The effect of statin treatment on intratumoral cholesterol levels and LDL receptor expression: a window-of-opportunity breast cancer trial

Induction of 3-hydroxy-3-methylglutaryl-CoA reductase mediates statin resistance in breast cancer cells

(2019) Andy Göbel et al.   Cell Death & Disease

Window of opportunity clinical trial designs to study cancer metabolism

(2019) Francesca Aroldi et al.   BRITISH JOURNAL OF CANCER

Insensitivity to atorvastatin is associated with increased accumulation of intracellular lipid droplets and fatty acid metabolism in breast cancer cells

(2018) Barbara Lettiero et al.   Scientific Reports

Impact of 27-hydroxylase (CYP27A1) and 27-hydroxycholesterol in breast cancer

(2017) Siker Kimbung et al.   ENDOCRINE-RELATED CANCER

Cholesterol, Cholesterol-Lowering Medication Use, and Breast Cancer Outcome in the BIG 1-98 Study

(2017) Signe Borgquist et al.   JOURNAL OF CLINICAL ONCOLOGY

Trials and Tribulations of CETP Inhibitors

(2017) Alan R. Tall et al.   CIRCULATION RESEARCH

microRNAs in lipoprotein metabolism and cardiometabolic disorders

(2016) Noemi Rotllan et al.   ATHEROSCLEROSIS

Metastasis Stimulation by Hypoxia and Acidosis-Induced Extracellular Lipid Uptake Is Mediated by Proteoglycan-Dependent Endocytosis

(2016) J. A. Menard et al.   CANCER RESEARCH

The role of lipid droplets and adipocytes in cancer. Raman imaging of cell cultures: MCF10A, MCF7, and MDA-MB-231 compared to adipocytes in cancerous human breast tissue

(2015) Halina Abramczyk et al.   ANALYST

Intratumor cholesteryl ester accumulation is associated with human breast cancer proliferation and aggressive potential: a molecular and clinicopathological study

(2015) David de Gonzalo-Calvo et al.   BMC CANCER

Global Transcriptional Changes Following Statin Treatment in Breast Cancer

(2015) O. Bjarnadottir et al.   CLINICAL CANCER RESEARCH

MicroRNA-148a regulates LDL receptor and ABCA1 expression to control circulating lipoprotein levels

(2015) Leigh Goedeke et al.   NATURE MEDICINE

Immediate Utility of Two Approved Agents to Target Both the Metabolic Mevalonate Pathway and Its Restorative Feedback Loop

(2014) Aleksandra Pandyra et al.   CANCER RESEARCH

Statins and breast cancer prognosis: evidence and opportunities

(2014) Thomas P Ahern et al.   LANCET ONCOLOGY

Statin Use and Breast Cancer Survival: A Nationwide Cohort Study from Finland

(2014) Teemu J. Murtola et al.   PLoS One

Statin induces inhibition of triple negative breast cancer (TNBC) cells via PI3K pathway

(2013) Yeon Hee Park et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Targeting HMG-CoA reductase with statins in a window-of-opportunity breast cancer trial

(2013) Olöf Bjarnadottir et al.   BREAST CANCER RESEARCH AND TREATMENT

Lovastatin-induced decrease of intracellular cholesterol level attenuates fibroblast-to-myofibroblast transition in bronchial fibroblasts derived from asthmatic patients

(2013) Marta Michalik et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

NDRG1 functions in LDL receptor trafficking by regulating endosomal recycling and degradation

(2013) V. Pietiainen et al.   JOURNAL OF CELL SCIENCE

Effect of neoadjuvant chemotherapy on low-density lipoprotein (LDL) receptor and LDL receptor-related protein 1 (LRP-1) receptor in locally advanced breast cancer

(2012) L.A. Pires et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment

(2012) Douglas Hanahan et al.   CANCER CELL

Simvastatin inhibition of mevalonate pathway induces apoptosis in human breast cancer cells via activation of JNK/CHOP/DR5 signaling pathway

(2012) Archana Gopalan et al.   CANCER LETTERS

Lipid metabolism in cancer

(2012) Claudio R. Santos et al.   FEBS Journal

How cancer metabolism is tuned for proliferation and vulnerable to disruption

(2012) Almut Schulze et al.   NATURE

Statin Use and Reduced Cancer-Related Mortality

(2012) Sune F. Nielsen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Lipid Droplet De Novo Formation and Fission Are Linked to the Cell Cycle in Fission Yeast

(2012) Allan P. Long et al.   TRAFFIC

Ki67 proliferation in core biopsies versus surgical samples - a model for neo-adjuvant breast cancer studies

(2011) Quinci Romero et al.   BMC CANCER

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Regulation of cholesterol homeostasis

(2011) Leigh Goedeke et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Statin Prescriptions and Breast Cancer Recurrence Risk: A Danish Nationwide Prospective Cohort Study

(2011) T. P. Ahern et al.   JNCI-Journal of the National Cancer Institute

Accumulation and aberrant composition of cholesteryl esters in Scrapie-infected N2a cells and C57BL/6 mouse brains

(2011) Sarah Vascellari et al.   Lipids in Health and Disease

Simvastatin induces derepression of PTEN expression via NFκB to inhibit breast cancer cell growth

(2010) Nayana Ghosh-Choudhury et al.   CELLULAR SIGNALLING

Apolipoprotein B100 secretion by cultured ARPE-19 cells is modulated by alteration of cholesterol levels

(2010) Tinghuai Wu et al.   JOURNAL OF NEUROCHEMISTRY

Lipid droplets in inflammation and cancer

(2010) Patricia T. Bozza et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Acyl-coenzyme A:cholesterol acyltransferases

(2009) Ta-Yuan Chang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The LDL Receptor

(2009) Joseph L. Goldstein et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Liver X receptor in cholesterol metabolism

(2009) Chunyan Zhao et al.   JOURNAL OF ENDOCRINOLOGY

A re-annotation pipeline for Illumina BeadArrays: improving the interpretation of gene expression data

(2009) Nuno L. Barbosa-Morais et al.   NUCLEIC ACIDS RESEARCH