Charge Manipulation Using Solution and Gas-Phase Chemistry to Facilitate Analysis of Highly Heterogeneous Protein Complexes in Native Mass Spectrometry

Enhancing Protein Electrospray Charge States by Multivalent Metal Ions: Mechanistic Insights from MD Simulations and Mass Spectrometry Experiments

(2020) Leanne M. Martin et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

A wealth of genotype-specific proteoforms fine-tunes hemoglobin scavenging by haptoglobin

(2020) Sem Tamara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-Pressure Electrospray Ionization Yields Supercharged Protein Complexes from Native Solutions While Preserving Noncovalent Interactions

(2020) Zhibin Yin et al.   ANALYTICAL CHEMISTRY

Recent Developments in Gas-Phase Ion/Ion Reactions for Analytical Mass Spectrometry

(2019) David J. Foreman et al.   ANALYTICAL CHEMISTRY

Integration of On-Column Chemical Reactions in Protein Characterization by Liquid Chromatography/Mass Spectrometry: Cross-Path Reactive Chromatography

(2018) Jake W. Pawlowski et al.   ANALYTICAL CHEMISTRY

How can native mass spectrometry contribute to characterization of biomacromolecular higher-order structure and interactions?

(2018) Wenjun Tong et al.   METHODS

Ultrasensitive Characterization of Charge Heterogeneity of Therapeutic Monoclonal Antibodies Using Strong Cation Exchange Chromatography Coupled to Native Mass Spectrometry

(2018) Yuetian Yan et al.   ANALYTICAL CHEMISTRY

Mechanism of Protein Supercharging by Sulfolane and m-Nitrobenzyl Alcohol: Molecular Dynamics Simulations of the Electrospray Process

(2016) Haidy Metwally et al.   ANALYTICAL CHEMISTRY

Interactions of Intact Unfractionated Heparin with Its Client Proteins Can Be Probed Directly Using Native Electrospray Ionization Mass Spectrometry

(2016) Yunlong Zhao et al.   ANALYTICAL CHEMISTRY

Interactions of Haptoglobin with Monomeric Globin Species: Insights from Molecular Modeling and Native Electrospray Ionization Mass Spectrometry

(2016) Ololade Fatunmbi et al.   BIOCHEMISTRY

New supercharging reagents produce highly charged protein ions in native mass spectrometry

(2015) Catherine C. Going et al.   ANALYST

Influence of Sulfolane on ESI-MS Measurements of Protein–Ligand Affinities

(2015) Yuyu Yao et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Solution Additives for Supercharging Proteins beyond the Theoretical Maximum Proton-Transfer Limit in Electrospray Ionization Mass Spectrometry

(2014) Chen A. Teo et al.   ANALYTICAL CHEMISTRY

What Protein Charging (and Supercharging) Reveal about the Mechanism of Electrospray Ionization

(2014) Rachel R. Ogorzalek Loo et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Studies of pH-Dependent Self-Association of a Recombinant Form of Arylsulfatase A with Electrospray Ionization Mass Spectrometry and Size-Exclusion Chromatography

(2012) Rinat R. Abzalimov et al.   ANALYTICAL CHEMISTRY

Structure of the haptoglobin–haemoglobin complex

(2012) Christian Brix Folsted Andersen et al.   NATURE

Mass Spectrometric Strategies and Their Applications for Molecular Mass Determination of Recombinant Therapeutic Proteins

(2011) Marina Carini et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Electrospray Ionization Mass Spectrometry of Highly Heterogeneous Protein Systems: Protein Ion Charge State Assignment via Incomplete Charge Reduction

(2010) Rinat R. Abzalimov et al.   ANALYTICAL CHEMISTRY

Effects of supercharging reagents on noncovalent complex structure in electrospray ionization from aqueous solutions

(2010) Harry J. Sterling et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Evolutionary Aspects of Hemoglobin Scavengers

(2009) Krzysztof B. Wicher et al.   ANTIOXIDANTS & REDOX SIGNALING

Characterization of high molecular weight multimeric states of human haptoglobin and hemoglobin-based oxygen carriers by high-mass MALDI MS

(2009) Tatiana Pimenova et al.   JOURNAL OF SEPARATION SCIENCE

Do Ionic Charges in ESI MS Provide Useful Information on Macromolecular Structure?

(2008) I KALTASHOV et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Molecular mass analysis of antibodies by on-line SEC-MS

(2008) Lowell J. Brady et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Increasing charge while preserving noncovalent protein complexes for ESI-MS

(2008) Shirley H. Lomeli et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Evolution of instrumentation for the study of gas-phase ion/ion chemistry via mass spectrometry

(2007) Yu Xia et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY