KPT-330 Prevents Aortic Valve Calcification via a Novel C/EBPβ Signaling Pathway

A two phase regulation of bone regeneration: IL-17F mediates osteoblastogenesis via C/EBP-β in vitro

(2018) Yufa Wang et al.   BONE

Calcific Aortic Valve Disease: a Developmental Biology Perspective

(2018) Punashi Dutta et al.   Current Cardiology Reports

Cadherin-11 Overexpression Induces Extracellular Matrix Remodeling and Calcification in Mature Aortic ValvesHighlights

(2016) Derek C. Sung et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Role of Noncanonical Wnt Signaling Pathway in Human Aortic Valve CalcificationHighlights

(2016) Isabella Albanese et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Loss of Axin2 results in impaired heart valve maturation and subsequent myxomatous valve disease

(2016) Alexia Hulin et al.   CARDIOVASCULAR RESEARCH

WNT/β-catenin signaling promotes VSMCs to osteogenic transdifferentiation and calcification through directly modulating Runx2 gene expression

(2016) Ting Cai et al.   EXPERIMENTAL CELL RESEARCH

Involvement of Immune Cell Network in Aortic Valve Stenosis: Communication between Valvular Interstitial Cells and Immune Cells

(2016) Seung Hyun Lee et al.   Immune Network

Cadherin-11 coordinates cellular migration and extracellular matrix remodeling during aortic valve maturation

(2015) Caitlin J. Bowen et al.   DEVELOPMENTAL BIOLOGY

Pharmacologic Wnt Inhibition Reduces Proliferation, Survival, and Clonogenicity of Glioblastoma Cells

(2015) Ulf D. Kahlert et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Clinical translation of nuclear export inhibitors in cancer

(2014) William T. Senapedis et al.   SEMINARS IN CANCER BIOLOGY

Genome-wide studies in multiple myeloma identify XPO1/CRM1 as a critical target validated using the selective nuclear export inhibitor KPT-276

(2013) J Schmidt et al.   LEUKEMIA

Circulation : Clinical Summaries

(2012)   CIRCULATION

Differential activation of valvulogenic, chondrogenic, and osteogenic pathways in mouse models of myxomatous and calcific aortic valve disease

(2012) Jonathan D. Cheek et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Marine ecology: Attack of the blobs

(2012) Mark Schrope   NATURE

Differences in valvular and vascular cell responses to strain in osteogenic media

(2011) Zannatul Ferdous et al.   BIOMATERIALS

Cell–Matrix Interactions in the Pathobiology of Calcific Aortic Valve Disease

(2011) Jan-Hung Chen et al.   CIRCULATION RESEARCH

Association of Serum Phosphate Levels With Aortic Valve Sclerosis and Annular Calcification

(2011) Jason P. Linefsky et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Evidence for Active Regulation of Pro-Osteogenic Signaling in Advanced Aortic Valve Disease

(2010) Jordan D. Miller et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases

(2009) Bryan T. MacDonald et al.   DEVELOPMENTAL CELL

Transcriptional Regulation of Heart Valve Progenitor Cells

(2009) Santanu Chakraborty et al.   PEDIATRIC CARDIOLOGY

Prognosis and Risk Factors in Patients With Asymptomatic Aortic Stenosis and Their Modulation by Atorvastatin (20 mg)

(2008) Wolfgang Dichtl et al.   AMERICAN JOURNAL OF CARDIOLOGY

Stage-Related Effect of Statin Treatment on the Progression of Aortic Valve Sclerosis and Stenosis

(2008) Francesco Antonini-Canterin et al.   AMERICAN JOURNAL OF CARDIOLOGY

Oxidation, Inflammation, and Aortic Valve Calcification

(2008) Dwight A. Towler   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Intensive Lipid Lowering with Simvastatin and Ezetimibe in Aortic Stenosis

(2008) Anne B. Rossebø et al.   NEW ENGLAND JOURNAL OF MEDICINE