Cargo-free immunomodulatory nanoparticles combined with anti-PD-1 antibody for treating metastatic breast cancer

Intravenous Immunomodulatory Nanoparticle Treatment for Traumatic Brain Injury

(2020) Sripadh Sharma et al.   ANNALS OF NEUROLOGY

Targeting of immunosuppressive myeloid cells from glioblastoma patients by modulation of size and surface charge of lipid nanocapsules

(2020) Laura Pinton et al.   JOURNAL OF NANOBIOTECHNOLOGY

Immunogenomic identification and characterization of granulocytic myeloid derived suppressor cells in multiple myeloma

(2020) Cristina Perez et al.   BLOOD

Autocrine IL6-Mediated Activation of the STAT3–DNMT Axis Silences the TNFα–RIP1 Necroptosis Pathway to Sustain Survival and Accumulation of Myeloid-Derived Suppressor Cells

(2020) Alyssa D. Smith et al.   CANCER RESEARCH

Human tumor-associated monocytes/macrophages and their regulation of T cell responses in early-stage lung cancer

(2019) Sunil Singhal et al.   Science Translational Medicine

Designing drug-free biodegradable nanoparticles to modulate inflammatory monocytes and neutrophils for ameliorating inflammation

(2019) Eiji Saito et al.   JOURNAL OF CONTROLLED RELEASE

Intravascular innate immune cells reprogrammed via intravenous nanoparticles to promote functional recovery after spinal cord injury

(2019) Jonghyuck Park et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immuno-PET identifies the myeloid compartment as a key contributor to the outcome of the antitumor response under PD-1 blockade

(2019) Mohammad Rashidian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cargo-less nanoparticles program innate immune cell responses to toll-like receptor activation

(2019) Liam M. Casey et al.   BIOMATERIALS

Metastatic conditioning of myeloid cells at a subcutaneous synthetic niche reflects disease progression and predicts therapeutic outcomes

(2019) Robert S Oakes et al.   CANCER RESEARCH

Myeloid-driven mechanisms as barriers to antitumor CD8+ T cell activity

(2019) Sean H. Colligan et al.   MOLECULAR IMMUNOLOGY

Multifunctional nanoparticles for cancer immunotherapy: A groundbreaking approach for reprogramming malfunctioned tumor environment

(2018) Samaresh Sau et al.   JOURNAL OF CONTROLLED RELEASE

Neutrophils and PMN-MDSC: Their biological role and interaction with stromal cells

(2018) Jie Zhou et al.   SEMINARS IN IMMUNOLOGY

Cancer Theranostics: Myeloid-Derived Suppressor Cell Membrane-Coated Magnetic Nanoparticles for Cancer Theranostics by Inducing Macrophage Polarization and Synergizing Immunogenic Cell Death (Adv. Funct. Mater. 37/2018)

(2018) Guang-Tao Yu et al.   ADVANCED FUNCTIONAL MATERIALS

Nanomaterials for modulating innate immune cells in cancer immunotherapy

(2018) Quoc-Viet Le et al.   Asian Journal of Pharmaceutical Sciences

Heavy-tailed prior distributions for sequence count data: removing the noise and preserving large differences

(2018) Anqi Zhu et al.   BIOINFORMATICS

Surface Charge-Dependent Cellular Uptake of Polystyrene Nanoparticles

(2018) Soyeon Jeon et al.   Nanomaterials

Repolarization of myeloid derived suppressor cells via magnetic nanoparticles to promote radiotherapy for glioma treatment

(2018) Congyu Wu et al.   Nanomedicine-Nanotechnology Biology and Medicine

Myeloid-Derived Suppressor Cells

(2017) Dmitry I. Gabrilovich   Cancer Immunology Research

Characteristics and Significance of the Pre-metastatic Niche

(2016) Yang Liu et al.   CANCER CELL

Enhanced Survival with Implantable Scaffolds That Capture Metastatic Breast Cancer Cells In Vivo

(2016) Shreyas S. Rao et al.   CANCER RESEARCH

Myeloid-derived suppressor cells as effectors of immune suppression in cancer

(2016) Athalia Rachel Pyzer et al.   INTERNATIONAL JOURNAL OF CANCER

Biodegradable antigen-associated PLG nanoparticles tolerize Th2-mediated allergic airway inflammation pre- and postsensitization

(2016) Charles B. Smarr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circulating Myeloid-Derived Suppressor Cells Predict Differentiated Thyroid Cancer Diagnosis and Extent

(2016) Trevor E. Angell et al.   THYROID

Current understanding of interactions between nanoparticles and the immune system

(2016) Marina A. Dobrovolskaia et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards

(2016) Vincenzo Bronte et al.   Nature Communications

Tumour-educated circulating monocytes are powerful candidate biomarkers for diagnosis and disease follow-up of colorectal cancer

(2015) Alexander Hamm et al.   GUT

Size- and shape-dependent foreign body immune response to materials implanted in rodents and non-human primates

(2015) Omid Veiseh et al.   NATURE MATERIALS

Differential roles of RIPK1 and RIPK3 in TNF-induced necroptosis and chemotherapeutic agent-induced cell death

(2015) K Moriwaki et al.   Cell Death & Disease

Interleukin 33 in tumor microenvironment is crucial for the accumulation and function of myeloid-derived suppressor cells

(2015) Peng Xiao et al.   OncoImmunology

A Biodegradable Nanoparticle Platform for the Induction of Antigen-Specific Immune Tolerance for Treatment of Autoimmune Disease

(2014) Zoe Hunter et al.   ACS Nano

Cessation of CCL2 inhibition accelerates breast cancer metastasis by promoting angiogenesis

(2014) Laura Bonapace et al.   NATURE

Selective uptake of single-walled carbon nanotubes by circulating monocytes for enhanced tumour delivery

(2014) Bryan Ronain Smith et al.   Nature Nanotechnology

Eradication of metastatic mouse cancers resistant to immune checkpoint blockade by suppression of myeloid-derived cells

(2014) K. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Therapeutic Inflammatory Monocyte Modulation Using Immune-Modifying Microparticles

(2014) D. R. Getts et al.   Science Translational Medicine

CSF1R inhibition delays cervical and mammary tumor growth in murine models by attenuating the turnover of tumor-associated macrophages and enhancing infiltration by CD8+T cells

(2014) Debbie C Strachan et al.   OncoImmunology

Immunogenicity of Murine Solid Tumor Models as a Defining Feature of In Vivo Behavior and Response to Immunotherapy

(2013) Melissa G. Lechner et al.   JOURNAL OF IMMUNOTHERAPY

Recruitment of monocytes/macrophages by tissue factor-mediated coagulation is essential for metastatic cell survival and premetastatic niche establishment in mice

(2012) A. M. Gil-Bernabe et al.   BLOOD

Primary Tumor Hypoxia Recruits CD11b+/Ly6Cmed/Ly6G+Immune Suppressor Cells and Compromises NK Cell Cytotoxicity in the Premetastatic Niche

(2012) Jaclyn Sceneay et al.   CANCER RESEARCH

Intermediate Monocytes but Not TIE2-Expressing Monocytes Are a Sensitive Diagnostic Indicator for Colorectal Cancer

(2012) Dominic Schauer et al.   PLoS One

Myeloid Suppressor Cell Depletion Augments Antitumor Activity in Lung Cancer

(2012) Minu K. Srivastava et al.   PLoS One

Selective Effects of PD-1 on Akt and Ras Pathways Regulate Molecular Components of the Cell Cycle and Inhibit T Cell Proliferation

(2012) N. Patsoukis et al.   Science Signaling

CD16+ monocytes in breast cancer patients: expanded by monocyte chemoattractant protein-1 and may be useful for early diagnosis

(2011) A.-L. Feng et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis

(2011) Bin-Zhi Qian et al.   NATURE

Activation of Neutrophils by Nanoparticles

(2011) David M. Goncalves et al.   TheScientificWorldJOURNAL

Different Tumor Microenvironments Contain Functionally Distinct Subsets of Macrophages Derived from Ly6C(high) Monocytes

(2010) K. Movahedi et al.   CANCER RESEARCH

Tumor-associated macrophages in breast cancer as potential biomarkers for new treatments and diagnostics

(2010) Rita A Mukhtar et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Characterization of Cytokine-Induced Myeloid-Derived Suppressor Cells from Normal Human Peripheral Blood Mononuclear Cells

(2010) M. G. Lechner et al.   JOURNAL OF IMMUNOLOGY

A Distinct Macrophage Population Mediates Metastatic Breast Cancer Cell Extravasation, Establishment and Growth

(2009) Binzhi Qian et al.   PLoS One

Chemokine-mediated rapid turnover of myeloid-derived suppressor cells in tumor-bearing mice

(2008) Y. Sawanobori et al.   BLOOD