Computational Analysis of African Swine Fever Virus Protein Space for the Design of an Epitope-Based Vaccine Ensemble

Development of a highly effective African swine fever virus vaccine by deletion of the I177L gene results in sterile immunity against the current epidemic Eurasia strain.

(2020) Manuel V. Borca et al.   JOURNAL OF VIROLOGY

A seven-gene-deleted African swine fever virus is safe and effective as a live attenuated vaccine in pigs

(2020) Weiye Chen et al.   Science China-Life Sciences

Deletion of CD2-like gene from the genome of African swine fever virus strain Georgia does not attenuate virulence in swine

(2020) Manuel V. Borca et al.   Scientific Reports

Progress Toward Development of Effective and Safe African Swine Fever Virus Vaccines

(2020) Huldah Sang et al.   Frontiers in Veterinary Science

Design of an Epitope-Based Vaccine Ensemble for Animal Trypanosomiasis by Computational Methods

(2020) Lucas Michel-Todó et al.   Vaccines

African Swine Fever Virus: An Emerging DNA Arbovirus

(2020) Natasha N. Gaudreault et al.   Frontiers in Veterinary Science

Impaired T‐cell responses in domestic pigs and wild boar upon infection with a highly virulent African swine fever virus strain

(2020) Jane Hühr et al.   Transboundary and Emerging Diseases

Fecal microbiota transplantation from warthog to pig confirms the influence of the gut microbiota on African swine fever susceptibility

(2020) Jinya Zhang et al.   Scientific Reports

African swine fever

(2019) L.K. Dixon et al.   ANTIVIRAL RESEARCH

IEDB-AR: immune epitope database—analysis resource in 2019

(2019) Sandeep Kumar Dhanda et al.   NUCLEIC ACIDS RESEARCH

The Development of a Vaccine Against Meningococcus B Using Reverse Vaccinology

(2019) Vega Masignani et al.   Frontiers in Immunology

Identification and Immunogenicity of African Swine Fever Virus Antigens

(2019) Christopher L. Netherton et al.   Frontiers in Immunology

Subunit Vaccine Approaches for African Swine Fever Virus

(2019) Natasha N. Gaudreault et al.   Vaccines

Structure of the African swine fever virus major capsid protein p72

(2019) Qi Liu et al.   CELL RESEARCH

Adenovirus-vectored African Swine Fever Virus antigen cocktails are immunogenic but not protective against intranasal challenge with Georgia 2007/1 isolate

(2019) Shehnaz Lokhandwala et al.   VETERINARY MICROBIOLOGY

The cryo-EM structure of African swine fever virus unravels a unique architecture comprising two icosahedral protein capsids and two lipoprotein membranes

(2019) German Andres et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Architecture of African swine fever virus and implications for viral assembly

(2019) Nan Wang et al.   SCIENCE

Comparative analysis of the fecal microbiota from different species of domesticated and wild suids

(2019) Florencia Correa-Fiz et al.   Scientific Reports

African Swine Fever Epidemiology and Control

(2019) Linda K. Dixon et al.   Annual Review of Animal Biosciences

Computational assembly of a human Cytomegalovirus vaccine upon experimental epitope legacy

(2019) Monica J. Quinzo et al.   BMC BIOINFORMATICS

Cryo-EM Structure of the African Swine Fever Virus

(2019) Sheng Liu et al.   Cell Host & Microbe

Cross-modality deep learning-based prediction of TAP binding and naturally processed peptide

(2018) Hanan Besser et al.   IMMUNOGENETICS

Immunization of Pigs by DNA Prime and Recombinant Vaccinia Virus Boost To Identify and Rank African Swine Fever Virus Immunogenic and Protective Proteins

(2018) James K. Jancovich et al.   JOURNAL OF VIROLOGY

A proteomic atlas of the African swine fever virus particle

(2018) Alí Alejo et al.   JOURNAL OF VIROLOGY

UniProt: a worldwide hub of protein knowledge

(2018)   NUCLEIC ACIDS RESEARCH

The Immune Epitope Database (IEDB): 2018 update

(2018) Randi Vita et al.   NUCLEIC ACIDS RESEARCH

Infection, modulation and responses of antigen-presenting cells to African swine fever viruses

(2018) Giulia Franzoni et al.   VIRUS RESEARCH

BA71ΔCD2: a New Recombinant Live Attenuated African Swine Fever Virus with Cross-Protective Capabilities

(2017) Paula L. Monteagudo et al.   JOURNAL OF VIROLOGY

BepiPred-2.0: improving sequence-based B-cell epitope prediction using conformational epitopes

(2017) Martin Closter Jespersen et al.   NUCLEIC ACIDS RESEARCH

Computer-Aided Design of an Epitope-Based Vaccine against Epstein-Barr Virus

(2017) Julio Alonso-Padilla et al.   Journal of Immunology Research

Towards the knowledge-based design of universal influenza epitope ensemble vaccines

(2016) Qamar M. Sheikh et al.   BIOINFORMATICS

Piglet nasal microbiota at weaning may influence the development of Glässer’s disease during the rearing period

(2016) Florencia Correa-Fiz et al.   BMC GENOMICS

Simultaneous Deletion of the 9GL and UK Genes from the African Swine Fever Virus Georgia 2007 Isolate Offers Increased Safety and Protection against Homologous Challenge

(2016) Vivian O'Donnell et al.   JOURNAL OF VIROLOGY

Transmission routes of African swine fever virus to domestic pigs: current knowledge and future research directions

(2016) Claire Guinat et al.   VETERINARY RECORD

Genome Sequence of African Swine Fever Virus BA71, the Virulent Parental Strain of the Nonpathogenic and Tissue-Culture Adapted BA71V

(2015) Javier M. Rodríguez et al.   PLoS One

Related strains of African swine fever virus with different virulence: genome comparison and analysis

(2014) R. Portugal et al.   JOURNAL OF GENERAL VIROLOGY

Expression Library Immunization Can Confer Protection against Lethal Challenge with African Swine Fever Virus

(2014) A. Lacasta et al.   JOURNAL OF VIROLOGY

Modern Subunit Vaccines: Development, Components, and Research Opportunities

(2013) Peter Michael Moyle et al.   ChemMedChem

Developing vaccines in the era of genomics: a decade of reverse vaccinology

(2012) K.L. Seib et al.   CLINICAL MICROBIOLOGY AND INFECTION

DNA Vaccination Partially Protects against African Swine Fever Virus Lethal Challenge in the Absence of Antibodies

(2012) Jordi M. Argilaguet et al.   PLoS One

Antibody-mediated neutralization of African swine fever virus: Myths and facts

(2012) José M. Escribano et al.   VIRUS RESEARCH

Cellular immunity in ASFV responses

(2012) Haru-Hisa Takamatsu et al.   VIRUS RESEARCH

African swine fever virus morphogenesis

(2012) María L. Salas et al.   VIRUS RESEARCH

African swine fever virus replication and genomics

(2012) Linda K. Dixon et al.   VIRUS RESEARCH

Functional classification of class II human leukocyte antigen (HLA) molecules reveals seven different supertypes and a surprising degree of repertoire sharing across supertypes

(2011) Jason Greenbaum et al.   IMMUNOGENETICS

Universal peptide vaccines – Optimal peptide vaccine design based on viral sequence conservation

(2011) Nora C. Toussaint et al.   VACCINE

Enhancing DNA immunization by targeting ASFV antigens to SLA-II bearing cells

(2011) J.M. Argilaguet et al.   VACCINE

African swine fever: how can global spread be prevented?

(2009) S. Costard et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

PredGPI: a GPI-anchor predictor

(2008) Andrea Pierleoni et al.   BMC BIOINFORMATICS

Comparison of the genome sequences of non-pathogenic and pathogenic African swine fever virus isolates

(2008) D. A. G. Chapman et al.   JOURNAL OF GENERAL VIROLOGY

Enhanced discrimination of African swine fever virus isolates through nucleotide sequencing of the p54, p72, and pB602L (CVR) genes

(2008) Carmina Gallardo et al.   VIRUS GENES