Eldecalcitol induces apoptosis and autophagy in human osteosarcoma MG-63 cells by accumulating ROS to suppress the PI3K/Akt/mTOR signaling pathway

Matrine triggers colon cancer cell apoptosis and G0/G1 cell cycle arrest via mediation of microRNA‐22

(2020) Jiao Liu et al.   PHYTOTHERAPY RESEARCH

Icariside II suppresses cervical cancer cell migration through JNK modulated matrix metalloproteinase-2/9 inhibition in vitro and in vivo

(2020) Ya-Sai Sun et al.   BIOMEDICINE & PHARMACOTHERAPY

Reactive oxygen species (ROS) as pleiotropic physiological signalling agents

(2020) Helmut Sies et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

LncRNA HOTAIR induces sunitinib resistance in renal cancer by acting as a competing endogenous RNA to regulate autophagy of renal cells

(2020) Dechao Li et al.   Cancer Cell International

pPolyHb protects myocardial H9C2 cells against ischemia-reperfusion injury by regulating the Pink1-Parkin-mediated mitochondrial autophagy pathway

(2019) Wenjin Zhu et al.   Artificial Cells Nanomedicine and Biotechnology

Autophagy-Independent Functions of the Autophagy Machinery

(2019) Lorenzo Galluzzi et al.   CELL

MAT1 facilitates the lung metastasis of osteosarcoma through upregulation of AKT1 expression

(2019) Junjie Wang et al.   LIFE SCIENCES

Icariside II inhibits tumorigenesis via inhibiting AKT/Cyclin E/ CDK 2 pathway and activating mitochondria-dependent pathway

(2019) Ya-Sai Sun et al.   PHARMACOLOGICAL RESEARCH

Apoptosis and Clearance of Apoptotic Cells

(2018) Shigekazu Nagata   Annual Review of Immunology

Taxifolin, a natural flavonoid interacts with cell cycle regulators causes cell cycle arrest and causes tumor regression by activating Wnt/ β -catenin signaling pathway

(2018) Suhail Razak et al.   BMC CANCER

Investigation of the synergistic effects of paclitaxel and herbal substances and endemic plant extracts on cell cycle and apoptosis signal pathways in prostate cancer cell lines

(2018) Zeynep Özlem Doğan Şiğva et al.   GENE

Bcl-2 protects TK6 cells against hydroquinone-induced apoptosis through PARP-1 cytoplasm translocation and stabilizing mitochondrial membrane potential

(2017) Yuting Chen et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Chemotherapy in head and neck osteosarcoma: Adjuvant chemotherapy improves overall survival

(2017) YiMing Chen et al.   ORAL ONCOLOGY

JNK pathway mediates curcumin-induced apoptosis and autophagy in osteosarcoma MG63 cells

(2017) Yaowu Zhang et al.   Experimental and Therapeutic Medicine

The safety and effectiveness profile of eldecalcitol in a prospective, post-marketing observational study in Japanese patients with osteoporosis: interim report

(2016) Hitoshi Saito et al.   JOURNAL OF BONE AND MINERAL METABOLISM

Eldecalcitol (ED-71), an analog of 1α,25-dihydroxyvitamin D3 as a potential anti-cancer agent for oral squamous cell carcinomas

(2016) T. Shintani et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Update on Survival in Osteosarcoma

(2016) Megan E. Anderson   ORTHOPEDIC CLINICS OF NORTH AMERICA

Vitamin D derivatives enhance cytotoxic effects of H 2 O 2 or cisplatin on human keratinocytes

(2016) Anna Piotrowska et al.   STEROIDS

Mechanisms of Autophagy

(2015) Nobuo N. Noda et al.   Annual Review of Biophysics

Osteosarcoma: Current Treatment and a Collaborative Pathway to Success

(2015) Michael S. Isakoff et al.   JOURNAL OF CLINICAL ONCOLOGY

The molecular relationships between apoptosis, autophagy and necroptosis

(2015) Najoua Lalaoui et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma

(2014) Jennifer A. Perry et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular mechanisms of chemoresistance in osteosarcoma (Review)

(2014) HONGTAO HE et al.   Oncology Letters

Modulation of oxidative stress as an anticancer strategy

(2013) Chiara Gorrini et al.   NATURE REVIEWS DRUG DISCOVERY

Autophagosomal Membrane Serves as Platform for Intracellular Death-inducing Signaling Complex (iDISC)-mediated Caspase-8 Activation and Apoptosis

(2012) Megan M. Young et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Classifying collective cancer cell invasion

(2012) Peter Friedl et al.   NATURE CELL BIOLOGY

Autophagic cell death: Loch Ness monster or endangered species?

(2011) Han-Ming Shen et al.   Autophagy

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Synthesis and preliminary biological evaluation of 20-epi-eldecalcitol [20-epi-1α,25-dihydroxy-2β-(3-hydroxypropoxy)vitamin D3: 20-epi-ED-71]

(2010) Susumi Hatakeyama et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Vitamin D, disease and therapeutic opportunities

(2010) Lori A. Plum et al.   NATURE REVIEWS DRUG DISCOVERY

Caspase cleavage of Atg4D stimulates GABARAP-L1 processing and triggers mitochondrial targeting and apoptosis

(2009) V. M. S. Betin et al.   JOURNAL OF CELL SCIENCE

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

(2009) Dunyaporn Trachootham et al.   NATURE REVIEWS DRUG DISCOVERY

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL