Single-cell analysis supports a luminal-neuroendocrine transdifferentiation in human prostate cancer
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Single-cell analysis supports a luminal-neuroendocrine transdifferentiation in human prostate cancer
Authors
Keywords
-
Journal
Communications Biology
Volume 3, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-12-16
DOI
10.1038/s42003-020-01476-1
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Identification of a Zeb1 expressing basal stem cell subpopulation in the prostate
- (2020) Xue Wang et al. Nature Communications
- An Engineered CRISPR-Cas9 Mouse Line for Simultaneous Readout of Lineage Histories and Gene Expression Profiles in Single Cells
- (2020) Sarah Bowling et al. CELL
- Regenerative potential of prostate luminal cells revealed by single-cell analysis
- (2020) Wouter R. Karthaus et al. SCIENCE
- Neuroendocrine prostate carcinoma cells originate from the p63-expressing basal cells but not the pre-existing adenocarcinoma cells in mice
- (2019) Dong-Kee Lee et al. CELL RESEARCH
- Single-Cell RNA-Seq Reveals AML Hierarchies Relevant to Disease Progression and Immunity
- (2019) Peter van Galen et al. CELL
- Increased Serine and One-Carbon Pathway Metabolism by PKCλ/ι Deficiency Promotes Neuroendocrine Prostate Cancer
- (2019) Miguel Reina-Campos et al. CANCER CELL
- A comparison of single-cell trajectory inference methods
- (2019) Wouter Saelens et al. NATURE BIOTECHNOLOGY
- The role of lineage plasticity in prostate cancer therapy resistance
- (2019) Himisha Beltran et al. CLINICAL CANCER RESEARCH
- Resolving medulloblastoma cellular architecture by single-cell genomics
- (2019) Volker Hovestadt et al. NATURE
- Spatiotemporal structure of cell fate decisions in murine neural crest
- (2019) Ruslan Soldatov et al. SCIENCE
- N-Myc–mediated epigenetic reprogramming drives lineage plasticity in advanced prostate cancer
- (2019) Adeline Berger et al. JOURNAL OF CLINICAL INVESTIGATION
- Molecular profiling stratifies diverse phenotypes of treatment-refractory metastatic castration-resistant prostate cancer
- (2019) Mark P. Labrecque et al. JOURNAL OF CLINICAL INVESTIGATION
- Fast, sensitive and accurate integration of single-cell data with Harmony
- (2019) Ilya Korsunsky et al. NATURE METHODS
- EMT, stemness and tumor plasticity in aggressive variant neuroendocrine prostate cancers
- (2018) Rama Soundararajan et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Cellular plasticity and the neuroendocrine phenotype in prostate cancer
- (2018) Alastair H. Davies et al. Nature Reviews Urology
- Neuroendocrine Differentiation in Prostate Cancer: Emerging Biology, Models, and Therapies
- (2018) Loredana Puca et al. Cold Spring Harbor Perspectives in Medicine
- RNA velocity of single cells
- (2018) Gioele La Manno et al. NATURE
- Reprogramming normal human epithelial tissues to a common, lethal neuroendocrine cancer lineage
- (2018) Jung Wook Park et al. SCIENCE
- Single-Cell Analysis Identifies LY6D as a Marker Linking Castration-Resistant Prostate Luminal Cells to Prostate Progenitors and Cancer
- (2018) João D. Barros-Silva et al. Cell Reports
- A Cellular Anatomy of the Normal Adult Human Prostate and Prostatic Urethra
- (2018) Gervaise H. Henry et al. Cell Reports
- FOXA2 is a sensitive and specific marker for small cell neuroendocrine carcinoma of the prostate
- (2017) Jung Wook Park et al. MODERN PATHOLOGY
- SCENIC: single-cell regulatory network inference and clustering
- (2017) Sara Aibar et al. NATURE METHODS
- SOX2 promotes lineage plasticity and antiandrogen resistance in TP53 - and RB1 -deficient prostate cancer
- (2017) Ping Mu et al. SCIENCE
- In situ click chemistry generation of cyclooxygenase-2 inhibitors
- (2017) Atul Bhardwaj et al. Nature Communications
- Massively parallel digital transcriptional profiling of single cells
- (2017) Grace X. Y. Zheng et al. Nature Communications
- Transdifferentiation as a Mechanism of Treatment Resistance in a Mouse Model of Castration-Resistant Prostate Cancer
- (2017) Min Zou et al. Cancer Discovery
- Lhx2 Expression in Postmitotic Cortical Neurons Initiates Assembly of the Thalamocortical Somatosensory Circuit
- (2017) Chia-Fang Wang et al. Cell Reports
- Comparison of independent screens on differentially vulnerable motor neurons reveals alpha-synuclein as a common modifier in motor neuron diseases
- (2017) Rachel A. Kline et al. PLoS Genetics
- N-Myc Induces an EZH2-Mediated Transcriptional Program Driving Neuroendocrine Prostate Cancer
- (2016) Etienne Dardenne et al. CANCER CELL
- N-Myc Drives Neuroendocrine Prostate Cancer Initiated from Human Prostate Epithelial Cells
- (2016) John K. Lee et al. CANCER CELL
- Treatment-related neuroendocrine prostate cancer resulting in Cushing's syndrome
- (2016) Sundhar Ramalingam et al. INTERNATIONAL JOURNAL OF UROLOGY
- Neuroendocrine Cells of the Prostate Derive from the Neural Crest
- (2016) Jaroslaw Szczyrba et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Divergent clonal evolution of castration-resistant neuroendocrine prostate cancer
- (2016) Himisha Beltran et al. NATURE MEDICINE
- Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq
- (2016) I. Tirosh et al. SCIENCE
- The Master Neural Transcription Factor BRN2 Is an Androgen Receptor–Suppressed Driver of Neuroendocrine Differentiation in Prostate Cancer
- (2016) Jennifer L. Bishop et al. Cancer Discovery
- Establishing neural crest identity: a gene regulatory recipe
- (2015) M. Simoes-Costa et al. DEVELOPMENT
- The Ectoenzyme E-NPP3 Negatively Regulates ATP-Dependent Chronic Allergic Responses by Basophils and Mast Cells
- (2015) Shih Han Tsai et al. IMMUNITY
- A basal stem cell signature identifies aggressive prostate cancer phenotypes
- (2015) Bryan A. Smith et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- RNA-Seq of single prostate CTCs implicates noncanonical Wnt signaling in antiandrogen resistance
- (2015) D. T. Miyamoto et al. SCIENCE
- Organoid Cultures Derived from Patients with Advanced Prostate Cancer
- (2014) Dong Gao et al. CELL
- Aggressive Variants of Castration-Resistant Prostate Cancer
- (2014) H. Beltran et al. CLINICAL CANCER RESEARCH
- Critical Roles for PU.1, GATA1, and GATA2 in the Expression of Human Fc RI on Mast Cells: PU.1 and GATA1 Transactivate FCER1A, and GATA2 Transactivates FCER1A and MS4A2
- (2014) E. Inage et al. JOURNAL OF IMMUNOLOGY
- Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma
- (2014) A. P. Patel et al. SCIENCE
- GSVA: gene set variation analysis for microarray and RNA-Seq data
- (2013) Sonja Hänzelmann et al. BMC BIOINFORMATICS
- Lineage analysis of basal epithelial cells reveals their unexpected plasticity and supports a cell-of-origin model for prostate cancer heterogeneity
- (2013) Zhu A. Wang et al. NATURE CELL BIOLOGY
- Dual role of FoxA1 in androgen receptor binding to chromatin, androgen signalling and prostate cancer
- (2011) Biswajyoti Sahu et al. EMBO JOURNAL
- ERG–TMPRSS2 rearrangement is shared by concurrent prostatic adenocarcinoma and prostatic small cell carcinoma and absent in small cell carcinoma of the urinary bladder: evidence supporting monoclonal origin
- (2011) Sean R Williamson et al. MODERN PATHOLOGY
- Molecular Characterization of Neuroendocrine Prostate Cancer and Identification of New Drug Targets
- (2011) H. Beltran et al. Cancer Discovery
- Siah2-Dependent Concerted Activity of HIF and FoxA2 Regulates Formation of Neuroendocrine Phenotype and Neuroendocrine Prostate Tumors
- (2010) Jianfei Qi et al. CANCER CELL
- TMPRSS2-ERG gene fusion in small cell carcinoma of the prostate☆
- (2010) Charles C. Guo et al. HUMAN PATHOLOGY
- Uncx regulates proliferation of neural progenitor cells and neuronal survival in the olfactory epithelium
- (2010) Neeraja Sammeta et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Identification of a Cell of Origin for Human Prostate Cancer
- (2010) A. S. Goldstein et al. SCIENCE
- Forcing cells to change lineages
- (2009) Thomas Graf et al. NATURE
- Human ASH1 expression in prostate cancer with neuroendocrine differentiation
- (2008) Ida Rapa et al. MODERN PATHOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search