Strongly deleterious mutations are a primary determinant of extinction risk due to inbreeding depression

Genomic and Fitness Consequences of Genetic Rescue in Wild Populations

(2020) Sarah W. Fitzpatrick et al.   CURRENT BIOLOGY

Purging of highly deleterious mutations through severe bottlenecks in Alpine ibex

(2020) Christine Grossen et al.   Nature Communications

Genetics and extinction and the example of Isle Royale wolves

(2019) P. W. Hedrick et al.   ANIMAL CONSERVATION

Genetic rescue and the maintenance of native ancestry

(2019) Kelley Harris et al.   CONSERVATION GENETICS

Genomic signatures of extensive inbreeding in Isle Royale wolves, a population on the threshold of extinction

(2019) Jacqueline A. Robinson et al.   Science Advances

The Exciting Potential and Remaining Uncertainties of Genetic Rescue

(2019) Donovan A. Bell et al.   TRENDS IN ECOLOGY & EVOLUTION

Ancestry-Dependent Enrichment of Deleterious Homozygotes in Runs of Homozygosity

(2019) Zachary A. Szpiech et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Gene expression drives the evolution of dominance

(2018) Christian D. Huber et al.   Nature Communications

Using Genomic Data to Infer Historic Population Dynamics of Nonmodel Organisms

(2018) Annabel C. Beichman et al.   Annual Review of Ecology Evolution and Systematics

Purging of Strongly Deleterious Mutations Explains Long-Term Persistence and Absence of Inbreeding Depression in Island Foxes

(2018) Jacqueline A. Robinson et al.   CURRENT BIOLOGY

SLiM 3: Forward Genetic Simulations Beyond the Wright–Fisher Model

(2018) Benjamin C Haller et al.   MOLECULAR BIOLOGY AND EVOLUTION

Inference of the Distribution of Selection Coefficients for New Nonsynonymous Mutations Using Large Samples

(2017) Bernard Y. Kim et al.   GENETICS

Settling the score: variant prioritization and Mendelian disease

(2017) Karen Eilbeck et al.   NATURE REVIEWS GENETICS

Determining the factors driving selective effects of new nonsynonymous mutations

(2017) Christian D. Huber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inference of the Distribution of Selection Coefficients for New Nonsynonymous Mutations Using Large Samples

(2017) Bernard Y. Kim et al.   GENETICS

Genomic Flatlining in the Endangered Island Fox

(2016) Jacqueline A. Robinson et al.   CURRENT BIOLOGY

Inbreeding load and purging: implications for the short-term survival and the conservation management of small populations

(2016) A Caballero et al.   HEREDITY

Genetic rescue in a severely inbred wolf population

(2016) Mikael Åkesson et al.   MOLECULAR ECOLOGY

Understanding Inbreeding Depression, Purging, and Genetic Rescue

(2016) Philip W. Hedrick et al.   TRENDS IN ECOLOGY & EVOLUTION

Genetic rescue of small inbred populations: meta-analysis reveals large and consistent benefits of gene flow

(2015) Richard Frankham   MOLECULAR ECOLOGY

Distance from sub-Saharan Africa predicts mutational load in diverse human genomes

(2015) Brenna M. Henn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mountain gorilla genomes reveal the impact of long-term population decline and inbreeding

(2015) Y. Xue et al.   SCIENCE

Genetic rescue to the rescue

(2015) Andrew R. Whiteley et al.   TRENDS IN ECOLOGY & EVOLUTION

Genetic rescue in Isle Royale wolves: genetic analysis and the collapse of the population

(2014) Philip W. Hedrick et al.   CONSERVATION GENETICS

A Test of the ‘Genetic Rescue’ Technique Using Bottlenecked Donor Populations of Drosophila melanogaster

(2012) Sol Heber et al.   PLoS One

The genetic rescue of two bottlenecked South Island robin populations using translocations of inbred donors

(2012) S. Heber et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Reevaluating and Broadening the Definition of Genetic Rescue

(2011) Philip W. Hedrick et al.   CONSERVATION BIOLOGY

Genomic sweep and potential genetic rescue during limiting environmental conditions in an isolated wolf population

(2011) J. R. Adams et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Is lack of evidence of inbreeding depression in a threatened New Zealand robin indicative of reduced genetic load?

(2010) R. J. Laws et al.   ANIMAL CONSERVATION

Inferences About the Distribution of Dominance Drawn From Yeast Gene Knockout Data

(2010) A. F. Agrawal et al.   GENETICS

Genetic Restoration of the Florida Panther

(2010) W. E. Johnson et al.   SCIENCE

The genetics of inbreeding depression

(2009) Deborah Charlesworth et al.   NATURE REVIEWS GENETICS