Structure and evolution of the bifidobacterial carbohydrate metabolism proteins and enzymes

Cysteine Nucleophiles in Glycosidase Catalysis: Application of a Covalent β‐ l‐ Arabinofuranosidase Inhibitor

(2021) Nicholas G. S. McGregor et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Structural analysis of β‐L‐arabinobiose‐binding protein in the metabolic pathway of hydroxyproline‐rich glycoproteins in Bifidobacterium longum

(2020) Masayuki Miyake et al.   FEBS Journal

Crystal structure of β-L-arabinobiosidase belonging to glycoside hydrolase family 121

(2020) Keita Saito et al.   PLoS One

Insights into the reason of Human-Residential Bifidobacteria (HRB) being the natural inhabitants of the human gut and their potential health-promoting benefits

(2020) Chyn Boon Wong et al.   FEMS MICROBIOLOGY REVIEWS

Butyrate producing colonic Clostridiales metabolise human milk oligosaccharides and cross feed on mucin via conserved pathways

(2020) Michael Jakob Pichler et al.   Nature Communications

Communal living: glycan utilization by the human gut microbiota

(2020) Jonathon A. Briggs et al.   ENVIRONMENTAL MICROBIOLOGY

Molecular evolution and functional divergence of UDP-hexose 4-epimerases

(2020) Shinya Fushinobu   CURRENT OPINION IN CHEMICAL BIOLOGY

Glycan utilization systems in the human gut microbiota: a gold mine for structural discoveries

(2020) Kazune Tamura et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

N-Glycan Utilization by Bifidobacterium Gut Symbionts Involves a Specialist β-Mannosidase

(2019) Rosa Lorizolla Cordeiro et al.   JOURNAL OF MOLECULAR BIOLOGY

Characterization of GH2 and GH42 β-galactosidases derived from bifidobacterial infant isolates

(2019) Valentina Ambrogi et al.   AMB Express

The human gut Firmicute Roseburia intestinalis is a primary degrader of dietary β-mannans

(2019) Sabina Leanti La Rosa et al.   Nature Communications

Two binding proteins of the ABC transporter that confers growth of Bifidobacterium animalis subsp. lactis ATCC27673 on β‐mannan possess distinct manno‐oligosaccharide‐binding profiles

(2019) M. Ejby et al.   MOLECULAR MICROBIOLOGY

Substrate preference of an ABC importer corresponds to selective growth on β-(1,6)-galactosides in Bifidobacterium animalis subsp. lactis

(2019) Mia Christine Theilmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural basis for broad substrate specificity of UDP-glucose 4-epimerase in the human milk oligosaccharide catabolic pathway of Bifidobacterium longum

(2019) Young-Woo Nam et al.   Scientific Reports

Evolutionary adaptation in fucosyllactose uptake systems supports bifidobacteria-infant symbiosis

(2019) Mikiyasu Sakanaka et al.   Science Advances

Bifidobacterium bifidum: A Key Member of the Early Human Gut Microbiota

(2019) Francesca Turroni et al.   Microorganisms

Varied Pathways of Infant Gut-Associated Bifidobacterium to Assimilate Human Milk Oligosaccharides: Prevalence of the Gene Set and Its Correlation with Bifidobacteria-Rich Microbiota Formation

(2019) Mikiyasu Sakanaka et al.   Nutrients

Functional and structural characterization of a β-glucosidase involved in saponin metabolism from intestinal bacteria

(2018) Shan Yan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A Description of Enzymatic Catalysis in N-Acetylhexosamine 1-Kinase: Concerted Mechanism of Two-Magnesium-Ion-Assisted GlcNAc Phosphorylation, Flexibility Behavior of Lid Motif upon Substrate Recognition, and Water-Assisted GlcNAc-1-P Release

(2018) Yuan Zhao et al.   ACS Catalysis

Genomic diversity and distribution of Bifidobacterium longum subsp. longum across the human lifespan

(2018) Toshitaka Odamaki et al.   Scientific Reports

Differential bacterial capture and transport preferences facilitate co-growth on dietary xylan in the human gut

(2018) Maria Louise Leth et al.   Nature Microbiology

Sharing of human milk oligosaccharides degradants within bifidobacterial communities in faecal cultures supplemented with Bifidobacterium bifidum

(2018) Aina Gotoh et al.   Scientific Reports

Unveiling bifidobacterial biogeography across the mammalian branch of the tree of life

(2017) Christian Milani et al.   ISME Journal

Polysaccharide Utilization Loci: Fueling Microbial Communities

(2017) Julie M. Grondin et al.   JOURNAL OF BACTERIOLOGY

Discovery of α-l-arabinopyranosidases from human gut microbiome expands the diversity within glycoside hydrolase family 42

(2017) Alexander Holm Viborg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The first crystal structure of a family 129 glycoside hydrolase from a probiotic bacterium reveals critical residues and metal cofactors

(2017) Mayo Sato et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural basis for nutrient acquisition by dominant members of the human gut microbiota

(2017) Amy J. Glenwright et al.   NATURE

Lactobacillus acidophilus Metabolizes Dietary Plant Glucosides and Externalizes Their Bioactive Phytochemicals

(2017) Mia C. Theilmann et al.   mBio

Host-derived glycans serve as selected nutrients for the gut microbe: human milk oligosaccharides and bifidobacteria

(2016) Takane Katayama   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Crystal structure of β1→6-galactosidase fromBifidobacterium bifidumS17: trimeric architecture, molecular determinants of the enzymatic activity and its inhibition by α-galactose

(2016) Andre Schutzer Godoy et al.   FEBS Journal

An updated structural classification of substrate-binding proteins

(2016) Giel H. Scheepers et al.   FEBS LETTERS

Galactomannan Catabolism Conferred by a Polysaccharide Utilization Locus ofBacteroides ovatus

(2016) Viktoria Bågenholm et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An ATP Binding Cassette Transporter Mediates the Uptake of α-(1,6)-Linked Dietary Oligosaccharides inBifidobacteriumand Correlates with Competitive Growth on These Substrates

(2016) Morten Ejby et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Diet–microbiota interactions as moderators of human metabolism

(2016) Justin L. Sonnenburg et al.   NATURE

Cospeciation of gut microbiota with hominids

(2016) A. H. Moeller et al.   SCIENCE

Crystal structure of a putative exo-β-1,3-galactanase fromBifidobacterium bifidumS17

(2016) Andre S. Godoy et al.   Acta Crystallographica Section F-Structural Biology Communications

Open–close structural change upon ligand binding and two magnesium ions required for the catalysis of N-acetylhexosamine 1-kinase

(2015) Mayo Sato et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

The GH5 1,4-β-mannanase from Bifidobacterium animalis subsp. lactis Bl-04 possesses a low-affinity mannan-binding module and highlights the diversity of mannanolytic enzymes

(2015) Johan Morrill et al.   BMC BIOCHEMISTRY

Structural Analysis of a Family 101 Glycoside Hydrolase in Complex with Carbohydrates Reveals Insights into Its Mechanism

(2015) Katie J. Gregg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glycan complexity dictates microbial resource allocation in the large intestine

(2015) Artur Rogowski et al.   Nature Communications

Mucin glycan foraging in the human gut microbiome

(2015) Louise E. Tailford et al.   Frontiers in Genetics

Crystal structure of glycoside hydrolase family 127 β-l-arabinofuranosidase from Bifidobacterium longum

(2014) Tasuku Ito et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Role of the Microbiota in Immunity and Inflammation

(2014) Yasmine Belkaid et al.   CELL

Characterization of a Novel β-l-Arabinofuranosidase inBifidobacterium longum

(2014) Kiyotaka Fujita et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural diversity of ABC transporters

(2014) Josy ter Beek et al.   JOURNAL OF GENERAL PHYSIOLOGY

A β1-6/β1-3 galactosidase fromBifidobacterium animalissubsp.lactis Bl-04 gives insight into sub-specificities of β-galactoside catabolism withinBifidobacterium

(2014) Alexander Holm Viborg et al.   MOLECULAR MICROBIOLOGY

Insights into the binding specificity and catalytic mechanism ofN-acetylhexosamine 1-phosphate kinases through multiple reaction complexes

(2014) Kuei-Chen Wang et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Unraveling the Leloir Pathway of Bifidobacterium bifidum: Significance of the Uridylyltransferases

(2013) Frederik De Bruyn et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Transcriptional analysis of oligosaccharide utilization by Bifidobacterium lactis Bl-04

(2013) Joakim Mark Andersen et al.   BMC GENOMICS

Lacto-N-biosidase Encoded by a Novel Gene ofBifidobacterium longumSubspecieslongumShows Unique Substrate Specificity and Requires a Designated Chaperone for Its Active Expression

(2013) Haruko Sakurama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structures of a Glycoside Hydrolase Family 20 Lacto-N-biosidase fromBifidobacterium bifidum

(2013) Tasuku Ito et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural basis for arabinoxylo-oligosaccharide capture by the probioticBifidobacterium animalissubsp.lactis Bl-04

(2013) Morten Ejby et al.   MOLECULAR MICROBIOLOGY

The carbohydrate-active enzymes database (CAZy) in 2013

(2013) Vincent Lombard et al.   NUCLEIC ACIDS RESEARCH

Expression and Characterization of a Bifidobacterium adolescentis Beta-Mannanase Carrying Mannan-Binding and Cell Association Motifs

(2012) Evelina Kulcinskaja et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

The Impact of the Gut Microbiota on Human Health: An Integrative View

(2012) Jose C. Clemente et al.   CELL

Enzymology and Structure of the GH13_31 Glucan 1,6- -Glucosidase That Confers Isomaltooligosaccharide Utilization in the Probiotic Lactobacillus acidophilus NCFM

(2012) M. S. Moller et al.   JOURNAL OF BACTERIOLOGY

1,3-1,4-α-l-Fucosynthase That Specifically Introduces Lewis a/x Antigens into Type-1/2 Chains

(2012) Haruko Sakurama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

How glycan metabolism shapes the human gut microbiota

(2012) Nicole M. Koropatkin et al.   NATURE REVIEWS MICROBIOLOGY

Bifidobacterium longum subsp. infantis ATCC 15697 α-Fucosidases Are Active on Fucosylated Human Milk Oligosaccharides

(2011) David A. Sela et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Crystal structures of the apo form of β-fructofuranosidase from Bifidobacterium longum and its complex with fructose

(2011) Anna Bujacz et al.   FEBS Journal

Carbohydrate metabolism in Bifidobacteria

(2011) Karina Pokusaeva et al.   Genes and Nutrition

α-N-Acetylgalactosaminidase from Infant-associated Bifidobacteria Belonging to Novel Glycoside Hydrolase Family 129 Is Implicated in Alternative Mucin Degradation Pathway

(2011) Masashi Kiyohara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structure of α-Galactosidase from Lactobacillus acidophilus NCFM: Insight into Tetramer Formation and Substrate Binding

(2011) Folmer Fredslund et al.   JOURNAL OF MOLECULAR BIOLOGY

Enterotypes of the human gut microbiome

(2011) Manimozhiyan Arumugam et al.   NATURE

Overexpression, crystallization and preliminary X-ray analysis of xylulose-5-phosphate/fructose-6-phosphate phosphoketolase fromBifidobacterium breve

(2010) Ryuichiro Suzuki et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Unique Sugar Metabolic Pathways of Bifidobacteria

(2010) Shinya FUSHINOBU   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Crystal structure ofBifidobacterium Longumphosphoketolase; key enzyme for glucose metabolism inBifidobacterium

(2010) Kazutoshi Takahashi et al.   FEBS LETTERS

Genomics and ecological overview of the genus Bifidobacterium

(2010) Francesca Turroni et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

Molecular Cloning and Characterization of a β-l-Arabinobiosidase inBifidobacterium longumThat Belongs to a Novel Glycoside Hydrolase Family

(2010) Kiyotaka Fujita et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structures of Phosphoketolase

(2010) Ryuichiro Suzuki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nursing our microbiota: molecular linkages between bifidobacteria and milk oligosaccharides

(2010) David A. Sela et al.   TRENDS IN MICROBIOLOGY

Prebiotic Effect of Lacto-N-biose I on Bifidobacterial Growth

(2009) Masashi KIYOHARA et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Crystallographic and Mutational Analyses of Substrate Recognition of Endo-α-N-acetylgalactosaminidase from Bifidobacterium longum

(2009) Ryuichiro Suzuki et al.   JOURNAL OF BIOCHEMISTRY

The Crystal Structure of Galacto-N-biose/Lacto-N-biose I Phosphorylase

(2009) Masafumi Hidaka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bifidobacterium bifidum Lacto-N-Biosidase, a Critical Enzyme for the Degradation of Human Milk Oligosaccharides with a Type 1 Structure

(2008) J. Wada et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Microbes in Gastrointestinal Health and Disease

(2008) Andrew S. Neish   GASTROENTEROLOGY

Structural and Thermodynamic Analyses of Solute-binding Protein fromBifidobacterium longumSpecific for Core 1 Disaccharide and Lacto-N-biose I

(2008) Ryuichiro Suzuki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY