Agomelatine effects on fat-enriched diet induced neuroinflammation and depression-like behavior in rats

Western diet regulates immune status and the response to LPS-driven sepsis independent of diet-associated microbiome

(2019) Brooke A. Napier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Efficacy of anti‐inflammatory treatment on major depressive disorder or depressive symptoms: meta‐analysis of clinical trials

(2019) O. Köhler‐Forsberg et al.   ACTA PSYCHIATRICA SCANDINAVICA

Paricalcitol alleviates lipopolysaccharide-induced depressive-like behavior by suppressing hypothalamic microglia activation and neuroinflammation

(2019) Ming-chao He et al.   BIOCHEMICAL PHARMACOLOGY

Association of high-fat diet with neuroinflammation, anxiety-like defensive behavioral responses, and altered thermoregulatory responses in male rats

(2019) S.S.R. Noronha et al.   BRAIN BEHAVIOR AND IMMUNITY

Higher BDNF plasma levels are associated with a normalization of memory dysfunctions during an antidepressant treatment

(2019) Jan Engelmann et al.   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

Markers of central inflammation in major depressive disorder: A systematic review and meta-analysis of studies examining cerebrospinal fluid, positron emission tomography and post-mortem brain tissue

(2019) Daniela Enache et al.   BRAIN BEHAVIOR AND IMMUNITY

Maternal deprivation increases microglial activation and neuroinflammatory markers in the prefrontal cortex and hippocampus of infant rats

(2019) Vijayasree V. Giridharan et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Melatonin prevents memory impairment induced by high-fat diet: Role of oxidative stress

(2018) Karem H. Alzoubi et al.   BEHAVIOURAL BRAIN RESEARCH

Agave fructans and oligofructose decrease oxidative stress in brain regions involved in learning and memory of overweight mice

(2018) Elena Franco-Robles et al.   NATURAL PRODUCT RESEARCH

Repeated social defeat-induced neuroinflammation, anxiety-like behavior and resistance to fear extinction were attenuated by the cannabinoid receptor agonist WIN55,212-2

(2018) Sabrina Francesca Lisboa et al.   NEUROPSYCHOPHARMACOLOGY

Agomelatine-induced modulation of brain-derived neurotrophic factor (BDNF) in the rat hippocampus

(2018) Yanxia Lu et al.   LIFE SCIENCES

Redox Balance, Antioxidant Defense, and Oxidative Damage in the Hypothalamus and Cerebral Cortex of Rats with High Fat Diet-Induced Insulin Resistance

(2018) Mateusz Maciejczyk et al.   Oxidative Medicine and Cellular Longevity

Vitamin D administration, cognitive function, BBB permeability and neuroinflammatory factors in high-fat diet-induced obese rats

(2017) G Hajiluian et al.   INTERNATIONAL JOURNAL OF OBESITY

Early life experience contributes to the developmental programming of depressive-like behaviour, neuroinflammation and oxidative stress

(2017) Gislaine Z. Réus et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Nrf2 Deficiency Exacerbates Obesity-Induced Oxidative Stress, Neurovascular Dysfunction, Blood–Brain Barrier Disruption, Neuroinflammation, Amyloidogenic Gene Expression, and Cognitive Decline in Mice, Mimicking the Aging Phenotype

(2017) Stefano Tarantini et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Neurological consequences of obesity

(2017) Phillipe D O'Brien et al.   LANCET NEUROLOGY

The impact of obesity on neurodegenerative diseases

(2017) Janaína Niero Mazon et al.   LIFE SCIENCES

Obesity as a risk factor for Alzheimer's disease: weighing the evidence

(2017) S. Alford et al.   Obesity Reviews

Behavioral changes in male mice fed a high-fat diet are associated with IL-1β expression in specific brain regions

(2017) Camila P. Almeida-Suhett et al.   PHYSIOLOGY & BEHAVIOR

Dihydromyricetin exerts a rapid antidepressant-like effect in association with enhancement of BDNF expression and inhibition of neuroinflammation

(2017) Zhaoxiang Ren et al.   PSYCHOPHARMACOLOGY

Obesity-Induced Neuroinflammation: Beyond the Hypothalamus

(2017) Owein Guillemot-Legris et al.   TRENDS IN NEUROSCIENCES

Genome-wide analysis of LPS-induced inflammatory response in the rat ventral hippocampus: Modulatory activity of the antidepressant agomelatine

(2017) Andrea Carlo Rossetti et al.   WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY

Repeated daily administration of increasing doses of lipopolysaccharide provides a model of sustained inflammation-induced depressive-like behaviour in mice that is independent of the NLRP3 inflammasome

(2017) Robin A. Wickens et al.   BEHAVIOURAL BRAIN RESEARCH

Effect of agomelatine on adult hippocampus apoptosis and neurogenesis using the stress model of rats

(2016) Atakan Yucel et al.   ACTA HISTOCHEMICA

Voluntary exercise blocks Western diet-induced gene expression of the chemokines CXCL10 and CCL2 in the prefrontal cortex

(2016) Jesse L. Carlin et al.   BRAIN BEHAVIOR AND IMMUNITY

Dietary obesity reversibly induces synaptic stripping by microglia and impairs hippocampal plasticity

(2016) Shuai Hao et al.   BRAIN BEHAVIOR AND IMMUNITY

Agomelatine reduces brain, kidney and liver oxidative stress but increases plasma cytokine production in the rats with chronic mild stress-induced depression

(2016) Arif Demirdaş et al.   METABOLIC BRAIN DISEASE

Chronic high fat feeding increases anxiety-like behaviour and reduces transcript abundance of glucocorticoid signalling genes in the hippocampus of female rats

(2015) Shathveekan Sivanathan et al.   BEHAVIOURAL BRAIN RESEARCH

High-fat diet-induced metabolic disorders impairs 5-HT function and anxiety-like behavior in mice

(2015) Juliane Zemdegs et al.   BRITISH JOURNAL OF PHARMACOLOGY

Antidepressant Effects of TrkB Ligands on Depression-Like Behavior and Dendritic Changes in Mice After Inflammation

(2015) Ji-chun Zhang et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

High-Fat Diet Induced Anxiety and Anhedonia: Impact on Brain Homeostasis and Inflammation

(2015) Sophie Dutheil et al.   NEUROPSYCHOPHARMACOLOGY

Effect of subchronic administration of agomelatine on brain energy metabolism and oxidative stress parameters in rats

(2015) Aline Haas de Mello et al.   PSYCHIATRY AND CLINICAL NEUROSCIENCES

Role of neuroinflammation in the emotional and cognitive alterations displayed by animal models of obesity

(2015) Nathalie Castanon et al.   Frontiers in Neuroscience

Impairment of hippocampal-dependent memory induced by juvenile high-fat diet intake is associated with enhanced hippocampal inflammation in rats

(2014) Chloé Boitard et al.   BRAIN BEHAVIOR AND IMMUNITY

Diet-induced obesity progressively alters cognition, anxiety-like behavior and lipopolysaccharide-induced depressive-like behavior: Focus on brain indoleamine 2,3-dioxygenase activation

(2014) Caroline André et al.   BRAIN BEHAVIOR AND IMMUNITY

Modulation of the inflammatory response in rats chronically treated with the antidepressant agomelatine

(2013) Raffaella Molteni et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Increased Hippocampal Neurogenesis and Accelerated Response to Antidepressants in Mice with Specific Deletion of CREB in the Hippocampus: Role of cAMP Response-Element Modulator  

(2013) B. B. Gundersen et al.   JOURNAL OF NEUROSCIENCE

Effects of a high-fat diet and bamboo extract supplement on anxiety- and depression-like neurobehaviours in mice

(2012) Adeline Del Rosario et al.   BRITISH JOURNAL OF NUTRITION

Synergistic mechanisms involved in the antidepressant effects of agomelatine

(2012) Daniela Tardito et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

A High-Fat Diet Is Associated With Endotoxemia That Originates From the Gut

(2012) Swaroop Pendyala et al.   GASTROENTEROLOGY

Effect of celecoxib add-on treatment on symptoms and serum IL-6 concentrations in patients with major depressive disorder: Randomized double-blind placebo-controlled study

(2012) Seyed-Hesameddin Abbasi et al.   JOURNAL OF AFFECTIVE DISORDERS

Brain CB1 receptor expression following lipopolysaccharide-induced inflammation

(2012) H. Hu et al.   NEUROSCIENCE

Cognitive and Emotional Alterations Are Related to Hippocampal Inflammation in a Mouse Model of Metabolic Syndrome

(2011) Anne-Laure Dinel et al.   PLoS One

High fat diet increases hippocampal oxidative stress and cognitive impairment in aged mice: implications for decreased Nrf2 signaling

(2010) Christopher D. Morrison et al.   JOURNAL OF NEUROCHEMISTRY

A high-fat diet impairs neurogenesis: Involvement of lipid peroxidation and brain-derived neurotrophic factor

(2010) Hee Ra Park et al.   NEUROSCIENCE LETTERS

Synergistic mechanisms in the modulation of the neurotrophin BDNF in the rat prefrontal cortex following acute agomelatine administration

(2010) Raffaella Molteni et al.   WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY

Cognitive impairment following high fat diet consumption is associated with brain inflammation

(2009) Paul J. Pistell et al.   JOURNAL OF NEUROIMMUNOLOGY