Performance of a Four-Antigen Staphylococcus aureus Vaccine in Preclinical Models of Invasive S. aureus Disease

Safety, tolerability, and immunogenicity of a 4-antigen Staphylococcus aureus vaccine (SA4Ag): Results from a first-in-human randomised, placebo-controlled phase 1/2 study

(2017) Robert W. Frenck et al.   VACCINE

Preclinical Efficacy of Clumping Factor A in Prevention of Staphylococcus aureus Infection

(2016) Xue Li et al.   mBio

High Resolution Mapping of Bactericidal Monoclonal Antibody Binding Epitopes on Staphylococcus aureus Antigen MntC

(2016) Alexey V. Gribenko et al.   PLoS Pathogens

Meta-Analysis on Randomized Controlled Trials of Vaccines with QS-21 or ISCOMATRIX Adjuvant: Safety and Tolerability

(2016) Emilia Bigaeva et al.   PLoS One

Four-Component Staphylococcus aureus Vaccine 4C-Staph Enhances Fcγ Receptor Expression in Neutrophils and Monocytes and Mitigates S. aureus Infection in Neutropenic Mice

(2015) Antonina Torre et al.   INFECTION AND IMMUNITY

Vaccine composition formulated with a novel TLR7-dependent adjuvant induces high and broad protection againstStaphylococcus aureus

(2015) Fabio Bagnoli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Demonstration of the preclinical correlate of protection for Staphylococcus aureus clumping factor A in a murine model of infection

(2015) Ingrid L. Scully et al.   VACCINE

A randomized phase I study of the safety and immunogenicity of three ascending dose levels of a 3-antigen Staphylococcus aureus vaccine (SA3Ag) in healthy adults

(2015) Michael Nissen et al.   VACCINE

Safety and immunogenicity of an investigational 4-componentStaphylococcus aureusvaccine with or without AS03Badjuvant: Results of a randomized phase I trial

(2015) Jack Levy et al.   Human Vaccines & Immunotherapeutics

Efficacy profile of a bivalent Staphylococcus aureusglycoconjugated vaccine in adults on hemodialysis: Phase III randomized study

(2015) Ali Fattom et al.   Human Vaccines & Immunotherapeutics

Effect of an Investigational Vaccine for Preventing Staphylococcus aureus Infections After Cardiothoracic Surgery

(2013) Vance G. Fowler et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Three-Dimensional Structure and Biophysical Characterization of Staphylococcus aureus Cell Surface Antigen–Manganese Transporter MntC

(2013) Alexey Gribenko et al.   JOURNAL OF MOLECULAR BIOLOGY

Regulation of Staphylococcus aureus MntC Expression and Its Role in Response to Oxidative Stress

(2013) Luke D. Handke et al.   PLoS One

Vaccine review: “Staphyloccocus aureus vaccines: Problems and prospects”

(2013) Kathrin U. Jansen et al.   VACCINE

Capsular polysaccharides are an important immune evasion mechanism forStaphylococcus aureus

(2013) Jasdeep S. Nanra et al.   Human Vaccines & Immunotherapeutics

A Recombinant Clumping Factor A-Containing Vaccine Induces Functional Antibodies to Staphylococcus aureus That Are Not Observed after Natural Exposure

(2012) Julio Hawkins et al.   Clinical and Vaccine Immunology

Staphylococcus aureus Manganese Transport Protein C Is a Highly Conserved Cell Surface Protein That Elicits Protective Immunity Against S. aureus and Staphylococcus epidermidis

(2012) Annaliesa S. Anderson et al.   JOURNAL OF INFECTIOUS DISEASES

Immunization withStaphylococcus aureusiron regulated surface determinant B (IsdB) confers protection via Th17/IL17 pathway in a murine sepsis model

(2012) Amita Joshi et al.   Human Vaccines & Immunotherapeutics

A battle for iron: host sequestration and Staphylococcus aureus acquisition

(2011) Kathryn P. Haley et al.   MICROBES AND INFECTION

Global Changes in Staphylococcus aureus Gene Expression in Human Blood

(2011) Natalia Malachowa et al.   PLoS One

Preventing Surgical-Site Infections in Nasal Carriers ofStaphylococcus aureus

(2010) Lonneke G.M. Bode et al.   NEW ENGLAND JOURNAL OF MEDICINE