2011) Joana Costa et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

Pathogen recognition receptors in channel catfish: I. Identification, phylogeny and expression of NOD-like receptors

(2011) K.V. Rajendran et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

State of the union between metabolism and the immune system in type 2 diabetes

(2011) B S Nikolajczyk et al.   GENES AND IMMUNITY

Improving RNA-Seq expression estimates by correcting for fragment bias

(2011) Adam Roberts et al.   GENOME BIOLOGY

Characterization of the recalcitrant CYP1 phenotype found in Atlantic killifish (Fundulus heteroclitus) inhabiting a Superfund site on the Elizabeth River, VA

(2010) Lauren P. Wills et al.   AQUATIC TOXICOLOGY

Gene ontology analysis for RNA-seq: accounting for selection bias

(2010) Matthew D Young et al.   GENOME BIOLOGY

Hepatic and vascular mRNA expression in adult zebrafish (Danio rerio) following exposure to benzo-a-pyrene and 2,3,7,8-tetrachlorodibenzo-p-dioxin

(2009) Brandie Bugiak et al.   AQUATIC TOXICOLOGY

Structure and expression pattern of teleost caspase recruitment domain (CARD) containing proteins that are potentially involved in NF-κB signalling

(2009) M.X. Chang et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Unleashing the therapeutic potential of NOD-like receptors

(2009) Kaoru Geddes et al.   NATURE REVIEWS DRUG DISCOVERY

Mercury toxicity in livers of northern pike (Esox lucius) from Isle Royale, USA

(2008) Paul E. Drevnick et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

MAPK regulate p53-dependent cell death induced by benzo[a]pyrene: Involvement of p53 phosphorylation and acetylation

(2008) T. Lin et al.   TOXICOLOGY

β-Naphthoflavone and benzo(a)pyrene treatment affect liver intermediary metabolism and plasma cortisol levels in rainbow trout Oncorhynchus mykiss

(2007) Adrián Tintos et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY