Metformin induced lactic acidosis impaired response of cancer cells towards paclitaxel and doxorubicin: Role of monocarboxylate transporter
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Metformin induced lactic acidosis impaired response of cancer cells towards paclitaxel and doxorubicin: Role of monocarboxylate transporter
Authors
Keywords
Tumor-microenvironment, MCTs, Lactic acidosis, Metabolic reprogramming, Chemotherapeutic outcome, Metformin
Journal
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
Volume 1867, Issue 3, Pages 166011
Publisher
Elsevier BV
Online
2020-11-17
DOI
10.1016/j.bbadis.2020.166011
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Metformin prevention of doxorubicin resistance in MCF-7 and MDA-MB-231 involves oxidative stress generation and modulation of cell adaptation genes
- (2019) Poliana Camila Marinello et al. Scientific Reports
- Tumor stroma interaction is mediated by monocarboxylate metabolism
- (2017) Brijesh B. Patel et al. EXPERIMENTAL CELL RESEARCH
- Metformin synergistically suppress tumor growth with doxorubicin and reverse drug resistance by inhibiting the expression and function of P-glycoprotein in MCF7/ADR cells and xenograft models
- (2017) Ying Li et al. Oncotarget
- Metformin Treatment Does Not Inhibit Growth of Pancreatic Cancer Patient-Derived Xenografts
- (2016) Matthew B. Lipner et al. PLoS One
- MCT4 as a potential therapeutic target for metastatic gastric cancer with peritoneal carcinomatosis
- (2016) Ji Yun Lee et al. Oncotarget
- Histone deacetylase inhibitors regulate P-gp expression in colorectal cancer via transcriptional activation and mRNA stabilization
- (2016) Hao Wang et al. Oncotarget
- Metformin in Cancer Treatment and Prevention
- (2015) Daniel R. Morales et al. Annual Review of Medicine
- Functional screening identifies MCT4 as a key regulator of breast cancer cell metabolism and survival
- (2015) Franziska Baenke et al. JOURNAL OF PATHOLOGY
- Proteasomal inhibition sensitizes cervical cancer cells to mitomycin C-induced bystander effect: the role of tumor microenvironment
- (2015) S V Singh et al. Cell Death & Disease
- Targeting metabolic flexibility by simultaneously inhibiting respiratory complex I and lactate generation retards melanoma progression
- (2015) Balkrishna Chaube et al. Oncotarget
- Strategy to enhance efficacy of doxorubicin in solid tumor cells by methyl-β-cyclodextrin: Involvement of p53 and Fas receptor ligand complex
- (2015) Naoshad Mohammad et al. Scientific Reports
- Obesity induced rapid melanoma progression is reversed by orlistat treatment and dietary intervention: Role of adipokines
- (2014) Parmanand Malvi et al. Molecular Oncology
- The Anti-Diabetic Drug Metformin Protects against Chemotherapy-Induced Peripheral Neuropathy in a Mouse Model
- (2014) Qi-Liang Mao-Ying et al. PLoS One
- MCT4 Defines a Glycolytic Subtype of Pancreatic Cancer with Poor Prognosis and Unique Metabolic Dependencies
- (2014) GuemHee Baek et al. Cell Reports
- Metformin in early breast cancer: a prospective window of opportunity neoadjuvant study
- (2012) Saroj Niraula et al. BREAST CANCER RESEARCH AND TREATMENT
- Metformin and breast cancer risk: a meta-analysis and critical literature review
- (2012) Nananda F. Col et al. BREAST CANCER RESEARCH AND TREATMENT
- Metformin and the Risk of Cancer: Time-related biases in observational studies
- (2012) S. Suissa et al. DIABETES CARE
- Links between metabolism and cancer
- (2012) C. V. Dang GENES & DEVELOPMENT
- Metformin Inhibits Growth of Thyroid Carcinoma Cells, Suppresses Self-Renewal of Derived Cancer Stem Cells, and Potentiates the Effect of Chemotherapeutic Agents
- (2012) Guofang Chen et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Histone Acetylation Regulates Intracellular pH
- (2012) Matthew A. McBrian et al. MOLECULAR CELL
- Cancer Risk in Diabetic Patients Treated with Metformin: A Systematic Review and Meta-analysis
- (2012) Hiroshi Noto et al. PLoS One
- Histone Deacetylase Inhibitors Stimulate Dedifferentiation of Human Breast Cancer Cells Through WNT/β-Catenin Signaling
- (2012) Bisrat G. Debeb et al. STEM CELLS
- Metformin Accelerates the Growth of BRAF V600E -Driven Melanoma by Upregulating VEGF-A
- (2012) Matthew J. Martin et al. Cancer Discovery
- Metformin Decreases the Dose of Chemotherapy for Prolonging Tumor Remission in Mouse Xenografts Involving Multiple Cancer Cell Types
- (2011) D. Iliopoulos et al. CANCER RESEARCH
- Metformin Amplifies Chemotherapy-Induced AMPK Activation and Antitumoral Growth
- (2011) G. Z. Rocha et al. CLINICAL CANCER RESEARCH
- Hyperglycemia regulates MDR-1, drug accumulation and ROS levels causing increased toxicity of carboplatin and 5-fluorouracil in MCF-7 cells
- (2011) Vimal Pandey et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- pH control mechanisms of tumor survival and growth
- (2010) Scott K. Parks et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Warburg effect in chemosensitivity: Targeting lactate dehydrogenase-A re-sensitizes Taxol-resistant cancer cells to Taxol
- (2010) Ming Zhou et al. Molecular Cancer
- Bicarbonate Increases Tumor pH and Inhibits Spontaneous Metastases
- (2009) I. F. Robey et al. CANCER RESEARCH
- Metformin Selectively Targets Cancer Stem Cells, and Acts Together with Chemotherapy to Block Tumor Growth and Prolong Remission
- (2009) H. A. Hirsch et al. CANCER RESEARCH
- Sensors and regulators of intracellular pH
- (2009) Joseph R. Casey et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Causes and Consequences of Increased Glucose Metabolism of Cancers
- (2008) R. J. Gillies et al. JOURNAL OF NUCLEAR MEDICINE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started