Standardized extract of ginger ameliorates liver cancer by reducing proliferation and inducing apoptosis through inhibition oxidative stress/ inflammation pathway

Strong carcinogenic stress response induction of preneoplastic cells positive for GST-P in the rat liver: Physiological mechanism for initiation

(2018) Kimihiko Satoh   LIFE SCIENCES

Protective and therapeutic potential of ginger (Zingiber officinale ) extract and [6]-gingerol in cancer: A comprehensive review

(2018) Rosália Maria Tôrres de Lima et al.   PHYTOTHERAPY RESEARCH

Molecular characterization of the grape seeds extract’s effect against chemically induced liver cancer: In vivo and in vitro analyses

(2018) Alaaeldin Ahmed Hamza et al.   Scientific Reports

Plants of the Genus Zingiber as a Source of Bioactive Phytochemicals: From Tradition to Pharmacy

(2017) Mehdi Sharifi-Rad et al.   MOLECULES

Animal models as a tool in hepatocellular carcinoma research: A Review

(2017) Nuno Paula Santos et al.   TUMOR BIOLOGY

Anticancer Potential of Ginger: Mechanistic and Pharmaceutical Aspects

(2016) Indu Pal Kaur et al.   CURRENT PHARMACEUTICAL DESIGN

Dietary Natural Products for Prevention and Treatment of Liver Cancer

(2016) Yue Zhou et al.   Nutrients

Global burden of cancers attributable to infections in 2012: a synthetic analysis

(2016) Martyn Plummer et al.   Lancet Global Health

Optimization protocol for the extraction of 6-gingerol and 6-shogaol from Zingiber officinale var. rubrum Theilade and improving antioxidant and anticancer activity using response surface methodology

(2015) Ali Ghasemzadeh et al.   BMC Complementary and Alternative Medicine

Diethylnitrosamine (DEN)-induced carcinogenic liver injury in mice

(2015) R Tolba et al.   LABORATORY ANIMALS

Diet-Based Strategies for Cancer Chemoprevention: The Role of Combination Regimens Using Dietary Bioactive Components

(2015) Christina DiMarco-Crook et al.   Annual Review of Food Science and Technology

Ginger and Its Constituents: Role in Prevention and Treatment of Gastrointestinal Cancer

(2015) Sahdeo Prasad et al.   Gastroenterology Research and Practice

Proteasome inhibition mediates p53 reactivation and anti-cancer activity of 6-Gingerol in cervical cancer cells

(2015) Namrata Rastogi et al.   Oncotarget

Anticancer Effect of Ginger Extract against Pancreatic Cancer Cells Mainly through Reactive Oxygen Species-Mediated Autotic Cell Death

(2015) Miho Akimoto et al.   PLoS One

Differential control of growth, apoptotic activity and gene expression in human colon cancer cells by extracts derived from medicinal herbs,Rhazya strictaandZingiber officinaleand their combination

(2014) Ayman I Elkady   WORLD JOURNAL OF GASTROENTEROLOGY

NF- B, an Active Player in Human Cancers

(2014) Y. Xia et al.   Cancer Immunology Research

6-Gingerol Induces Apoptosis through Lysosomal-Mitochondrial Axis in Human Hepatoma G2 Cells

(2012) Guang Yang et al.   PHYTOTHERAPY RESEARCH

Saffron: A potential candidate for a novel anticancer drug against hepatocellular carcinoma

(2011) Amr Amin et al.   HEPATOLOGY

Ginger ingredients inhibit the development of diethylnitrosoamine induced premalignant phenotype in rat chemical hepatocarcinogenesis model

(2010) Mahmoud A. Mansour et al.   BIOFACTORS

Oxidative stress, inflammation, and cancer: How are they linked?

(2010) Simone Reuter et al.   FREE RADICAL BIOLOGY AND MEDICINE

Induction of apoptosis by [6]-gingerol associated with the modulation of p53 and involvement of mitochondrial signaling pathway in B[a]P-induced mouse skin tumorigenesis

(2009) Nidhi Nigam et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Protective effect of ginger extract against bromobenzene-induced hepatotoxicity in male rats

(2009) A.S. El-Sharaky et al.   FOOD AND CHEMICAL TOXICOLOGY

Ginger's (Zingiber officinaleRoscoe) inhibition of rat colonic adenocarcinoma cells proliferation and angiogenesisin vitro

(2009) Amy C. Brown et al.   PHYTOTHERAPY RESEARCH

A 35-day gavage safety assessment of ginger in rats

(2009) Xianglu Rong et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Diethylnitrosamine (DEN) induces irreversible hepatocellular carcinogenesis through overexpression of G1/S-phase regulatory proteins in rat

(2009) Dae-Hun Park et al.   TOXICOLOGY LETTERS

Ginger extract (Zingiber officinale) has anti-cancer and anti-inflammatory effects on ethionine-induced hepatoma rats

(2008) Shafina Hanim Mohd Habib et al.   Clinics

Myeloperoxidase: A New Biomarker of Inflammation in Ischemic Heart Disease and Acute Coronary Syndromes

(2008) Valentina Loria et al.   MEDIATORS OF INFLAMMATION

Dose translation from animal to human studies revisited

(2007) Shannon Reagan-Shaw et al.   FASEB JOURNAL

Some phytochemical, pharmacological and toxicological properties of ginger (Zingiber officinale Roscoe): A review of recent research

(2007) Badreldin H. Ali et al.   FOOD AND CHEMICAL TOXICOLOGY

Multiple mechanisms are involved in 6-gingerol-induced cell growth arrest and apoptosis in human colorectal cancer cells

(2007) Seong-Ho Lee et al.   MOLECULAR CARCINOGENESIS

The current state of serum biomarkers of hepatotoxicity

(2007) Josef Ozer et al.   TOXICOLOGY