Review: ER stress-induced cell death in osteoarthritic cartilage

Mechanistic insights in recov-ER-phagy: micro-ER-phagy to recover from stress

(2020) Marisa Loi et al.   Autophagy

High‐fat diet induces endoplasmic reticulum stress to promote chondrocyte apoptosis in mouse knee joints

(2020) Li Tan et al.   FASEB JOURNAL

ASK1 inhibition: a therapeutic strategy with multi-system benefits

(2020) Jacqueline M. Ogier et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Mechanisms, regulation and functions of the unfolded protein response

(2020) Claudio Hetz et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

IRE1 signaling pathway mediates protective autophagic response against manganese-induced neuronal apoptosis in vivo and in vitro

(2020) Chang Liu et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Autophagy as a modulator of cell death machinery

(2020) Masayuki Noguchi et al.   Cell Death & Disease

Bax Targeted by miR-29a Regulates Chondrocyte Apoptosis in Osteoarthritis

(2019) Guiqiang Miao et al.   Biomed Research International

MTORC1 coordinates the autophagy and apoptosis signaling in articular chondrocytes in osteoarthritic temporomandibular joint

(2019) Hongxu Yang et al.   Autophagy

4-Phenylbutyrate protects against atherosclerotic lesion growth by increasing the expression of HSP25 in macrophages and in the circulation of Apoe−/− mice

(2019) Edward G. Lynn et al.   FASEB JOURNAL

Accelerated post traumatic osteoarthritis in a dual injury murine model

(2019) K. McCulloch et al.   OSTEOARTHRITIS AND CARTILAGE

Protein quality control in the secretory pathway

(2019) Zhihao Sun et al.   JOURNAL OF CELL BIOLOGY

4-Phenylbutyric Acid Reduces Endoplasmic Reticulum Stress in Chondrocytes That Is Caused by Loss of the Protein Disulfide Isomerase ERp57

(2019) Yvonne Rellmann et al.   Oxidative Medicine and Cellular Longevity

DR4-Associated Death Receptor Signal Promotes Cartilage Damage in Patients With Kashin-Beck Disease

(2019) Shixun Wu et al.   Cartilage

Disposing of misfolded ER proteins: A troubled substrate's way out of the ER

(2019) Christina Oikonomou et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Direct visualization of degradation microcompartments at the ER membrane

(2019) Sahradha Albert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

4-Phenylbutyric acid presents therapeutic effect on osteoarthritis via inhibiting cell apoptosis and inflammatory response induced by endoplasmic reticulum stress

(2018) Yang-hua Tang et al.   BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

Carbamazepine reduces disease severity in a mouse model of metaphyseal chondrodysplasia type Schmid caused by a premature stop codon (Y632X) in the Col10a1 gene

(2018) Mitra Forouhan et al.   HUMAN MOLECULAR GENETICS

Paradoxical roles of ATF6α and ATF6β in modulating disease severity caused by mutations in collagen X

(2018) M. Forouhan et al.   MATRIX BIOLOGY

Structure of the yeast oligosaccharyltransferase complex gives insight into eukaryotic N-glycosylation

(2018) Rebekka Wild et al.   SCIENCE

Inhibiting the integrated stress response pathway prevents aberrant chondrocyte differentiation thereby alleviating chondrodysplasia

(2018) Cheng Wang et al.   eLife

An ultrastructural study of chondroptosis: programmed cell death in degenerative intervertebral discs in vivo

(2017) Li-Bo Jiang et al.   JOURNAL OF ANATOMY

Increased intracellular proteolysis reduces disease severity in an ER stress–associated dwarfism

(2017) Lorna A. Mullan et al.   JOURNAL OF CLINICAL INVESTIGATION

Mapping the ER Interactome: The P Domains of Calnexin and Calreticulin as Plurivalent Adapters for Foldases and Chaperones

(2017) Guennadi Kozlov et al.   STRUCTURE

Trehalose ameliorates oxidative stress-mediated mitochondrial dysfunction and ER stress via selective autophagy stimulation and autophagic flux restoration in osteoarthritis development

(2017) Qian Tang et al.   Cell Death & Disease

Necrotic pyknosis is a morphologically and biochemically distinct event from apoptotic pyknosis

(2016) Lin Hou et al.   JOURNAL OF CELL SCIENCE

Genetic Determinism of Primary Early-Onset Osteoarthritis

(2016) Juliette Aury-Landas et al.   TRENDS IN MOLECULAR MEDICINE

Osteoarthritis

(2016) Johanne Martel-Pelletier et al.   Nature Reviews Disease Primers

Tauroursodeoxycholic acid suppresses endoplasmic reticulum stress in the chondrocytes of patients with osteoarthritis

(2015) CHAO LIU et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Chondrocyte Apoptosis in the Pathogenesis of Osteoarthritis

(2015) Hyun Hwang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Stress-Induced Activation of Apoptosis Signal-Regulating Kinase 1 Promotes Osteoarthritis

(2015) Qian-Shi Zhang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Reglucosylation by UDP-glucose:glycoprotein glucosyltransferase 1 delays glycoprotein secretion but not degradation

(2015) Abla Tannous et al.   MOLECULAR BIOLOGY OF THE CELL

Cartilage-specific ablation of XBP1 signaling in mouse results in a chondrodysplasia characterized by reduced chondrocyte proliferation and delayed cartilage maturation and mineralization

(2015) T.L. Cameron et al.   OSTEOARTHRITIS AND CARTILAGE

Endoplasmic reticulum stress induces ligand-independent TNFR1-mediated necroptosis in L929 cells

(2015) S Saveljeva et al.   Cell Death & Disease

Increased Classical Endoplasmic Reticulum Stress Is Sufficient to Reduce Chondrocyte Proliferation Rate in the Growth Plate and Decrease Bone Growth

(2015) Louise H. W. Kung et al.   PLoS One

The many functions of the endoplasmic reticulum chaperones and folding enzymes

(2014) Laura Halperin et al.   IUBMB LIFE

c-Jun transactivates Puma gene expression to promote osteoarthritis

(2014) HUADING LU et al.   Molecular Medicine Reports

Endoplasmic reticulum stress-induced apoptosis contributes to articular cartilage degeneration via C/EBP homologous protein

(2014) Y. Uehara et al.   OSTEOARTHRITIS AND CARTILAGE

Regulation of inositol 1,4,5-trisphosphate receptors during endoplasmic reticulum stress

(2013) Santeri Kiviluoto et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Evolution of the unfolded protein response

(2013) Julie Hollien   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Epidemiology and burden of osteoarthritis

(2013) A. Litwic et al.   BRITISH MEDICAL BULLETIN

c-Jun N-terminal kinase – c-Jun pathway transactivates Bim to promote osteoarthritis

(2013) Zhiqiang Ye et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

Advanced glycation end-products induce endoplasmic reticulum stress in human aortic endothelial cells

(2013) Christos Adamopoulos et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

A novel transgenic mouse model of growth plate dysplasia reveals that decreased chondrocyte proliferation due to chronic ER stress is a key factor in reduced bone growth

(2013) B. Gualeni et al.   Disease Models & Mechanisms

Intracellular accumulation of advanced glycation end products induces apoptosis via endoplasmic reticulum stress in chondrocytes

(2013) Soichiro Yamabe et al.   FEBS Journal

Armet/Manf and Creld2 are components of a specialized ER stress response provoked by inappropriate formation of disulphide bonds: implications for genetic skeletal diseases

(2013) Claire L. Hartley et al.   HUMAN MOLECULAR GENETICS

The dual role of autophagy in chondrocyte responses in the pathogenesis of articular cartilage degeneration in osteoarthritis

(2013) JUN CHANG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Inflammatory markers associated with osteoarthritis after destabilization surgery in young mice with and without Receptor for Advanced Glycation End-products (RAGE)

(2013) D. Justin Larkin et al.   Frontiers in Physiology

Endoplasmic reticulum stress induces the expression of COX-2 through activation of eIF2α, p38-MAPK and NF-κB in advanced glycation end products stimulated human chondrocytes

(2012) Zafar Rasheed et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Hypertrophic Chondrocytes Have a Limited Capacity to Cope with Increases in Endoplasmic Reticulum Stress without Triggering the Unfolded Protein Response

(2012) Louise H. W. Kung et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

CHOP Potentially Co-Operates with FOXO3a in Neuronal Cells to Regulate PUMA and BIM Expression in Response to ER Stress

(2012) Arindam P. Ghosh et al.   PLoS One

The endoplasmic reticulum stress response in aging and age-related diseases

(2012) Marishka K. Brown et al.   Frontiers in Physiology

D469del-COMP Retention in Chondrocytes Stimulates Caspase-Independent Necroptosis

(2011) Françoise Coustry et al.   AMERICAN JOURNAL OF PATHOLOGY

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL

mTORC1 serves ER stress-triggered apoptosis via selective activation of the IRE1–JNK pathway

(2011) H Kato et al.   CELL DEATH AND DIFFERENTIATION

Enhanced apoptotic and reduced protective response in chondrocytes following endoplasmic reticulum stress in osteoarthritic cartilage

(2011) Koji Takada et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

The skeleton: a multi-functional complex organ. The growth plate chondrocyte and endochondral ossification

(2011) E J Mackie et al.   JOURNAL OF ENDOCRINOLOGY

TRB3 overexpression due to endoplasmic reticulum stress inhibits AKT kinase activation of tongue squamous cell carcinoma

(2011) Jing Zhang et al.   ORAL ONCOLOGY

Cell death of chondrocytes is a combination between apoptosis and autophagy during the pathogenesis of Osteoarthritis within an experimental model

(2010) M. Almonte-Becerril et al.   APOPTOSIS

Early-onset progressive osteoarthritis with hereditary progressive ophtalmopathy or Stickler syndrome

(2010) Tifenn Couchouron et al.   JOINT BONE SPINE

Structural Basis of Cyclophilin B Binding by the Calnexin/Calreticulin P-domain

(2010) Guennadi Kozlov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The p38 MAPK pathway is essential for skeletogenesis and bone homeostasis in mice

(2010) Matthew B. Greenblatt et al.   JOURNAL OF CLINICAL INVESTIGATION

The formation of intracellular glyceraldehyde-derived advanced glycation end-products and cytotoxicity

(2010) Jun-ichi Takino et al.   JOURNAL OF GASTROENTEROLOGY

Characterization of apoptosis in articular cartilage derived from the knee joints of patients with osteoarthritis

(2010) Giuseppe Musumeci et al.   KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY

Hypertrophic differentiation of chondrocytes in osteoarthritis: the developmental aspect of degenerative joint disorders

(2010) Rita Dreier   ARTHRITIS RESEARCH & THERAPY

Atf4 regulates chondrocyte proliferation and differentiation during endochondral ossification by activating Ihh transcription

(2009) W. Wang et al.   DEVELOPMENT

An Upstream Open Reading Frame Regulates Translation of GADD34 during Cellular Stresses That Induce eIF2α Phosphorylation

(2009) Yun-Young Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Advanced Osteoarthritis in Humans Is Associated With Altered Collagen VI Expression and Upregulation of ER-stress Markers Grp78 and Bag-1

(2009) Ashleigh E. Nugent et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

R992C (p.R1192C) Substitution in Collagen II Alters the Structure of Mutant Molecules and Induces the Unfolded Protein Response

(2009) Hye Jin Chung et al.   JOURNAL OF MOLECULAR BIOLOGY

Regulation of endoplasmic reticulum stress response by a BBF2H7-mediated Sec23a pathway is essential for chondrogenesis

(2009) Atsushi Saito et al.   NATURE CELL BIOLOGY

Targeted Induction of Endoplasmic Reticulum Stress Induces Cartilage Pathology

(2009) M. Helen Rajpar et al.   PLoS Genetics

The Basic Science of Articular Cartilage: Structure, Composition, and Function

(2009) Alice J. Sophia Fox et al.   Sports Health-A Multidisciplinary Approach

Involvement of p38 MAPK in regulation of MMP13 mRNA in chondrocytes in response to surviving stress to endoplasmic reticulum

(2008) Kazunori Hamamura et al.   ARCHIVES OF ORAL BIOLOGY

JNK1-Mediated Phosphorylation of Bcl-2 Regulates Starvation-Induced Autophagy

(2008) Yongjie Wei et al.   MOLECULAR CELL