Severe COVID-19 and Sepsis: Immune Pathogenesis and Laboratory Markers

Laboratory abnormalities in patients with COVID-2019 infection

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Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus–Infected Pneumonia in Wuhan, China

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Coronavirus infections and immune responses

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Abnormal Coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia

(2020) Ning Tang et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

(2020) Chaolin Huang et al.   LANCET

Pathological findings of COVID-19 associated with acute respiratory distress syndrome

(2020) Zhe Xu et al.   Lancet Respiratory Medicine

Insights into the Recent 2019 Novel Coronavirus (SARS-CoV-2) in Light of Past Human Coronavirus Outbreaks

(2020) Hossam M. Ashour et al.   Pathogens

Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19

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Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein

(2020) Alexandra C. Walls et al.   CELL

Functional exhaustion of antiviral lymphocytes in COVID-19 patients

(2020) Meijuan Zheng et al.   Cellular & Molecular Immunology

The critical role of laboratory medicine during coronavirus disease 2019 (COVID-19) and other viral outbreaks

(2020) Giuseppe Lippi et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Hematologic, biochemical and immune biomarker abnormalities associated with severe illness and mortality in coronavirus disease 2019 (COVID-19): a meta-analysis

(2020) Brandon Michael Henry et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Comparative replication and immune activation profiles of SARS-CoV-2 and SARS-CoV in human lungs: an ex vivo study with implications for the pathogenesis of COVID-19

(2020) Hin Chu et al.   CLINICAL INFECTIOUS DISEASES

Dysregulation of Immune Response in Patients With Coronavirus 2019 (COVID-19) in Wuhan, China

(2020) Chuan Qin et al.   CLINICAL INFECTIOUS DISEASES

The unleashing of the immune system in COVID-19 and sepsis: the calm before the storm?

(2020) Salvatore Bellinvia et al.   INFLAMMATION RESEARCH

Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study

(2020) Fei Zhou et al.   LANCET

COVID-19: consider cytokine storm syndromes and immunosuppression

(2020) Puja Mehta et al.   LANCET

Human neutralizing antibodies elicited by SARS-CoV-2 infection

(2020) Bin Ju et al.   NATURE

Substantial undocumented infection facilitates the rapid dissemination of novel coronavirus (SARS-CoV-2)

(2020) Ruiyun Li et al.   SCIENCE

World Health Organization declares global emergency: A review of the 2019 novel coronavirus (COVID-19)

(2020) Catrin Sohrabi et al.   International Journal of Surgery

Clinical, laboratory and imaging features of COVID-19: A systematic review and meta-analysis

(2020) Alfonso J. Rodriguez-Morales et al.   Travel Medicine and Infectious Disease

On the Alert for Cytokine Storm: Immunopathology in COVID ‐19

(2020) Lauren A. Henderson et al.   Arthritis & Rheumatology

Tackling two pandemics: a plea on World Tuberculosis Day

(2020) Tom Wingfield et al.   Lancet Respiratory Medicine

Reduction and Functional Exhaustion of T Cells in Patients With Coronavirus Disease 2019 (COVID-19)

(2020) Bo Diao et al.   Frontiers in Immunology

Is Albumin Predictor of Mortality in COVID-19?

(2020) Francesco Violi et al.   ANTIOXIDANTS & REDOX SIGNALING

Coronavirus Disease 2019 Sepsis

(2020) Angel O. Coz Yataco et al.   CHEST

Cytokine Storms: Understanding COVID-19

(2020) Nilam Mangalmurti et al.   IMMUNITY

Can we use interleukin-6 (IL-6) blockade for coronavirus disease 2019 (COVID-19)-induced cytokine release syndrome (CRS)?

(2020) Bingwen Liu et al.   JOURNAL OF AUTOIMMUNITY

A single-cell atlas of the peripheral immune response in patients with severe COVID-19

(2020) Aaron J. Wilk et al.   NATURE MEDICINE

Common cardiovascular risk factors and in-hospital mortality in 3,894 patients with COVID-19: survival analysis and machine learning-based findings from the multicentre Italian CORIST Study

(2020) Augusto Di Castelnuovo et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Pathogenesis of COVID-19 from the Perspective of the Damage-Response Framework

(2020) Liise-anne Pirofski et al.   mBio

Immune Response, Inflammation, and the Clinical Spectrum of COVID-19

(2020) Luis F. García   Frontiers in Immunology

COVID-19 and comorbidities: Deleterious impact on infected patients

(2020) Hasan Ejaz et al.   Journal of Infection and Public Health

Phenotype and kinetics of SARS-CoV-2-specific T cells in COVID-19 patients with acute respiratory distress syndrome

(2020) Daniela Weiskopf et al.   Science Immunology

Immune Phenotyping Based on the Neutrophil-to-Lymphocyte Ratio and IgG Level Predicts Disease Severity and Outcome for Patients With COVID-19

(2020) Bicheng Zhang et al.   Frontiers in Molecular Biosciences

Immune-Inflammatory Parameters in COVID-19 Cases: A Systematic Review and Meta-Analysis

(2020) Xudong Feng et al.   Frontiers in Medicine

D-Dimer Concentrations and COVID-19 Severity: A Systematic Review and Meta-Analysis

(2020) Panagiotis Paliogiannis et al.   Frontiers in Public Health

D-dimer as a biomarker for disease severity and mortality in COVID-19 patients: a case control study

(2020) Yumeng Yao et al.   Journal of Intensive Care

Sepsis and Coronavirus Disease 2019

(2020) Jesús Beltrán-García et al.   CRITICAL CARE MEDICINE

The dynamic changes in cytokine responses in COVID-19: a snapshot of the current state of knowledge

(2020) Maja Buszko et al.   NATURE IMMUNOLOGY

An inflammatory cytokine signature predicts COVID-19 severity and survival

(2020) Diane Marie Del Valle et al.   NATURE MEDICINE

Efficacy of Tocilizumab in Patients Hospitalized with Covid-19

(2020) John H. Stone et al.   NEW ENGLAND JOURNAL OF MEDICINE

Immune dysfunction following COVID-19, especially in severe patients

(2020) Cong-Ying Song et al.   Scientific Reports

Duration of COVID-19: Data from an Italian Cohort and Potential Role for Steroids

(2020) Damiano D’Ardes et al.   Microorganisms

Clinical Characteristics and Outcomes Among COVID-19 Hospitalized Patients with Chronic Conditions: A Retrospective Single-Center Study

(2020) Ziyad Saeed Almalki et al.   Journal of Multidisciplinary Healthcare

COVID-19 and Sepsis Are Associated With Different Abnormalities in Plasma Procoagulant and Fibrinolytic Activity

(2020) Emma G. Bouck et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Pulmonary pathology of ARDS in COVID-19: A pathological review for clinicians

(2020) Sabrina Setembre Batah et al.   RESPIRATORY MEDICINE

Human Coronavirus: Host-Pathogen Interaction

(2019) To Sing Fung et al.   Annual Review of Microbiology

OUP accepted manuscript

(2018)   JOURNAL OF INFECTIOUS DISEASES

Cytokine release syndrome

(2018) Alexander Shimabukuro-Vornhagen et al.   Journal for ImmunoTherapy of Cancer

T-Cell Exhaustion in Chronic Infections: Reversing the State of Exhaustion and Reinvigorating Optimal Protective Immune Responses

(2018) Alireza Saeidi et al.   Frontiers in Immunology

Hyperferritinemia and inflammation

(2017) Kate F Kernan et al.   INTERNATIONAL IMMUNOLOGY

Cytokine storm and sepsis disease pathogenesis

(2017) Benjamin G. Chousterman et al.   Seminars in Immunopathology

Lymphocytosis and Lymphopenia Induced by Imported Infectious Diseases: A Controlled Cross-Sectional Study of 17,229 Diseased German Travelers Returning from the Tropics and Subtropics

(2016) Karl-Heinz Herbinger et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Human Monocytes Undergo Functional Re-programming during Sepsis Mediated by Hypoxia-Inducible Factor-1α

(2015) Irina N. Shalova et al.   IMMUNITY

Middle East Respiratory Syndrome Coronavirus Efficiently Infects Human Primary T Lymphocytes and Activates the Extrinsic and Intrinsic Apoptosis Pathways

(2015) Hin Chu et al.   JOURNAL OF INFECTIOUS DISEASES

The Pathogenesis of Sepsis

(2011) Deborah J. Stearns-Kurosawa et al.   Annual Review of Pathology-Mechanisms of Disease