Identification of novel neurocircuitry through which leptin targets multiple inputs to the dopamine system to reduce food reward seeking

Activation of a lateral hypothalamic-ventral tegmental circuit gates motivation

(2019) Felipe L. Schiffino et al.   PLoS One

Enhancing excitability of dopamine neurons promotes motivational behaviour through increased action initiation

(2018) Linde Boekhoudt et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Relative contributions and mapping of ventral tegmental area dopamine and GABA neurons by projection target in the rat

(2018) Jocelyn M. Breton et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Obesity Pathogenesis: An Endocrine Society Scientific Statement

(2017) Michael W Schwartz et al.   ENDOCRINE REVIEWS

Leptin Substitution in Patients With Lipodystrophy: Neural Correlates for Long-term Success in the Normalization of Eating Behavior

(2016) Haiko Schlögl et al.   DIABETES

Chemogenetic activation of dopamine neurons in the ventral tegmental area, but not substantia nigra, induces hyperactivity in rats

(2016) Linde Boekhoudt et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

The long road to leptin

(2016) Jeffrey Friedman   JOURNAL OF CLINICAL INVESTIGATION

Feeding and Reward Are Differentially Induced by Activating GABAergic Lateral Hypothalamic Projections to VTA

(2016) M. F. Barbano et al.   JOURNAL OF NEUROSCIENCE

Nucleus accumbens D2R cells signal prior outcomes and control risky decision-making

(2016) Kelly A. Zalocusky et al.   NATURE

Inhibitory Input from the Lateral Hypothalamus to the Ventral Tegmental Area Disinhibits Dopamine Neurons and Promotes Behavioral Activation

(2016) Edward H. Nieh et al.   NEURON

Melanocortin 3 Receptor Signaling in Midbrain Dopamine Neurons Increases the Motivation for Food Reward

(2016) Rahul Pandit et al.   NEUROPSYCHOPHARMACOLOGY

Decoding Neural Circuits that Control Compulsive Sucrose Seeking

(2015) Edward H. Nieh et al.   CELL

Visualizing Hypothalamic Network Dynamics for Appetitive and Consummatory Behaviors

(2015) Joshua H. Jennings et al.   CELL

Modulation of cue-induced firing of ventral tegmental area dopamine neurons by leptin and ghrelin

(2015) G van der Plasse et al.   INTERNATIONAL JOURNAL OF OBESITY

Leptin modulates nutrient reward via inhibitory galanin action on orexin neurons

(2015) Amanda Laque et al.   Molecular Metabolism

Combined Use of the Canine Adenovirus-2 and DREADD-Technology to Activate Specific Neural Pathways In Vivo

(2014) Arjen J. Boender et al.   PLoS One

Leptin Action via Neurotensin Neurons Controls Orexin, the Mesolimbic Dopamine System and Energy Balance

(2011) Gina M. Leinninger et al.   Cell Metabolism

Selective deletion of the leptin receptor in dopamine neurons produces anxiogenic-like behavior and increases dopaminergic activity in amygdala

(2011) J Liu et al.   MOLECULAR PSYCHIATRY

Leptin regulates the reward value of nutrient

(2011) Ana I Domingos et al.   NATURE NEUROSCIENCE

Leptin Regulates Energy Balance and Motivation Through Action at Distinct Neural Circuits

(2010) Jon F. Davis et al.   BIOLOGICAL PSYCHIATRY

Ventral Tegmental Area Leptin Receptor Neurons Specifically Project to and Regulate Cocaine- and Amphetamine-Regulated Transcript Neurons of the Extended Central Amygdala

(2010) R. L. Leshan et al.   JOURNAL OF NEUROSCIENCE

Obesity and leptin resistance: distinguishing cause from effect

(2010) Martin G. Myers et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Leptin: a pivotal regulator of human energy homeostasis

(2009) I Sadaf Farooqi et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Leptin Acts via Leptin Receptor-Expressing Lateral Hypothalamic Neurons to Modulate the Mesolimbic Dopamine System and Suppress Feeding

(2009) Gina M. Leinninger et al.   Cell Metabolism

Unique Properties of Mesoprefrontal Neurons within a Dual Mesocorticolimbic Dopamine System

(2008) Stephan Lammel et al.   NEURON