Rapid removal of phagosomal ferroportin in macrophages contributes to nutritional immunity

De novo purine biosynthesis is required for intracellular growth of Staphylococcus aureus and for the hypervirulence phenotype of a purR mutant

(2020) Mariya I. Goncheva et al.   INFECTION AND IMMUNITY

Macrophage‐driven nutrient delivery to phagosomal Staphylococcus aureus supports bacterial growth

(2020) Ronald S Flannagan et al.   EMBO REPORTS

Staphylococcus aureus heme and siderophore-iron acquisition pathways

(2019) Brigid S. Conroy et al.   BIOMETALS

Staphylococcus aureus Uses the GraXRS Regulatory System To Sense and Adapt to the Acidified Phagolysosome in Macrophages

(2018) Ronald S. Flannagan et al.   mBio

The hepcidin-ferroportin axis controls the iron content of Salmonella-containing vacuoles in macrophages

(2018) Daejin Lim et al.   Nature Communications

A Fluorescence Based-Proliferation Assay for the Identification of Replicating Bacteria Within Host Cells

(2018) Ronald S. Flannagan et al.   Frontiers in Microbiology

Identification and treatment of the Staphylococcus aureus reservoir in vivo

(2016) Bas G.J. Surewaard et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Heme Synthesis and Acquisition in Bacterial Pathogens

(2016) Jacob E. Choby et al.   JOURNAL OF MOLECULAR BIOLOGY

A phosphoinositide conversion mechanism for exit from endosomes

(2016) Katharina Ketel et al.   NATURE

Intracellular replication ofStaphylococcus aureusin mature phagolysosomes in macrophages precedes host cell death, and bacterial escape and dissemination

(2015) Ronald S. Flannagan et al.   CELLULAR MICROBIOLOGY

Take the tube: remodelling of the endosomal system by intracellularSalmonella enterica

(2015) Viktoria Liss et al.   CELLULAR MICROBIOLOGY

Contrasting regulation of macrophage iron homeostasis in response to infection with Listeria monocytogenes depending on localization of bacteria

(2015) David Haschka et al.   Metallomics

Phosphoinositide 3-kinase enables phagocytosis of large particles by terminating actin assembly through Rac/Cdc42 GTPase-activating proteins

(2015) Daniel Schlam et al.   Nature Communications

Inverse agonist of estrogen-related receptor γ controls Salmonella typhimurium infection by modulating host iron homeostasis

(2014) Don-Kyu Kim et al.   NATURE MEDICINE

Nitric oxide–mediated regulation of ferroportin-1 controls macrophage iron homeostasis and immune function in Salmonella infection

(2013) Manfred Nairz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Yersinia Entry into Host Cells Requires Rab5-Dependent Dephosphorylation of PI(4,5)P2 and Membrane Scission

(2012) Helen Sarantis et al.   Cell Host & Microbe

Molecular Mechanism of Hepcidin-Mediated Ferroportin Internalization Requires Ferroportin Lysines, Not Tyrosines or JAK-STAT

(2012) Sandra L. Ross et al.   Cell Metabolism

Hepcidin-Induced Endocytosis of Ferroportin Is Dependent on Ferroportin Ubiquitination

(2012) Bo Qiao et al.   Cell Metabolism

Nutritional immunity: transition metals at the pathogen–host interface

(2012) M. Indriati Hood et al.   NATURE REVIEWS MICROBIOLOGY

The thiol-modifying agent N-ethylmaleimide elevates the cytosolic concentration of free Zn2+ but not of Ca2+ in murine cortical neurons

(2010) Julien Gibon et al.   CELL CALCIUM

Role of Ferroportin in Macrophage-Mediated Immunity

(2010) E. E. Johnson et al.   INFECTION AND IMMUNITY

The myotubularin phosphatase MTMR4 regulates sorting from early endosomes

(2010) M. J. Naughtin et al.   JOURNAL OF CELL SCIENCE

Hereditary hemochromatosis due to resistance to hepcidin: high hepcidin concentrations in a family with C326S ferroportin mutation

(2009) R. L. Sham et al.   BLOOD

The molecular basis of hepcidin-resistant hereditary hemochromatosis

(2009) A. Fernandes et al.   BLOOD

Iron depletion limits intracellular bacterial growth in macrophages

(2008) P. N. Paradkar et al.   BLOOD

Interferon‐γ limits the availability of iron for intramacrophageSalmonella typhimurium

(2008) Manfred Nairz et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Sequential Actions of Myotubularin Lipid Phosphatases Regulate Endosomal PI(3)P and Growth Factor Receptor Trafficking

(2008) Canhong Cao et al.   MOLECULAR BIOLOGY OF THE CELL

agr-Mediated Dispersal of Staphylococcus aureus Biofilms

(2008) Blaise R. Boles et al.   PLoS Pathogens