Combating the Pandemic COVID-19: Clinical Trials, Therapies and Perspectives
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Combating the Pandemic COVID-19: Clinical Trials, Therapies and Perspectives
Authors
Keywords
-
Journal
Frontiers in Molecular Biosciences
Volume 7, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2020-11-17
DOI
10.3389/fmolb.2020.606393
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Novel Wuhan (2019-nCoV) Coronavirus
- (2020) W. Graham Carlos et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro
- (2020) Manli Wang et al. CELL RESEARCH
- The novel Chinese coronavirus (2019‐nCoV) infections: Challenges for fighting the storm
- (2020) Matteo Bassetti et al. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
- Chloroquine for the 2019 novel coronavirus SARS-CoV-2
- (2020) Philippe Colson et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Preliminary estimation of the basic reproduction number of novel coronavirus (2019-nCoV) in China, from 2019 to 2020: A data-driven analysis in the early phase of the outbreak
- (2020) Shi Zhao et al. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
- The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak
- (2020) Hussin A. Rothan et al. JOURNAL OF AUTOIMMUNITY
- The antiviral compound remdesivir potently inhibits RNA-dependent RNA polymerase from Middle East respiratory syndrome coronavirus
- (2020) Calvin J Gordon et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cross‐species transmission of the newly identified coronavirus 2019‐nCoV
- (2020) Wei Ji et al. JOURNAL OF MEDICAL VIROLOGY
- Outbreak of pneumonia of unknown etiology in Wuhan, China: The mystery and the miracle
- (2020) Hongzhou Lu et al. JOURNAL OF MEDICAL VIROLOGY
- Pneumonia of unknown aetiology in Wuhan, China: potential for international spread via commercial air travel
- (2020) Isaac I Bogoch et al. JOURNAL OF TRAVEL MEDICINE
- Baricitinib as potential treatment for 2019-nCoV acute respiratory disease
- (2020) Peter Richardson et al. LANCET
- Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding
- (2020) Roujian Lu et al. LANCET
- Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
- (2020) Chaolin Huang et al. LANCET
- Convalescent plasma as a potential therapy for COVID-19
- (2020) Long Chen et al. LANCET INFECTIOUS DISEASES
- First Case of 2019 Novel Coronavirus in the United States
- (2020) Michelle L. Holshue et al. NEW ENGLAND JOURNAL OF MEDICINE
- Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus–Infected Pneumonia
- (2020) Qun Li et al. NEW ENGLAND JOURNAL OF MEDICINE
- Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection
- (2020) Emmie de Wit et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- CT Imaging of the 2019 Novel Coronavirus (2019-nCoV) Pneumonia
- (2020) Junqiang Lei et al. RADIOLOGY
- Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody
- (2020) Xiaolong Tian et al. Emerging Microbes & Infections
- Therapeutic and triage strategies for 2019 novel coronavirus disease in fever clinics
- (2020) Jinnong Zhang et al. Lancet Respiratory Medicine
- Analysis of therapeutic targets for SARS-CoV-2 and discovery of potential drugs by computational methods
- (2020) Canrong Wu et al. Acta Pharmaceutica Sinica B
- Tocilizumab, an anti-IL-6 receptor antibody, to treat COVID-19-related respiratory failure: a case report
- (2020) J.-M. Michot et al. ANNALS OF ONCOLOGY
- COVID-19 in a patient with systemic sclerosis treated with tocilizumab for SSc-ILD
- (2020) Carina Mihai et al. ANNALS OF THE RHEUMATIC DISEASES
- Of chloroquine and COVID-19
- (2020) Franck Touret et al. ANTIVIRAL RESEARCH
- Convalescent plasma in Covid-19: Possible mechanisms of action
- (2020) Manuel Rojas et al. AUTOIMMUNITY REVIEWS
- Chimeric Antigen Receptor T Cell Therapy During the COVID-19 Pandemic
- (2020) Veronika Bachanova et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
- (2020) Markus Hoffmann et al. CELL
- Identification of a novel coronavirus causing severe pneumonia in human
- (2020) Li-Li Ren et al. CHINESE MEDICAL JOURNAL
- Clinical Features of 69 Cases With Coronavirus Disease 2019 in Wuhan, China
- (2020) Zhongliang Wang et al. CLINICAL INFECTIOUS DISEASES
- In Vitro Antiviral Activity and Projection of Optimized Dosing Design of Hydroxychloroquine for the Treatment of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
- (2020) Xueting Yao et al. CLINICAL INFECTIOUS DISEASES
- Favipiravir: Pharmacokinetics and Concerns About Clinical Trials for 2019‐nCoV Infection
- (2020) Yin‐Xiao Du et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- SARS CoV-2: Recent Reports on Antiviral Therapies Based on Lopinavir/Ritonavir, Darunavir/Umifenovir, Hydroxychloroquine, Remdesivir, Favipiravir and Other Drugs for the Treatment of the New Coronavirus
- (2020) Michele Costanzo et al. CURRENT MEDICINAL CHEMISTRY
- The cytokine storm in COVID-19: An overview of the involvement of the chemokine/chemokine-receptor system
- (2020) Francesca Coperchini et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Cell-Based Therapies for COVID-19: Proper Clinical Investigations are Essential
- (2020) Maroun Khoury et al. CYTOTHERAPY
- A case of exacerbation of psoriasis after oseltamivir and hydroxychloroquine in a patient with COVID ‐19: Will cases of psoriasis increase after COVID ‐19 pandemic?
- (2020) Ömer Kutlu et al. Dermatologic Therapy
- Déjà vu: Stimulating open drug discovery for SARS-CoV-2
- (2020) Sean Ekins et al. DRUG DISCOVERY TODAY
- Controversies about COVID-19 and anticancer treatment with immune checkpoint inhibitors
- (2020) Melissa Bersanelli Immunotherapy
- The correlation between viral clearance and biochemical outcomes of 94 COVID-19 infected discharged patients
- (2020) Jing Yuan et al. INFLAMMATION RESEARCH
- Perspectives: potential therapeutic options for SARS-CoV-2 patients based on feline infectious peritonitis strategies: central nervous system invasion and drug coverage
- (2020) Mark Olsen et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Janus kinase inhibitor baricitinib is not an ideal option for management of COVID-19
- (2020) D. Praveen et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- The epidemiology, diagnosis and treatment of COVID-19
- (2020) Pan Zhai et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- New insights on the antiviral effects of chloroquine against coronavirus: what to expect for COVID-19?
- (2020) Christian A. Devaux et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Review of the 2019 novel coronavirus (SARS-CoV-2) based on current evidence
- (2020) Lisheng Wang et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Cytokine release syndrome in severe COVID-19: interleukin-6 receptor antagonist tocilizumab may be the key to reduce mortality
- (2020) Chi Zhang et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Coronavirus disease 2019 (COVID-19): current status and future perspectives
- (2020) Heng Li et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial
- (2020) Philippe Gautret et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Recurrence of positive SARS-CoV-2 RNA in COVID-19: A case report
- (2020) Dabiao Chen et al. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
- Convalescent Plasma to Treat COVID-19
- (2020) John D. Roback et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Treatment of 5 Critically Ill Patients With COVID-19 With Convalescent Plasma
- (2020) Chenguang Shen et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Recommendations for coronavirus infection in rheumatic diseases treated with biologic therapy
- (2020) Angela Ceribelli et al. JOURNAL OF AUTOIMMUNITY
- Computational studies of drug repurposing and synergism of lopinavir, oseltamivir and ritonavir binding with SARS-CoV-2 protease against COVID-19
- (2020) Nisha Muralidharan et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- Deployment of convalescent plasma for the prevention and treatment of COVID-19
- (2020) Evan M. Bloch et al. JOURNAL OF CLINICAL INVESTIGATION
- Arbidol combined with LPV/r versus LPV/r alone against Corona Virus Disease 2019: A retrospective cohort study
- (2020) Lisi Deng et al. JOURNAL OF INFECTION
- Tocilizumab treatment in COVID-19: A single center experience
- (2020) Pan Luo et al. JOURNAL OF MEDICAL VIROLOGY
- The clinical characteristics of pneumonia patients coinfected with 2019 novel coronavirus and influenza virus in Wuhan, China
- (2020) Qiang Ding et al. JOURNAL OF MEDICAL VIROLOGY
- Treatment options for COVID-19: The reality and challenges
- (2020) Shio-Shin Jean et al. JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION
- Anti-IL6R role in treatment of COVID-19-related ARDS
- (2020) Franco Maria Buonaguro et al. Journal of Translational Medicine
- Why tocilizumab could be an effective treatment for severe COVID-19?
- (2020) Binqing Fu et al. Journal of Translational Medicine
- Hopes rise for coronavirus drug remdesivir
- (2020) Heidi Ledford NATURE
- Insights from nanomedicine into chloroquine efficacy against COVID-19
- (2020) Tony Y. Hu et al. Nature Nanotechnology
- A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19
- (2020) Bin Cao et al. NEW ENGLAND JOURNAL OF MEDICINE
- Aerosol and Surface Stability of SARS-CoV-2 as Compared with SARS-CoV-1
- (2020) Neeltje van Doremalen et al. NEW ENGLAND JOURNAL OF MEDICINE
- New therapeutic opportunities for COVID-19 patients with Tocilizumab: Possible correlation of interleukin-6 receptor inhibitors with osteonecrosis of the jaws
- (2020) Francesco Bennardo et al. ORAL ONCOLOGY
- Effective treatment of severe COVID-19 patients with tocilizumab
- (2020) Xiaoling Xu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Effectiveness of convalescent plasma therapy in severe COVID-19 patients
- (2020) Kai Duan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Race to find COVID-19 treatments accelerates
- (2020) Kai Kupferschmidt et al. SCIENCE
- Repurposing Antiviral Protease Inhibitors Using Extracellular Vesicles for Potential Therapy of COVID-19
- (2020) Santosh Kumar et al. Viruses-Basel
- Drug treatment options for the 2019-new coronavirus (2019-nCoV)
- (2020) Hongzhou Lu BioScience Trends
- Breakthrough: Chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies
- (2020) Jianjun Gao et al. BioScience Trends
- Clinical characteristics and therapeutic procedure for four cases with 2019 novel coronavirus pneumonia receiving combined Chinese and Western medicine treatment
- (2020) Zhenwei Wang et al. BioScience Trends
- Covid-19: FDA approves use of convalescent plasma to treat critically ill patients
- (2020) Janice Hopkins Tanne BMJ-British Medical Journal
- Airborne Transmission Route of COVID-19: Why 2 Meters/6 Feet of Inter-Personal Distance Could Not Be Enough
- (2020) Leonardo Setti et al. International Journal of Environmental Research and Public Health
- Favorable changes of CT findings in a patient with COVID-19 pneumonia after treatment with tocilizumab
- (2020) M. Cellina et al. Diagnostic and Interventional Imaging
- Impact of immune enhancement on Covid-19 polyclonal hyperimmune globulin therapy and vaccine development
- (2020) Ruklanthi de Alwis et al. EBioMedicine
- The COVID-19 Pandemic: A Comprehensive Review of Taxonomy, Genetics, Epidemiology, Diagnosis, Treatment, and Control
- (2020) Yosra A. Helmy et al. Journal of Clinical Medicine
- Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro
- (2020) Jia Liu et al. Cell Discovery
- Structural basis of SARS-CoV-2 3CLpro and anti-COVID-19 drug discovery from medicinal plants
- (2020) Muhammad Tahir ul Qamar et al. Journal of Pharmaceutical Analysis
- Molecular immune pathogenesis and diagnosis of COVID-19
- (2020) Xiaowei Li et al. Journal of Pharmaceutical Analysis
- Origin, Potential Therapeutic Targets and Treatment for Coronavirus Disease (COVID-19)
- (2020) Muhammad Shahid Nadeem et al. Pathogens
- Remdesivir and SARS-CoV-2: Structural requirements at both nsp12 RdRp and nsp14 Exonuclease active-sites
- (2020) Ashleigh Shannon et al. ANTIVIRAL RESEARCH
- The FDA-approved drug ivermectin inhibits the replication of SARS-CoV-2 in vitro
- (2020) Leon Caly et al. ANTIVIRAL RESEARCH
- Remdesivir, lopinavir, emetine, and homoharringtonine inhibit SARS-CoV-2 replication in vitro
- (2020) Ka-Tim Choy et al. ANTIVIRAL RESEARCH
- Type 1 interferons as a potential treatment against COVID-19
- (2020) Erwan Sallard et al. ANTIVIRAL RESEARCH
- Organ-specific manifestations of COVID-19 infection
- (2020) Maria Gavriatopoulou et al. CLINICAL AND EXPERIMENTAL MEDICINE
- COVID-19 treatment: close to a cure? A rapid review of pharmacotherapies for the novel coronavirus (SARS-CoV-2)
- (2020) Yang Song et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Can we use interleukin-6 (IL-6) blockade for coronavirus disease 2019 (COVID-19)-induced cytokine release syndrome (CRS)?
- (2020) Bingwen Liu et al. JOURNAL OF AUTOIMMUNITY
- Challenges of Convalescent Plasma Therapy on COVID-19
- (2020) Qian Zhao et al. JOURNAL OF CLINICAL VIROLOGY
- A systematic review on the efficacy and safety of chloroquine for the treatment of COVID-19
- (2020) Andrea Cortegiani et al. JOURNAL OF CRITICAL CARE
- Ribavirin, Remdesivir, Sofosbuvir, Galidesivir, and Tenofovir against SARS-CoV-2 RNA dependent RNA polymerase (RdRp): A molecular docking study
- (2020) Abdo A. Elfiky LIFE SCIENCES
- In silico studies on therapeutic agents for COVID-19: Drug repurposing approach
- (2020) Bhumi Shah et al. LIFE SCIENCES
- Virtual screening and repurposing of FDA approved drugs against COVID-19 main protease
- (2020) Mahmoud Kandeel et al. LIFE SCIENCES
- The powerful immune system against powerful COVID-19: A hypothesis
- (2020) Farzad Taghizadeh-Hesary et al. MEDICAL HYPOTHESES
- Plausible mechanisms of Niclosamide as an antiviral agent against COVID-19
- (2020) Sai Kiran S.S. Pindiprolu et al. MEDICAL HYPOTHESES
- Amantadine as a drug to mitigate the effects of COVID-19
- (2020) Gonzalo Emiliano Aranda Abreu et al. MEDICAL HYPOTHESES
- Clinical remission of a critically ill COVID-19 patient treated by human umbilical cord mesenchymal stem cells
- (2020) Bing Liang et al. MEDICINE
- Nitazoxanide/azithromycin combination for COVID-19: A suggested new protocol for early management
- (2020) Mina T. Kelleni PHARMACOLOGICAL RESEARCH
- Candidate drugs against SARS-CoV-2 and COVID-19
- (2020) Dwight L. McKee et al. PHARMACOLOGICAL RESEARCH
- COVID-19: A promising cure for the global panic
- (2020) Balachandar Vellingiri et al. SCIENCE OF THE TOTAL ENVIRONMENT
- Lung Surfactant for Pulmonary Barrier Restoration in Patients With COVID-19 Pneumonia
- (2020) Ursula Mirastschijski et al. Frontiers in Medicine
- Current scenario and future prospect in the management of COVID-19
- (2020) Pobitra Borah et al. CURRENT MEDICINAL CHEMISTRY
- Etoposide-based therapy for severe forms of COVID-19
- (2020) Kamel Hamizi et al. MEDICAL HYPOTHESES
- Exercise as medicine for COVID-19: An ACE in the hole?
- (2020) Kevin S. Heffernan et al. MEDICAL HYPOTHESES
- As a potential treatment of COVID-19: Montelukast
- (2020) Cihan Fidan et al. MEDICAL HYPOTHESES
- Is the anti-filarial drug diethylcarbamazine useful to treat COVID-19?
- (2020) Anuruddha Abeygunasekera et al. MEDICAL HYPOTHESES
- Surfactant-based prophylaxis and therapy against COVID-19: A possibility
- (2020) K. Pramod et al. MEDICAL HYPOTHESES
- Is copper beneficial for COVID-19 patients?
- (2020) Syamal Raha et al. MEDICAL HYPOTHESES
- Does zinc supplementation enhance the clinical efficacy of chloroquine/hydroxychloroquine to win today's battle against COVID-19?
- (2020) R. Derwand et al. MEDICAL HYPOTHESES
- Efficacy and tolerability of sofosbuvir and daclatasvir for treatment of hepatitis C genotype 1 & 3 in patients undergoing hemodialysis- a prospective interventional clinical trial
- (2019) Shafiq Ur Rehman Cheema et al. BMC Nephrology
- The Interplay of Viral and Host Factors in Chikungunya Virus Infection: Targets for Antiviral Strategies
- (2018) Kai Zhi Wong et al. Viruses-Basel
- SARS and MERS: recent insights into emerging coronaviruses
- (2016) Emmie de Wit et al. NATURE REVIEWS MICROBIOLOGY
- Combination therapy with lopinavir/ritonavir, ribavirin and interferon-alpha for Middle East respiratory syndrome: a case report
- (2015) Uh Jin Kim et al. ANTIVIRAL THERAPY
- Arbidol as a broad-spectrum antiviral: An update
- (2014) Julie Blaising et al. ANTIVIRAL RESEARCH
- pH-dependent entry of chikungunya virus into Aedes albopictus cells
- (2012) Bernard Gay et al. INFECTION GENETICS AND EVOLUTION
- Theoretical Studies on the Susceptibility of Oseltamivir against Variants of 2009 A/H1N1 Influenza Neuraminidase
- (2012) Lin Li et al. Journal of Chemical Information and Modeling
- Effect of metronidazole and modulation of cytokine production on human periodontal ligament cells
- (2010) Antonietta Rizzo et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Evaluation of immunosuppression induced by metronidazole in Balb/c mice and human peripheral blood lymphocytes
- (2007) Mohammad Fararjeh et al. INTERNATIONAL IMMUNOPHARMACOLOGY
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started