Metabolic adaptation to hypoxia: do worms and cancer cells share common metabolic responses to hypoxic stress?

PQM-1 controls hypoxic survival via regulation of lipid metabolism

(2020) Thomas Heimbucher et al.   Nature Communications

Role of mTOR in Glucose and Lipid Metabolism

(2018) Zhuo Mao et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Fructose-driven glycolysis supports anoxia resistance in the naked mole-rat

(2017) Thomas J. Park et al.   SCIENCE

A microRNA program in theC. eleganshypodermis couples to intestinal mTORC2/PQM-1 signaling to modulate fat transport

(2016) Robert H. Dowen et al.   GENES & DEVELOPMENT

Global Profiling of Metabolic Adaptation to Hypoxic Stress in Human Glioblastoma Cells

(2015) Paulina Kucharzewska et al.   PLoS One

MiR-525-3p Enhances the Migration and Invasion of Liver Cancer Cells by Downregulating ZNF395

(2014) Fei Pang et al.   PLoS One

Dysregulated mTORC1 renders cells critically dependent on desaturated lipids for survival under tumor-like stress

(2013) R. M. Young et al.   GENES & DEVELOPMENT

The Hypoxia-Inducible Transcription Factor ZNF395 Is Controlled by IĸB Kinase-Signaling and Activates Genes Involved in the Innate Immune Response and Cancer

(2013) Darko Jordanovski et al.   PLoS One

Hypoxia Promotes Glycogen Accumulation through Hypoxia Inducible Factor (HIF)-Mediated Induction of Glycogen Synthase 1

(2010) Nuria Pescador et al.   PLoS One

The anti-necrosis role of hypoxic preconditioning after acute anoxia is mediated by aldose reductase and sorbitol pathway in PC12 cells

(2009) Li-Ying Wu et al.   CELL STRESS & CHAPERONES

Adaptive Sugar Provisioning Controls Survival of C. elegans Embryos in Adverse Environments

(2009) Harold N. Frazier et al.   CURRENT BIOLOGY