NLRP3 and NLRP1 inflammasomes are up-regulated in patients with mesial temporal lobe epilepsy and may contribute to overexpression of caspase-1 and IL-β in sclerotic hippocampi

Decreased expression of Rev-Erbα in the epileptic foci of temporal lobe epilepsy and activation of Rev-Erbα have anti-inflammatory and neuroprotective effects in the pilocarpine model

(2020) Jiong Yue et al.   Journal of Neuroinflammation

Huperzine A ameliorates cognitive dysfunction and neuroinflammation in kainic acid-induced epileptic rats by antioxidant activity and NLRP3/caspase-1 pathway inhibition

(2019) Parvaneh Mohseni-Moghaddam et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Bcl‐2/Bax ratio increase does not prevent apoptosis of glia and granular neurons in patients with temporal lobe epilepsy

(2019) Eliana C. de Brito Toscano et al.   NEUROPATHOLOGY

Is Targeting the Inflammasome a Way Forward for Neuroscience Drug Discovery?

(2018) Tessa Swanton et al.   SLAS Discovery

Microglial phenotypes in the human epileptic temporal lobe

(2018) Mélanie Morin-Brureau et al.   BRAIN

Curcumin Reduces Neuronal Loss and Inhibits the NLRP3 Inflammasome Activation in an Epileptic Rat Model

(2018) Qianchao He et al.   CURRENT NEUROVASCULAR RESEARCH

Circulating levels of adipokines are altered in patients with temporal lobe epilepsy

(2018) Eliana Cristina de Brito Toscano et al.   EPILEPSY & BEHAVIOR

Brain expression of inflammatory mediators in Mesial Temporal Lobe Epilepsy patients

(2017) Bárbara Leal et al.   JOURNAL OF NEUROIMMUNOLOGY

Biomarkers of Epileptogenesis: The Focus on Glia and Cognitive Dysfunctions

(2017) Annamaria Vezzani et al.   NEUROCHEMICAL RESEARCH

Peripheral leukocyte profile in people with temporal lobe epilepsy reflects the associated proinflammatory state

(2016) Érica Leandro Marciano Vieira et al.   BRAIN BEHAVIOR AND IMMUNITY

Inflammasomes link vascular disease with neuroinflammation and brain disorders

(2016) Nikolett Lénárt et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Dopamine Controls Systemic Inflammation through Inhibition of NLRP3 Inflammasome

(2015) Yiqing Yan et al.   CELL

Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion

(2015) Wan-ting He et al.   CELL RESEARCH

NLRP1 inflammasome is activated in patients with medial temporal lobe epilepsy and contributes to neuronal pyroptosis in amygdala kindling-induced rat model

(2015) Chen-Chen Tan et al.   Journal of Neuroinflammation

GABA A currents are decreased by IL-1β in epileptogenic tissue of patients with temporal lobe epilepsy: implications for ictogenesis

(2015) Cristina Roseti et al.   NEUROBIOLOGY OF DISEASE

IL-1β, IL-6 and IL1Ra levels in temporal lobe epilepsy

(2015) Irem Fatma Uludag et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

NLRP3Inflammasome Polymorphism and Macrovascular Complications in Type 2 Diabetes Patients

(2015) Jasna Klen et al.   Journal of Diabetes Research

Inhibition of the NLRP3 inflammasome provides neuroprotection in rats following amygdala kindling-induced status epilepticus

(2014) Xiang-Fei Meng et al.   Journal of Neuroinflammation

Canonical Nlrp3 Inflammasome Links Systemic Low-Grade Inflammation to Functional Decline in Aging

(2013) Yun-Hee Youm et al.   Cell Metabolism

International consensus classification of hippocampal sclerosis in temporal lobe epilepsy: A Task Force report from the ILAE Commission on Diagnostic Methods

(2013) Ingmar Blümcke et al.   EPILEPSIA

Glia and epilepsy: excitability and inflammation

(2013) Orrin Devinsky et al.   TRENDS IN NEUROSCIENCES

NLRP1 Inflammasome Activation Induces Pyroptosis of Hematopoietic Progenitor Cells

(2012) Seth L. Masters et al.   IMMUNITY

Insights into inflammation and epilepsy from the basic and clinical sciences

(2012) Gustavo Silveira et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Epilepsy and brain inflammation

(2011) Annamaria Vezzani et al.   EXPERIMENTAL NEUROLOGY

Cytokines and epilepsy

(2011) Gang Li et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Interictal alterations of cytokines and leukocytes in patients with active epilepsy

(2010) Mareike Nowak et al.   BRAIN BEHAVIOR AND IMMUNITY

Why mesial temporal lobe epilepsy with hippocampal sclerosis is progressive: Uncontrolled inflammation drives disease progression?

(2010) Tianhua Yang et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Etiology and site of temporal lobe epilepsy influence postictal cytokine release

(2009) Sebastian Bauer et al.   EPILEPSY RESEARCH

Do cytokines have any role in epilepsy?

(2008) S. Sinha et al.   EPILEPSY RESEARCH

NK and CD4+ T cell changes in blood after seizures in temporal lobe epilepsy

(2008) Sebastian Bauer et al.   EXPERIMENTAL NEUROLOGY

Innate and adaptive immunity during epileptogenesis and spontaneous seizures: Evidence from experimental models and human temporal lobe epilepsy

(2007) Teresa Ravizza et al.   NEUROBIOLOGY OF DISEASE