Curcumin suppresses tumor growth of gemcitabine-resistant non-small cell lung cancer by regulating lncRNA-MEG3 and PTEN signaling

Shikonin suppresses NEAT1 and Akt signaling in treating paclitaxel-resistant non-small cell of lung cancer

(2020) Farong Zang et al.   MOLECULAR MEDICINE

Anticancer activity of Polyphyllin I in nasopharyngeal carcinoma by modulation of lncRNA ROR and P53 signaling

(2019) Feilong Hong et al.   JOURNAL OF DRUG TARGETING

The role of exosomal noncoding RNAs in cancer

(2019) Yan Xie et al.   Molecular Cancer

Curcumin: New Insights into an Ancient Ingredient against Cancer

(2019) Ella Willenbacher et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

MEG3 interacted with miR‐494 to repress bladder cancer progression through targeting PTEN

(2019) Guang Shan et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Curcumin overcome primary gefitinib resistance in non-small-cell lung cancer cells through inducing autophagy-related cell death

(2019) Ping Chen et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Maternally expressed gene 3 (MEG3): A tumor suppressor long non coding RNA

(2019) Soudeh Ghafouri-Fard et al.   BIOMEDICINE & PHARMACOTHERAPY

Curcumin and Cancer

(2019) Giordano et al.   Nutrients

Long noncoding RNA MEG3 inhibits proliferation of chronic myeloid leukemia cells by sponging microRNA21

(2018) Ziye Li et al.   BIOMEDICINE & PHARMACOTHERAPY

Antitumor activity of curcumin by modulation of apoptosis and autophagy in human lung cancer A549 cells through inhibiting PI3K/Akt/mTOR pathway

(2018) Furong Liu et al.   ONCOLOGY REPORTS

Long noncoding RNA MEG3 suppresses liver cancer cells growth through inhibiting β-catenin by activating PKM2 and inactivating PTEN

(2018) Qidi Zheng et al.   Cell Death & Disease

Polyphyllin I modulates MALAT1/STAT3 signaling to induce apoptosis in gefitinib-resistant non-small cell lung cancer

(2018) Qi Yang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

A mono-carbonyl analog of curcumin induces apoptosis in drug-resistant EGFR-mutant lung cancer through the generation of oxidative stress and mitochondrial dysfunction

(2018) Xuanxuan Dai et al.   Cancer Management and Research

LncRNA MEG3 impacts proliferation, invasion, and migration of ovarian cancer cells through regulating PTEN

(2018) Juelan Wang et al.   INFLAMMATION RESEARCH

LncRNAs in Cancer: another layer of complexity

(2018) Jaqueline Carvalho Oliveira et al.   JOURNAL OF GENE MEDICINE

Down-regulation of long non-coding RNA MEG3 indicates an unfavorable prognosis in non-small cell lung cancer: Evidence from the GEO database

(2017) Zichao Zhang et al.   GENE

The inhibitory effect of MEG3/miR-214/AIFM2 axis on the growth of T-cell lymphoblastic lymphoma

(2017) Fang-Yi Fan et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Polyphyllin VII increases sensitivity to gefitinib by modulating the elevation of P21 in acquired gefitinib resistant non-small cell lung cancer

(2017) Honggang Wang et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Exosomes derived from gemcitabine-resistant cells transfer malignant phenotypic traits via delivery of miRNA-222-3p

(2017) Feng Wei et al.   Molecular Cancer

Curcumin analog L48H37 induces apoptosis through ROS-mediated endoplasmic reticulum stress and STAT3 pathways in human lung cancer cells

(2017) Chen Feng et al.   MOLECULAR CARCINOGENESIS

Curcumin Suppresses Lung Cancer Stem Cells via Inhibiting Wnt/β-catenin and Sonic Hedgehog Pathways

(2017) Jian-Yun Zhu et al.   PHYTOTHERAPY RESEARCH

LncRNA MEG3 enhances cisplatin sensitivity in non-small cell lung cancer by regulating miR-21-5p/SOX7 axis

(2017) Pei Wang et al.   OncoTargets and Therapy

Potential applications of MEG3 in cancer diagnosis and prognosis

(2017) Yuqing He et al.   Oncotarget

Discovery of New Monocarbonyl Ligustrazine–Curcumin Hybrids for Intervention of Drug-Sensitive and Drug-Resistant Lung Cancer

(2016) Yong Ai et al.   JOURNAL OF MEDICINAL CHEMISTRY

Paris Saponins enhance radiosensitivity in a gefitinib-resistant lung adenocarcinoma cell line by inducing apoptosis and G2/M cell cycle phase arrest

(2016) PENG-JUN ZHAO et al.   Molecular Medicine Reports

Anti-cancer effects of curcumin on lung cancer through the inhibition of EZH2 and NOTCH1

(2016) Guo-Qing Wu et al.   Oncotarget

Paris Saponin I Sensitizes Gastric Cancer Cell Lines to Cisplatin via Cell Cycle Arrest and Apoptosis

(2016) Shuichuan Song et al.   MEDICAL SCIENCE MONITOR

Anticancer Effects of Paris Saponins by Apoptosis and PI3K/AKT Pathway in Gefitinib-Resistant Non-Small Cell Lung Cancer

(2016) XinHai Zhu et al.   MEDICAL SCIENCE MONITOR

Epigenetic repression of long non-coding RNA MEG3 mediated by DNMT1 represses the p53 pathway in gliomas

(2015) JIA LI et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Downregulation of Meg3 enhances cisplatin resistance of lung cancer cells through activation of the WNT/β-catenin signaling pathway

(2015) YANG XIA et al.   Molecular Medicine Reports

Dendrosomal curcumin increases expression of the long non-coding RNA gene MEG3 via up-regulation of epi-miRs in hepatocellular cancer

(2015) Mina Zamani et al.   PHYTOMEDICINE

The Long Noncoding RNA MEG3 Contributes to Cisplatin Resistance of Human Lung Adenocarcinoma

(2015) Jing Liu et al.   PLoS One

Inhibition of cell proliferation by mild hyperthermia at 43°C with Paris Saponin I in the lung adenocarcinoma cell line PC-9

(2014) PENGJUN ZHAO et al.   Molecular Medicine Reports

Paris saponin I induces apoptosis via increasing the Bax/Bcl-2 ratio and caspase-3 expression in gefitinib-resistant non-small cell lung cancer in vitro and in vivo

(2014) HAO JIANG et al.   Molecular Medicine Reports

Effect of Paris saponin I on radiosensitivity in a gefitinib-resistant lung adenocarcinoma cell line

(2014) HAO JIANG et al.   Oncology Letters

Curcumin reverses cis-platin resistance and promotes human lung adenocarcinoma A549/DDP cell apoptosis through HIF-1α and caspase-3 mechanisms

(2012) Ming-Xiang Ye et al.   PHYTOMEDICINE