Mitochondrial iron metabolism and its role in diseases

Mitochondrial superoxide/hydrogen peroxide: An emerging therapeutic target for metabolic diseases

(2020) Jialong Yan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Ferritinophagy activation and sideroflexin1-dependent mitochondria iron overload is involved in apelin-13-induced cardiomyocytes hypertrophy

(2019) Mingzhu Tang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Iron homeostasis and iron-regulated ROS in cell death, senescence and human diseases

(2019) Toshitaka Nakamura et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Transferrin and transferrin receptors update

(2018) Hiroshi Kawabata   FREE RADICAL BIOLOGY AND MEDICINE

Metal Ion Effects on Aβ and Tau Aggregation

(2018) Anne Kim et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

ROS-Autophagy pathway mediates monocytes-human umbilical vein endothelial cells adhesion induced by apelin-13

(2018) Meiqing Liu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Handling heme: The mechanisms underlying the movement of heme within and between cells

(2018) Rebecca K. Donegan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Molecular pathophysiology and genetic mutations in congenital sideroblastic anemia

(2018) Tohru Fujiwara et al.   FREE RADICAL BIOLOGY AND MEDICINE

Ferritinophagy/ferroptosis: Iron-related newcomers in human diseases

(2018) Mingzhu Tang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Mitochondrial Iron Metabolism and Its Role in Neurodegeneration

(2017) Maxx P. Horowitz et al.   JOURNAL OF ALZHEIMERS DISEASE

Erythroid cell mitochondria receive endosomal iron by a “kiss-and-run” mechanism

(2016) Amel Hamdi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Mitochondria and Cancer

(2016) Sejal Vyas et al.   CELL

Iron chelation in the treatment of neurodegenerative diseases

(2016) Petr Dusek et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Study of Glycine and Folic Acid Supplementation to Ameliorate Transfusion Dependence in Congenital SLC25A38 Mutated Sideroblastic Anemia

(2016) Marissa A. LeBlanc et al.   PEDIATRIC BLOOD & CANCER

Mitochondria and Iron: current questions

(2016) Bibbin T. Paul et al.   Expert Review of Hematology

Glycine and Folate Ameliorate Models of Congenital Sideroblastic Anemia

(2016) J. Pedro Fernández-Murray et al.   PLoS Genetics

Iron –sulfur cluster biogenesis in mammalian cells: New insights into the molecular mechanisms of cluster delivery

(2015) Nunziata Maio et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Mitochondrial Genome Acquisition Restores Respiratory Function and Tumorigenic Potential of Cancer Cells without Mitochondrial DNA

(2015) An S. Tan et al.   Cell Metabolism

A Heme Oxygenase-1 Transducer Model of Degenerative and Developmental Brain Disorders

(2015) Hyman Schipper et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mitochondrial iron homeostasis and its dysfunctions in neurodegenerative disorders

(2015) Natalia P. Mena et al.   MITOCHONDRION

Heme Enzyme Structure and Function

(2014) Thomas L. Poulos   CHEMICAL REVIEWS

β-Amyloid Precursor Protein Does Not Possess Ferroxidase Activity but Does Stabilize the Cell Surface Ferrous Iron Exporter Ferroportin

(2014) Bruce X. Wong et al.   PLoS One

Mitochondria and Metabolic Homeostasis

(2013) Zhiyong Cheng et al.   ANTIOXIDANTS & REDOX SIGNALING

Fixing frataxin: ‘ironing out’ the metabolic defect in Friedreich's ataxia

(2013) A Anzovino et al.   BRITISH JOURNAL OF PHARMACOLOGY

Frataxin: a protein in search for a function

(2013) Annalisa Pastore et al.   JOURNAL OF NEUROCHEMISTRY

Enhanced Brain Delivery of Deferasirox–Lactoferrin Conjugates for Iron Chelation Therapy in Neurodegenerative Disorders: In Vitro and in Vivo Studies

(2013) Golnaz Kamalinia et al.   MOLECULAR PHARMACEUTICS

Enhanced Heme Function and Mitochondrial Respiration Promote the Progression of Lung Cancer Cells

(2013) Jagmohan Hooda et al.   PLoS One

Emerging Paradigms for Complex Iron-Sulfur Cofactor Assembly and Insertion

(2012) John W. Peters et al.   Annual Review of Biochemistry

Mammalian Iron Homeostasis in Health and Disease: Uptake, Storage, Transport, and Molecular Mechanisms of Action

(2012) Alfons Lawen et al.   ANTIOXIDANTS & REDOX SIGNALING

Biogenesis of iron-sulfur clusters in mammalian cells: new insights and relevance to human disease

(2012) T. A. Rouault   Disease Models & Mechanisms

Brain iron accumulation in aging and neurodegenerative disorders

(2012) Jesper Hagemeier et al.   Expert Review of Neurotherapeutics

Antioxidant role of amyloid β protein in cell-free and biological systems: implication for the pathogenesis of Alzheimerdisease

(2012) Maitrayee Sinha et al.   FREE RADICAL BIOLOGY AND MEDICINE

Metal dyshomeostasis and oxidative stress in Alzheimer’s disease

(2012) Mark A. Greenough et al.   NEUROCHEMISTRY INTERNATIONAL

Mitochondrial Mayhem: The Mitochondrion as a Modulator of Iron Metabolism and Its Role in Disease

(2011) Michael Li-Hsuan Huang et al.   ANTIOXIDANTS & REDOX SIGNALING

Iron(II) Binding to Amyloid-β, the Alzheimer’s Peptide

(2011) Fatima Bousejra-ElGarah et al.   INORGANIC CHEMISTRY

Eukaryotic DNA polymerases require an iron-sulfur cluster for the formation of active complexes

(2011) Daili J A Netz et al.   Nature Chemical Biology

The Role of CyaY in Iron Sulfur Cluster Assembly on the E. coli IscU Scaffold Protein

(2011) Clara Iannuzzi et al.   PLoS One

Transferrin-iron routing to the cytosol and mitochondria as studied by live and real-time fluorescence

(2010) Maya Shvartsman et al.   BIOCHEMICAL JOURNAL

Human Iron−Sulfur Cluster Assembly, Cellular Iron Homeostasis, and Disease

(2010) Hong Ye et al.   BIOCHEMISTRY

Human Frataxin Is an Allosteric Switch That Activates the Fe−S Cluster Biosynthetic Complex

(2010) Chi-Lin Tsai et al.   BIOCHEMISTRY

Two to Tango: Regulation of Mammalian Iron Metabolism

(2010) Matthias W. Hentze et al.   CELL

Hereditary sideroblastic anemia: pathophysiology and gene mutations

(2010) Hideo Harigae et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Mitochondrial iron trafficking and the integration of iron metabolism between the mitochondrion and cytosol

(2010) D. R. Richardson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutation in Pyrroline-5-Carboxylate Reductase 1 Gene in Families with Cutis Laxa Type 2

(2009) Duane L. Guernsey et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Biophysical Characterization of the Iron in Mitochondria from Atm1p-DepletedSaccharomyces cerevisiae

(2009) Ren Miao et al.   BIOCHEMISTRY

The ins and outs of mitochondrial iron-loading: the metabolic defect in Friedreich’s ataxia

(2009) Des R. Richardson et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Function and biogenesis of iron–sulphur proteins

(2009) Roland Lill   NATURE

Mutations in mitochondrial carrier family gene SLC25A38 cause nonsyndromic autosomal recessive congenital sideroblastic anemia

(2009) Duane L Guernsey et al.   NATURE GENETICS

Bacterial frataxin CyaY is the gatekeeper of iron-sulfur cluster formation catalyzed by IscS

(2009) Salvatore Adinolfi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease

(2009) J. Yao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Elucidation of the mechanism of mitochondrial iron loading in Friedreich's ataxia by analysis of a mouse mutant

(2009) M. L.-H. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The power plant of the cell is also a smithy: The emerging role of mitochondria in cellular iron homeostasis

(2008) Alex D. Sheftel et al.   ANNALS OF MEDICINE

Maturation of Iron-Sulfur Proteins in Eukaryotes: Mechanisms, Connected Processes, and Diseases

(2008) Roland Lill et al.   Annual Review of Biochemistry

Systemic Iron Homeostasis and the Iron-Responsive Element/Iron-Regulatory Protein (IRE/IRP) Regulatory Network

(2008) Martina U. Muckenthaler et al.   Annual Review of Nutrition

Mitochondrial ferritin limits oxidative damage regulating mitochondrial iron availability: hypothesis for a protective role in Friedreich ataxia

(2008) A. Campanella et al.   HUMAN MOLECULAR GENETICS

Differential Regulation of Dynein and Kinesin Motor Proteins by Tau

(2008) R. Dixit et al.   SCIENCE

Characterization of Copper Interactions with Alzheimer Amyloid β Peptides

(2003) Craig S. Atwood et al.   JOURNAL OF NEUROCHEMISTRY