CRISPR-Mediated Induction of Neuron-Enriched Mitochondrial Proteins Boosts Direct Glia-to-Neuron Conversion

Effects of Peroxiredoxin 2 in Neurological Disorders: A Review of its Molecular Mechanisms

(2020) Jifei Liu et al.   NEUROCHEMICAL RESEARCH

tRNA Metabolism and Neurodevelopmental Disorders

(2019) Ashleigh E. Schaffer et al.   Annual Review of Genomics and Human Genetics

Dynamic PGAM5 multimers dephosphorylate BCL-xL or FUNDC1 to regulate mitochondrial and cellular fate

(2019) Kaili Ma et al.   CELL DEATH AND DIFFERENTIATION

Direct Lineage Reprogramming for Brain Repair: Breakthroughs and Challenges

(2019) Rory Vignoles et al.   TRENDS IN MOLECULAR MEDICINE

Cell-type-specific profiling of brain mitochondria reveals functional and molecular diversity

(2019) Caroline Fecher et al.   NATURE NEUROSCIENCE

The multifaceted contributions of mitochondria to cellular metabolism

(2018) Jessica B. Spinelli et al.   NATURE CELL BIOLOGY

Proteome-wide identification of ubiquitin interactions using UbIA-MS

(2018) Xiaofei Zhang et al.   Nature Protocols

One step generation of customizable gRNA vectors for multiplex CRISPR approaches through string assembly gRNA cloning (STAgR)

(2018) Christopher T. Breunig et al.   PLoS One

The CPT1a inhibitor, etomoxir induces severe oxidative stress at commonly used concentrations

(2018) Roddy S. O’Connor et al.   Scientific Reports

New approaches for brain repair—from rescue to reprogramming

(2018) Roger A. Barker et al.   NATURE

Astrocyte lipid metabolism is critical for synapse development and function in vivo

(2017) Anne-Lieke F. van Deijk et al.   GLIA

Developmental regulation and localization of carnitine palmitoyltransferases (CPTs) in rat brain

(2017) Jennifer N. Jernberg et al.   JOURNAL OF NEUROCHEMISTRY

Mitostasis in Neurons: Maintaining Mitochondria in an Extended Cellular Architecture

(2017) Thomas Misgeld et al.   NEURON

Inhibition of the Mitochondrial Glutamate Carrier SLC25A22 in Astrocytes Leads to Intracellular Glutamate Accumulation

(2017) Emmanuelle Goubert et al.   Frontiers in Cellular Neuroscience

A Fatty Acid Oxidation-Dependent Metabolic Shift Regulates Adult Neural Stem Cell Activity

(2017) Marlen Knobloch et al.   Cell Reports

Cellular Metabolism and Induced Pluripotency

(2016) Jun Wu et al.   CELL

Mitochondrial Dynamics Impacts Stem Cell Identity and Fate Decisions by Regulating a Nuclear Transcriptional Program

(2016) Mireille Khacho et al.   Cell Stem Cell

Identification and Successful Negotiation of a Metabolic Checkpoint in Direct Neuronal Reprogramming

(2016) Sergio Gascón et al.   Cell Stem Cell

Mutant SOD1 mediated pathogenesis of Amyotrophic Lateral Sclerosis

(2016) Simran J. Kaur et al.   GENE

Mitochondrial Protein PGAM5 Regulates Mitophagic Protection against Cell Necroptosis

(2016) Wei Lu et al.   PLoS One

Transcriptional Mechanisms of Proneural Factors and REST in Regulating Neuronal Reprogramming of Astrocytes

(2015) Giacomo Masserdotti et al.   Cell Stem Cell

Single-Cell Transcriptomics Reveals a Population of Dormant Neural Stem Cells that Become Activated upon Brain Injury

(2015) Enric Llorens-Bobadilla et al.   Cell Stem Cell

Reactive astrocytes as neural stem or progenitor cells: In vivo lineage, In vitro potential, and Genome-wide expression analysis

(2015) Magdalena Götz et al.   GLIA

Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex

(2015) Silvana Konermann et al.   NATURE

Highly efficient Cas9-mediated transcriptional programming

(2015) Alejandro Chavez et al.   NATURE METHODS

MitoCarta2.0: an updated inventory of mammalian mitochondrial proteins

(2015) Sarah E. Calvo et al.   NUCLEIC ACIDS RESEARCH

Two siblings with early infantile myoclonic encephalopathy due to mutation in the gene encoding mitochondrial glutamate/H+ symporter SLC25A22

(2014) Rony Cohen et al.   EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY

Neuronal morphometry directly from bitmap images

(2014) Tiago A Ferreira et al.   NATURE METHODS

Genetic deficiency of the mitochondrial protein PGAM5 causes a Parkinson’s-like movement disorder

(2014) Wei Lu et al.   Nature Communications

A semi-automated method for isolating functionally intact mitochondria from cultured cells and tissue biopsies

(2013) Sabine Schmitt et al.   ANALYTICAL BIOCHEMISTRY

SLC25A22is a novel gene for migrating partial seizures in infancy

(2013) Annapurna Poduri et al.   ANNALS OF NEUROLOGY

GLS2 is transcriptionally regulated by p73 and contributes to neuronal differentiation

(2013) Tania Velletri et al.   CELL CYCLE

Inflammation-Induced Alteration of Astrocyte Mitochondrial Dynamics Requires Autophagy for Mitochondrial Network Maintenance

(2013) Elisa Motori et al.   Cell Metabolism

Functional dissection of the paired domain of Pax6 reveals molecular mechanisms of coordinating neurogenesis and proliferation

(2013) T. Walcher et al.   DEVELOPMENT

Hereditary cataract of the Nakano mouse: Involvement of a hypomorphic mutation in the coproporphyrinogen oxidase gene

(2013) Masayuki Mori et al.   EXPERIMENTAL EYE RESEARCH

Acetylation Stabilizes ATP-Citrate Lyase to Promote Lipid Biosynthesis and Tumor Growth

(2013) Ruiting Lin et al.   MOLECULAR CELL

Metabolic Plasticity in Stem Cell Homeostasis and Differentiation

(2012) Clifford D.L. Folmes et al.   Cell Stem Cell

Regulated temporal-spatial astrocyte precursor cell proliferation involves BRAF signalling in mammalian spinal cord

(2012) A.-C. Tien et al.   DEVELOPMENT

Synaptic Energy Use and Supply

(2012) Julia J. Harris et al.   NEURON

Continuous live imaging of adult neural stem cell division and lineage progression in vitro

(2011) M. R. Costa et al.   DEVELOPMENT

Generation of subtype-specific neurons from postnatal astroglia of the mouse cerebral cortex

(2011) Christophe Heinrich et al.   Nature Protocols

The Mitochondrial Proteome and Human Disease

(2010) Sarah E. Calvo et al.   Annual Review of Genomics and Human Genetics

Peroxiredoxin 6: A Bifunctional Enzyme with Glutathione Peroxidase and Phospholipase A2 Activities

(2010) Aron B. Fisher   ANTIOXIDANTS & REDOX SIGNALING

Direct dynamin–actin interactions regulate the actin cytoskeleton

(2010) Changkyu Gu et al.   EMBO JOURNAL

Directing Astroglia from the Cerebral Cortex into Subtype Specific Functional Neurons

(2010) Christophe Heinrich et al.   PLOS BIOLOGY

Mutations in the mitochondrial glutamate carrierSLC25A22in neonatal epileptic encephalopathy with suppression bursts

(2009) F Molinari et al.   CLINICAL GENETICS

The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C–Cdh1

(2009) Angel Herrero-Mendez et al.   NATURE CELL BIOLOGY

Universal sample preparation method for proteome analysis

(2009) Jacek R Wiśniewski et al.   NATURE METHODS

New insights into brain glutaminases: Beyond their role on glutamatergic transmission

(2009) Javier Márquez et al.   NEUROCHEMISTRY INTERNATIONAL

Electrophoretic Analysis of the Mitochondrial Outer Membrane Rupture Induced by Permeability Transition

(2008) Hans Zischka et al.   ANALYTICAL CHEMISTRY

A Mitochondrial Protein Compendium Elucidates Complex I Disease Biology

(2008) David J. Pagliarini et al.   CELL