Selective deletion of the leptin receptor in dopamine neurons produces anxiogenic-like behavior and increases dopaminergic activity in amygdala
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Title
Selective deletion of the leptin receptor in dopamine neurons produces anxiogenic-like behavior and increases dopaminergic activity in amygdala
Authors
Keywords
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Journal
MOLECULAR PSYCHIATRY
Volume 16, Issue 10, Pages 1024-1038
Publisher
Springer Nature
Online
2011-04-12
DOI
10.1038/mp.2011.36
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Note: Only part of the references are listed.- Disruption of hypothalamic leptin signaling in mice leads to early-onset obesity, but physiological adaptations in mature animals stabilize adiposity levels
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- Ventral Tegmental Area Leptin Receptor Neurons Specifically Project to and Regulate Cocaine- and Amphetamine-Regulated Transcript Neurons of the Extended Central Amygdala
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- Leptin-deficient mice retain normal appetitive spatial learning yet exhibit marked increases in anxiety-related behaviours
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- Leptin targets in the mouse brain
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- Phasic excitation of dopamine neurons in ventral VTA by noxious stimuli
- (2009) F. Brischoux et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Acute administration of leptin produces anxiolytic-like effects: a comparison with fluoxetine
- (2009) Jing Liu et al. PSYCHOPHARMACOLOGY
- Dopamine receptor gene expression in human amygdaloid nuclei: Elevated D4 receptor mRNA in major depression
- (2008) Lianbin Xiang et al. BRAIN RESEARCH
- Unique Properties of Mesoprefrontal Neurons within a Dual Mesocorticolimbic Dopamine System
- (2008) Stephan Lammel et al. NEURON
- Leptin Replacement Improves Cognitive Development
- (2008) Gilberto J. Paz-Filho et al. PLoS One
- Long-lasting behavioral effects and recognition memory deficit induced by chronic mild stress in mice: effect of antidepressant treatment
- (2008) N. Elizalde et al. PSYCHOPHARMACOLOGY
- The Brain, Appetite, and Obesity
- (2007) Hans-Rudolf Berthoud et al. Annual Review of Psychology
- Collective and Individual Functions of Leptin Receptor Modulated Neurons Controlling Metabolism and Ingestion
- (2007) Esther van de Wall et al. ENDOCRINOLOGY
- Dopaminergic Innervation of the Amygdala Is Highly Responsive to Stress
- (2003) Fiona M. Inglis et al. JOURNAL OF NEUROCHEMISTRY
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