Insensitivity to atorvastatin is associated with increased accumulation of intracellular lipid droplets and fatty acid metabolism in breast cancer cells
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Insensitivity to atorvastatin is associated with increased accumulation of intracellular lipid droplets and fatty acid metabolism in breast cancer cells
Authors
Keywords
-
Journal
Scientific Reports
Volume 8, Issue 1, Pages -
Publisher
Springer Nature
Online
2018-03-26
DOI
10.1038/s41598-018-23726-3
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Impact of 27-hydroxylase (CYP27A1) and 27-hydroxycholesterol in breast cancer
- (2017) Siker Kimbung et al. ENDOCRINE-RELATED CANCER
- Cholesterol, Cholesterol-Lowering Medication Use, and Breast Cancer Outcome in the BIG 1-98 Study
- (2017) Signe Borgquist et al. JOURNAL OF CLINICAL ONCOLOGY
- The ACAT2 expression of human leukocytes is responsible for the excretion of lipoproteins containing cholesteryl/steryl esters
- (2016) Dongqing Guo et al. ACTA BIOCHIMICA ET BIOPHYSICA SINICA
- High expression of cholesterol biosynthesis genes is associated with resistance to statin treatment and inferior survival in breast cancer
- (2016) Siker Kimbung et al. Oncotarget
- The role of lipid droplets and adipocytes in cancer. Raman imaging of cell cultures: MCF10A, MCF7, and MDA-MB-231 compared to adipocytes in cancerous human breast tissue
- (2015) Halina Abramczyk et al. ANALYST
- A Century of Cholesterol and Coronaries: From Plaques to Genes to Statins
- (2015) Joseph L. Goldstein et al. CELL
- Global Transcriptional Changes Following Statin Treatment in Breast Cancer
- (2015) O. Bjarnadottir et al. CLINICAL CANCER RESEARCH
- Expanding Roles for Lipid Droplets
- (2015) Michael A. Welte CURRENT BIOLOGY
- Statin-induced anti-proliferative effects via cyclin D1 and p27 in a window-of-opportunity breast cancer trial
- (2015) Maria Feldt et al. Journal of Translational Medicine
- Genome-wide RNAi analysis reveals that simultaneous inhibition of specific mevalonate pathway genes potentiates tumor cell death
- (2015) Aleksandra A. Pandyra et al. Oncotarget
- In vitro and in vivo anticancer effects of mevalonate pathway modulation on human cancer cells
- (2014) P Jiang et al. BRITISH JOURNAL OF CANCER
- Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012
- (2014) Jacques Ferlay et al. INTERNATIONAL JOURNAL OF CANCER
- Statins and breast cancer prognosis: evidence and opportunities
- (2014) Thomas P Ahern et al. LANCET ONCOLOGY
- Targeting HMG-CoA reductase with statins in a window-of-opportunity breast cancer trial
- (2013) Olöf Bjarnadottir et al. BREAST CANCER RESEARCH AND TREATMENT
- Identifying molecular features that distinguish fluvastatin-sensitive breast tumor cells
- (2013) Carolyn A. Goard et al. BREAST CANCER RESEARCH AND TREATMENT
- Cell Survival during Complete Nutrient Deprivation Depends on Lipid Droplet-fueled β-Oxidation of Fatty Acids
- (2013) Ainara G. Cabodevilla et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- 27-Hydroxycholesterol Links Hypercholesterolemia and Breast Cancer Pathophysiology
- (2013) E. R. Nelson et al. SCIENCE
- Apoptosis-induced mitochondrial dysfunction causes cytoplasmic lipid droplet formation
- (2012) J Boren et al. CELL DEATH AND DIFFERENTIATION
- Statin Use and Reduced Cancer-Related Mortality
- (2012) Sune F. Nielsen et al. NEW ENGLAND JOURNAL OF MEDICINE
- Targeting tumor cell metabolism with statins
- (2012) J W Clendening et al. ONCOGENE
- Statin Prescriptions and Breast Cancer Recurrence Risk: A Danish Nationwide Prospective Cohort Study
- (2011) T. P. Ahern et al. JNCI-Journal of the National Cancer Institute
- Roles of StearoylCoA Desaturase-1 in the Regulation of Cancer Cell Growth, Survival and Tumorigenesis
- (2011) R. Ariel Igal Cancers
- Simvastatin induces derepression of PTEN expression via NFκB to inhibit breast cancer cell growth
- (2010) Nayana Ghosh-Choudhury et al. CELLULAR SIGNALLING
- Dysregulation of the mevalonate pathway promotes transformation
- (2010) J. W. Clendening et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Acyl-CoA synthesis, lipid metabolism and lipotoxicity
- (2009) Lei O. Li et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Fluvastatin reduces proliferation and increases apoptosis in women with high grade breast cancer
- (2009) Elisabeth R. Garwood et al. BREAST CANCER RESEARCH AND TREATMENT
- High ACAT1 expression in estrogen receptor negative basal-like breast cancer cells is associated with LDL-induced proliferation
- (2009) Caryl J. Antalis et al. BREAST CANCER RESEARCH AND TREATMENT
- Lipid Droplet Biogenesis Induced by Stress Involves Triacylglycerol Synthesis That Depends on Group VIA Phospholipase A2
- (2009) Albert Gubern et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Demonstrated and inferred metabolism associated with cytosolic lipid droplets: TABLE 1.
- (2009) Joel M. Goodman JOURNAL OF LIPID RESEARCH
- Inhibition of StearoylCoA Desaturase-1 Inactivates Acetyl-CoA Carboxylase and Impairs Proliferation in Cancer Cells: Role of AMPK
- (2009) Natalia Scaglia et al. PLoS One
- Biochemical and physiological function of stearoyl-CoA desaturase
- (2008) Chad M. Paton et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Cholesterol feedback: from Schoenheimer's bottle to Scap's MELADL
- (2008) Michael S. Brown et al. JOURNAL OF LIPID RESEARCH
- Analyzing real-time PCR data by the comparative CT method
- (2008) Thomas D Schmittgen et al. Nature Protocols
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started