BiT age: A transcriptome‐based aging clock near the theoretical limit of accuracy

Personal aging markers and ageotypes revealed by deep longitudinal profiling

(2020) Sara Ahadi et al.   NATURE MEDICINE

Biohorology and biomarkers of aging: Current state-of-the-art, challenges and opportunities

(2020) Fedor Galkin et al.   AGEING RESEARCH REVIEWS

A universal transcriptomic signature of age reveals the temporal scaling of Caenorhabditis elegans aging trajectories

(2019) Andrei E. Tarkhov et al.   Scientific Reports

Host-Microbe-Drug-Nutrient Screen Identifies Bacterial Effectors of Metformin Therapy

(2019) Rosina Pryor et al.   CELL

Regulation of lifespan by neural excitation and REST

(2019) Joseph M. Zullo et al.   NATURE

Redirection of SKN-1 abates the negative metabolic outcomes of a perceived pathogen infection

(2019) James D. Nhan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Machine Learning on Human Muscle Transcriptomic Data for Biomarker Discovery and Tissue-Specific Drug Target Identification

(2018) Polina Mamoshina et al.   Frontiers in Genetics

Drug Synergy Slows Aging and Improves Healthspan through IGF and SREBP Lipid Signaling

(2018) Tesfahun Dessale Admasu et al.   DEVELOPMENTAL CELL

Wnt Secretion Is Regulated by the Tetraspan Protein HIC-1 through Its Interaction with Neurabin/NAB-1

(2018) Vina Tikiyani et al.   Cell Reports

Genetic variation in glia–neuron signalling modulates ageing rate

(2017) Jiang-An Yin et al.   NATURE

Indoles from commensal bacteria extend healthspan

(2017) Robert Sonowal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A microRNA feedback loop regulates global microRNA abundance during aging

(2017) Sachi Inukai et al.   RNA

Dual-stimuli responsive and reversibly activatable theranostic nanoprobe for precision tumor-targeting and fluorescence-guided photothermal therapy

(2017) Xu Zhao et al.   Nature Communications

Genome-wide RNAi Screen for Fat Regulatory Genes in C. elegans Identifies a Proteostasis-AMPK Axis Critical for Starvation Survival

(2017) Christopher M. Webster et al.   Cell Reports

Innate immunity mediated longevity and longevity induced by germ cell removal converge on the C-type lectin domain protein IRG-7

(2017) Elad Yunger et al.   PLoS Genetics

Computational Analysis of Lifespan Experiment Reproducibility

(2017) Michael Petrascheck et al.   Frontiers in Genetics

Dopamine signaling promotes the xenobiotic stress response and protein homeostasis

(2016) Kishore K Joshi et al.   EMBO JOURNAL

The temporal scaling of Caenorhabditis elegans ageing

(2016) Nicholas Stroustrup et al.   NATURE

Deactivation of the GATA Transcription Factor ELT-2 Is a Major Driver of Normal Aging in C. elegans

(2016) Frederick G. Mann et al.   PLoS Genetics

Long live FOXO: unraveling the role of FOXO proteins in aging and longevity

(2015) Rute Martins et al.   AGING CELL

Optimization of Codon Translation Rates via tRNA Modifications Maintains Proteome Integrity

(2015) Danny D. Nedialkova et al.   CELL

The transcriptional landscape of age in human peripheral blood

(2015) Marjolein J. Peters et al.   Nature Communications

Suppression of transcriptional drift extends C. elegans lifespan by postponing the onset of mortality

(2015) Sunitha Rangaraju et al.   eLife

Adaptive Capacity to Bacterial Diet Modulates Aging in C. elegans

(2014) Shanshan Pang et al.   Cell Metabolism

Insights from the worm: The C. elegans model for innate immunity

(2014) Maria A. Ermolaeva et al.   SEMINARS IN IMMUNOLOGY

Germline Signals Deploy NHR-49 to Modulate Fatty-Acid β-Oxidation and Desaturation in Somatic Tissues of C. elegans

(2014) Ramesh Ratnappan et al.   PLoS Genetics

PQM-1 Complements DAF-16 as a Key Transcriptional Regulator of DAF-2-Mediated Development and Longevity

(2013) Ronald G. Tepper et al.   CELL

Neuronal ROS signaling rather than AMPK/sirtuin-mediated energy sensing links dietary restriction to lifespan extension

(2013) Sebastian Schmeisser et al.   Molecular Metabolism

Impaired Insulin/IGF1 Signaling Extends Life Span by Promoting Mitochondrial L-Proline Catabolism to Induce a Transient ROS Signal

(2012) Kim Zarse et al.   Cell Metabolism

RPN-6 determines C. elegans longevity under proteotoxic stress conditions

(2012) David Vilchez et al.   NATURE

A Decline in p38 MAPK Signaling Underlies Immunosenescence in Caenorhabditis elegans

(2011) Matthew J. Youngman et al.   PLoS Genetics

Inferring the functions of longevity genes with modular subnetwork biomarkers of Caenorhabditis elegans aging

(2010) Kristen Fortney et al.   GENOME BIOLOGY

Age-related behaviors have distinct transcriptional profiles inCaenorhabditis elegans

(2008) Tamara R. Golden et al.   AGING CELL

An elt-3/elt-5/elt-6 GATA Transcription Circuit Guides Aging in C. elegans

(2008) Yelena V. Budovskaya et al.   CELL