miR-33 Silencing Reprograms the Immune Cell Landscape in Atherosclerotic Plaques

Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage

(2019) Dvir Aran et al.   NATURE IMMUNOLOGY

Lipid-Associated Macrophages Control Metabolic Homeostasis in a Trem2-Dependent Manner

(2019) Diego Adhemar Jaitin et al.   CELL

Single-cell immune landscape of human atherosclerotic plaques

(2019) Dawn M. Fernandez et al.   NATURE MEDICINE

Deletion of Macrophage Low-Density Lipoprotein Receptor-Related Protein 1 (LRP1) Accelerates Atherosclerosis Regression and Increases CCR7 Expression in Plaque Macrophages

(2018) Paul A. Mueller et al.   CIRCULATION

Atlas of the Immune Cell Repertoire in Mouse Atherosclerosis Defined by Single-Cell RNA-Sequencing and Mass CytometryNovelty and Significance

(2018) Holger Winkels et al.   CIRCULATION RESEARCH

How Oxidized Low-Density Lipoprotein Activates Inflammatory Responses

(2018) Jillian P. Rhoads et al.   CRITICAL REVIEWS IN IMMUNOLOGY

Inflammatory Ly6Chi monocytes and their conversion to M2 macrophages drive atherosclerosis regression

(2017) Karishma Rahman et al.   JOURNAL OF CLINICAL INVESTIGATION

E-Selectin Inhibition Mitigates Splenic HSC Activation and Myelopoiesis in Hypercholesterolemic Mice With Myocardial InfarctionHighlights

(2016) Partha Dutta et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

miRNA Targeting of Oxysterol-Binding Protein-Like 6 Regulates Cholesterol Trafficking and EffluxSignificance

(2016) Mireille Ouimet et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Interferons as Essential Modulators of AtherosclerosisSignificance

(2015) Marieke C.S. Boshuizen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Nonclassical Patrolling Monocyte Function in the Vasculature

(2015) G. Thomas et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Macrophage Mitochondrial Energy Status Regulates Cholesterol Efflux and Is Enhanced by Anti-miR33 in AtherosclerosisNovelty and Significance

(2015) Denuja Karunakaran et al.   CIRCULATION RESEARCH

MicroRNA-33–dependent regulation of macrophage metabolism directs immune cell polarization in atherosclerosis

(2015) Mireille Ouimet et al.   JOURNAL OF CLINICAL INVESTIGATION

Alternatively activated macrophages derived from monocytes and tissue macrophages are phenotypically and functionally distinct

(2014) U. M. Gundra et al.   BLOOD

miR33 Inhibition Overcomes Deleterious Effects of Diabetes Mellitus on Atherosclerosis Plaque Regression in Mice

(2014) Emilie Distel et al.   CIRCULATION RESEARCH

The Influence of Innate and Adaptive Immune Responses on Atherosclerosis

(2013) Joseph L. Witztum et al.   Annual Review of Pathology-Mechanisms of Disease

Therapeutic Silencing of MicroRNA-33 Inhibits the Progression of Atherosclerosis in Ldlr −/− Mice—Brief Report

(2013) Noemi Rotllan et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Rapid regression of atherosclerosis with MTP inhibitor treatment

(2013) Bernd Hewing et al.   ATHEROSCLEROSIS

Hyperglycemia Promotes Myelopoiesis and Impairs the Resolution of Atherosclerosis

(2013) Prabhakara R. Nagareddy et al.   Cell Metabolism

miR-33 controls the expression of biliary transporters, and mediates statin- and diet-induced hepatotoxicity

(2012) Ryan M. Allen et al.   EMBO Molecular Medicine

Regression of Atherosclerosis Is Characterized by Broad Changes in the Plaque Macrophage Transcriptome

(2012) Jonathan E. Feig et al.   PLoS One

Dynamic Changes in Regulatory T Cells Are Linked to Levels of Diet-Induced Hypercholesterolemia

(2011) Elena Maganto-García et al.   CIRCULATION

Extramedullary Hematopoiesis Generates Ly-6C high Monocytes That Infiltrate Atherosclerotic Lesions

(2011) Clinton S. Robbins et al.   CIRCULATION

The Role of Retinoic Acid in Tolerance and Immunity

(2011) Jason A. Hall et al.   IMMUNITY

Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis

(2011) Katey J. Rayner et al.   JOURNAL OF CLINICAL INVESTIGATION

Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides

(2011) Katey J. Rayner et al.   NATURE

Mechanisms and consequences of efferocytosis in advanced atherosclerosis

(2009) Edward Thorp et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Rapid regression of atherosclerosis: insights from the clinical and experimental literature

(2008) Kevin Jon Williams et al.   Nature clinical practice. Cardiovascular medicine